SG11201708506QA - Methods for treating cancer with a stat3 pathway inhibitor and kinase inhibitor - Google Patents

Methods for treating cancer with a stat3 pathway inhibitor and kinase inhibitor

Info

Publication number
SG11201708506QA
SG11201708506QA SG11201708506QA SG11201708506QA SG11201708506QA SG 11201708506Q A SG11201708506Q A SG 11201708506QA SG 11201708506Q A SG11201708506Q A SG 11201708506QA SG 11201708506Q A SG11201708506Q A SG 11201708506QA SG 11201708506Q A SG11201708506Q A SG 11201708506QA
Authority
SG
Singapore
Prior art keywords
inhibitor
methods
treating cancer
stat3 pathway
kinase inhibitor
Prior art date
Application number
SG11201708506QA
Other languages
English (en)
Inventor
Chiang J Li
Youzhi Li
Harry Rogoff
Yuan Gao
Janet Huang
Original Assignee
Boston Biomedical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston Biomedical Inc filed Critical Boston Biomedical Inc
Publication of SG11201708506QA publication Critical patent/SG11201708506QA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11201708506QA 2015-04-27 2016-04-26 Methods for treating cancer with a stat3 pathway inhibitor and kinase inhibitor SG11201708506QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562153385P 2015-04-27 2015-04-27
PCT/US2016/029328 WO2016176190A1 (en) 2015-04-27 2016-04-26 Methods for treating cancer with a stat3 pathway inhibitor and kinase inhibitor

Publications (1)

Publication Number Publication Date
SG11201708506QA true SG11201708506QA (en) 2017-11-29

Family

ID=56081544

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201708506QA SG11201708506QA (en) 2015-04-27 2016-04-26 Methods for treating cancer with a stat3 pathway inhibitor and kinase inhibitor

Country Status (16)

Country Link
US (1) US20180250261A1 (ja)
EP (1) EP3288552A1 (ja)
JP (2) JP2018514557A (ja)
KR (1) KR20170141716A (ja)
CN (1) CN107683137A (ja)
AU (1) AU2016255034A1 (ja)
BR (1) BR112017022958A2 (ja)
CA (1) CA2983468A1 (ja)
EA (1) EA201792320A1 (ja)
HK (1) HK1252172A1 (ja)
IL (1) IL255023A0 (ja)
MX (1) MX2017013816A (ja)
PH (1) PH12017501882A1 (ja)
SG (1) SG11201708506QA (ja)
TW (1) TW201713329A (ja)
WO (1) WO2016176190A1 (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101854802B (zh) 2007-09-10 2014-12-03 北京强新生物科技有限公司 用于癌症治疗的组合物和方法
CA2908380A1 (en) 2013-04-09 2014-10-16 Boston Biomedical, Inc. Methods for treating cancer
WO2018005444A2 (en) * 2016-06-28 2018-01-04 Boston Biomedical, Inc. Methods for treating cancer
CA3045306A1 (en) 2016-11-29 2018-06-07 Boston Biomedical, Inc. Naphthofuran derivatives, preparation, and methods of use thereof
US10646464B2 (en) 2017-05-17 2020-05-12 Boston Biomedical, Inc. Methods for treating cancer
WO2022178957A1 (zh) * 2021-02-25 2022-09-01 毕庶壮 Napabucasin的制药用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2591028T3 (es) * 2007-09-06 2016-11-24 Boston Biomedical, Inc. Composiciones de inhibidores de quinasa y su uso para el tratamiento del cáncer y otras enfermedades relacionadas con quinasas
CN101854802B (zh) 2007-09-10 2014-12-03 北京强新生物科技有限公司 用于癌症治疗的组合物和方法
CA2908380A1 (en) * 2013-04-09 2014-10-16 Boston Biomedical, Inc. Methods for treating cancer

Also Published As

Publication number Publication date
JP2021121629A (ja) 2021-08-26
MX2017013816A (es) 2018-11-12
CA2983468A1 (en) 2016-11-03
HK1252172A1 (zh) 2019-05-17
EP3288552A1 (en) 2018-03-07
PH12017501882A1 (en) 2018-03-05
KR20170141716A (ko) 2017-12-26
JP2018514557A (ja) 2018-06-07
US20180250261A1 (en) 2018-09-06
AU2016255034A1 (en) 2017-11-02
WO2016176190A1 (en) 2016-11-03
EA201792320A1 (ru) 2018-02-28
IL255023A0 (en) 2017-12-31
BR112017022958A2 (pt) 2018-07-17
CN107683137A (zh) 2018-02-09
TW201713329A (zh) 2017-04-16

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