SG11201708613SA - Novel crystal of uracil compound - Google Patents

Novel crystal of uracil compound

Info

Publication number
SG11201708613SA
SG11201708613SA SG11201708613SA SG11201708613SA SG11201708613SA SG 11201708613S A SG11201708613S A SG 11201708613SA SG 11201708613S A SG11201708613S A SG 11201708613SA SG 11201708613S A SG11201708613S A SG 11201708613SA SG 11201708613S A SG11201708613S A SG 11201708613SA
Authority
SG
Singapore
Prior art keywords
novel crystal
uracil compound
uracil
compound
crystal
Prior art date
Application number
SG11201708613SA
Other languages
English (en)
Inventor
Masayoshi Fukuoka
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Publication of SG11201708613SA publication Critical patent/SG11201708613SA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/20Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D239/22Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs
SG11201708613SA 2015-05-01 2016-04-28 Novel crystal of uracil compound SG11201708613SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2015093862 2015-05-01
PCT/JP2016/063495 WO2016178416A1 (ja) 2015-05-01 2016-04-28 ウラシル化合物の新規結晶

Publications (1)

Publication Number Publication Date
SG11201708613SA true SG11201708613SA (en) 2017-11-29

Family

ID=57217651

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201708613SA SG11201708613SA (en) 2015-05-01 2016-04-28 Novel crystal of uracil compound

Country Status (15)

Country Link
US (1) US10259792B2 (ko)
EP (1) EP3290406A4 (ko)
JP (1) JP6479970B2 (ko)
KR (2) KR20200039846A (ko)
CN (1) CN107531646B (ko)
AU (1) AU2016258388B2 (ko)
BR (1) BR112017023649A2 (ko)
CA (1) CA2984724C (ko)
HK (1) HK1245770A1 (ko)
MX (1) MX2017013969A (ko)
MY (1) MY185785A (ko)
PH (1) PH12017501948A1 (ko)
RU (1) RU2686722C1 (ko)
SG (1) SG11201708613SA (ko)
WO (1) WO2016178416A1 (ko)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014107622A1 (en) 2013-01-07 2014-07-10 University Of Southern California Deoxyuridine triphosphatase inhibitors
JP6513095B2 (ja) 2014-01-03 2019-05-15 ユニバーシティ オブ サザン カリフォルニア ヘテロ原子含有デオキシウリジントリホスファターゼ阻害剤
US10544105B2 (en) 2015-07-08 2020-01-28 Cv6 Therapeutics (Ni) Limited Deoxyuridine triphosphatase inhibitors containing cyclopropano linkage
EP3319939A1 (en) 2015-07-08 2018-05-16 CV6 Therapeutics (NI) Limited Hydantoin containing deoxyuridine triphosphatase inhibitors
US10570100B2 (en) 2015-07-08 2020-02-25 University Of Southern California Deoxyuridine triphosphatase inhibitors containing amino sulfonyl linkage
WO2017006270A1 (en) 2015-07-08 2017-01-12 University Of Southern California Deoxyuridine triphosphatase inhibitors
WO2018098207A1 (en) 2016-11-23 2018-05-31 Cv6 Therapeutics (Ni) Limited Hydantoin containing deoxyuridine triphosphatase inhibitors
WO2018098204A1 (en) 2016-11-23 2018-05-31 Cv6 Therapeutics (Ni) Limited 6-membered uracil isosteres
WO2018098208A1 (en) 2016-11-23 2018-05-31 Cv6 Therapeutics (Ni) Limited Nitrogen ring linked deoxyuridine triphosphatase inhibitors
US10858344B2 (en) 2016-11-23 2020-12-08 Cv6 Therapeutics (Ni) Limited Hydantoin containing deoxyuridine triphosphatase inhibitors
WO2018098209A1 (en) 2016-11-23 2018-05-31 Cv6 Therapeutics (Ni) Limited Amino sulfonyl compounds
US11247984B2 (en) 2017-01-05 2022-02-15 Cv6 Therapeutics (Ni) Limited Uracil containing compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2010013275A (es) * 2008-06-03 2011-03-15 Taiho Pharmaceutical Co Ltd Compuesto novedoso de uracilo o su sal que tiene actividad inhibidora de desoxiuridin trifosfatasa de humano.
TWI466870B (zh) * 2009-11-30 2015-01-01 Taiho Pharmaceutical Co Ltd Anti - tumor efficacy enhancer
JP2013032293A (ja) * 2009-11-30 2013-02-14 Taiho Yakuhin Kogyo Kk ヒトdUTPase阻害活性を有する5−フルオロウラシル化合物又はその塩

Also Published As

Publication number Publication date
JPWO2016178416A1 (ja) 2017-10-26
PH12017501948A1 (en) 2018-03-19
JP6479970B2 (ja) 2019-03-06
KR20170137916A (ko) 2017-12-13
EP3290406A4 (en) 2018-11-14
MY185785A (en) 2021-06-08
CN107531646A (zh) 2018-01-02
RU2686722C1 (ru) 2019-04-30
WO2016178416A1 (ja) 2016-11-10
KR20200039846A (ko) 2020-04-16
CN107531646B (zh) 2020-11-03
AU2016258388B2 (en) 2019-03-28
US10259792B2 (en) 2019-04-16
CA2984724C (en) 2020-06-02
AU2016258388A1 (en) 2017-11-23
MX2017013969A (es) 2018-02-21
EP3290406A1 (en) 2018-03-07
US20180134666A1 (en) 2018-05-17
HK1245770A1 (zh) 2018-08-31
BR112017023649A2 (pt) 2018-07-17
CA2984724A1 (en) 2016-11-10

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