SG11201708624YA - Therapeutic antibodies and uses thereof - Google Patents
Therapeutic antibodies and uses thereofInfo
- Publication number
- SG11201708624YA SG11201708624YA SG11201708624YA SG11201708624YA SG11201708624YA SG 11201708624Y A SG11201708624Y A SG 11201708624YA SG 11201708624Y A SG11201708624Y A SG 11201708624YA SG 11201708624Y A SG11201708624Y A SG 11201708624YA SG 11201708624Y A SG11201708624Y A SG 11201708624YA
- Authority
- SG
- Singapore
- Prior art keywords
- therapeutic antibodies
- antibodies
- therapeutic
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
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- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
- A61K47/6817—Toxins
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- A61K47/6889—Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Toxicology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2015901423A AU2015901423A0 (en) | 2015-04-20 | Therapeutic antibodies and uses thereof | |
PCT/AU2016/000136 WO2016168885A1 (fr) | 2015-04-20 | 2016-04-20 | Anticorps thérapeutiques et utilisations de ceux-ci |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201708624YA true SG11201708624YA (en) | 2017-11-29 |
Family
ID=57142773
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201708624YA SG11201708624YA (en) | 2015-04-20 | 2016-04-20 | Therapeutic antibodies and uses thereof |
Country Status (10)
Country | Link |
---|---|
US (1) | US11198738B2 (fr) |
EP (1) | EP3285805B1 (fr) |
JP (1) | JP7063623B2 (fr) |
KR (1) | KR20170138530A (fr) |
CN (1) | CN107847593B (fr) |
AU (1) | AU2016250900B2 (fr) |
CA (1) | CA2983311A1 (fr) |
HK (1) | HK1247091A1 (fr) |
SG (1) | SG11201708624YA (fr) |
WO (1) | WO2016168885A1 (fr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2014409558B2 (en) * | 2014-10-23 | 2021-08-12 | Minomic International Ltd. | Monoclonal anti-GPC-1 antibodies and uses thereof |
WO2018199318A1 (fr) | 2017-04-28 | 2018-11-01 | 国立大学法人高知大学 | Anticorps anti-gpc-1 |
WO2019196111A1 (fr) * | 2018-04-13 | 2019-10-17 | 上海交通大学医学院附属瑞金医院 | Composé de type amide d'hétéroaryle utilisable contre les tumeurs multirésistantes aux médicaments anticancéreux, utilisation dans le traitement de cancers, et complexe moléculaire protéine-médicament |
CA3127450A1 (fr) * | 2019-01-22 | 2020-07-30 | Clemson University Research Foundation | Anticorps anti-elastine et methodes d'utilisation |
EP3883971A1 (fr) * | 2019-01-22 | 2021-09-29 | The United States of America, as represented by the Secretary, Department of Health and Human Services | Anticorps monoclonaux à haute affinité ciblant le glypicane-1 et procédés d'utilisation |
CN112175090B (zh) * | 2019-07-03 | 2024-04-26 | 深圳市雅臣智能生物工程有限公司 | 一种人溶菌酶结合物及其制备方法和应用 |
CN110893236A (zh) * | 2019-10-09 | 2020-03-20 | 中山大学 | 溶酶体靶向的抗体药物偶联物及其应用 |
CN111187350A (zh) * | 2019-12-30 | 2020-05-22 | 西安英创生物技术有限公司 | 一种与磷脂酰肌醇蛋白聚糖-1结合的抗原结合蛋白 |
WO2024083921A1 (fr) * | 2022-10-19 | 2024-04-25 | Centro Di Riferimento Oncologico Di Aviano | Anticorps monoclonal anti-gpc1, ses utilisations thérapeutiques et diagnostiques |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990014433A1 (fr) | 1989-05-24 | 1990-11-29 | The University Of Sydney | Anticorps monoclonaux reconnaissant les cellules malignes provenant de carcinomes cystiques |
US5622836A (en) * | 1989-05-24 | 1997-04-22 | The University Of Sydney | Monoclonal antibodies which recognize malignant cells from bladder carcinomas |
US7108986B2 (en) * | 1998-10-16 | 2006-09-19 | The Regents Of The University Of California | Glypican-1 in human breast cancer |
AUPR395801A0 (en) * | 2001-03-26 | 2001-04-26 | Austin Research Institute, The | Antibodies against cancer |
WO2005016285A2 (fr) | 2003-08-13 | 2005-02-24 | New York University | Compositions et methodes d'inhibition de la proteine slit et des interactions du glypican |
CN105074469A (zh) | 2013-04-01 | 2015-11-18 | 免疫医疗公司 | 用于胰腺癌早期检测和治疗的抗粘蛋白抗体 |
SG11201605784YA (en) * | 2014-01-17 | 2016-08-30 | Minomic Internat Ltd | Cell surface prostate cancer antigen for diagnosis |
AU2014409558B2 (en) | 2014-10-23 | 2021-08-12 | Minomic International Ltd. | Monoclonal anti-GPC-1 antibodies and uses thereof |
CN107531755B (zh) | 2015-01-16 | 2022-02-25 | 美侬米克国际有限公司 | 磷脂酰肌醇蛋白聚糖表位及其用途 |
-
2016
- 2016-04-20 CA CA2983311A patent/CA2983311A1/fr active Pending
- 2016-04-20 US US15/567,889 patent/US11198738B2/en active Active
- 2016-04-20 JP JP2017555213A patent/JP7063623B2/ja active Active
- 2016-04-20 EP EP16782389.7A patent/EP3285805B1/fr active Active
- 2016-04-20 KR KR1020177033428A patent/KR20170138530A/ko not_active Application Discontinuation
- 2016-04-20 CN CN201680036010.8A patent/CN107847593B/zh active Active
- 2016-04-20 WO PCT/AU2016/000136 patent/WO2016168885A1/fr active Application Filing
- 2016-04-20 SG SG11201708624YA patent/SG11201708624YA/en unknown
- 2016-04-20 AU AU2016250900A patent/AU2016250900B2/en active Active
-
2018
- 2018-05-21 HK HK18106580.3A patent/HK1247091A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
JP2018518455A (ja) | 2018-07-12 |
AU2016250900A1 (en) | 2017-11-02 |
WO2016168885A1 (fr) | 2016-10-27 |
JP7063623B2 (ja) | 2022-05-09 |
CA2983311A1 (fr) | 2016-10-27 |
EP3285805A4 (fr) | 2018-12-05 |
AU2016250900B2 (en) | 2022-03-17 |
HK1247091A1 (zh) | 2018-09-21 |
EP3285805A1 (fr) | 2018-02-28 |
US20190010247A1 (en) | 2019-01-10 |
KR20170138530A (ko) | 2017-12-15 |
CN107847593A (zh) | 2018-03-27 |
EP3285805B1 (fr) | 2021-05-26 |
CN107847593B (zh) | 2021-12-14 |
US11198738B2 (en) | 2021-12-14 |
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