HK1252172A1 - 用於使用stat3途徑抑制劑和激酶抑制劑治療癌症的方法 - Google Patents
用於使用stat3途徑抑制劑和激酶抑制劑治療癌症的方法Info
- Publication number
- HK1252172A1 HK1252172A1 HK18111573.2A HK18111573A HK1252172A1 HK 1252172 A1 HK1252172 A1 HK 1252172A1 HK 18111573 A HK18111573 A HK 18111573A HK 1252172 A1 HK1252172 A1 HK 1252172A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- inhibitor
- methods
- treating cancer
- stat3 pathway
- kinase inhibitor
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 101100311214 Xenopus laevis stat3.1 gene Proteins 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 229940043355 kinase inhibitor Drugs 0.000 title 1
- 230000037361 pathway Effects 0.000 title 1
- 239000003757 phosphotransferase inhibitor Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562153385P | 2015-04-27 | 2015-04-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1252172A1 true HK1252172A1 (zh) | 2019-05-17 |
Family
ID=56081544
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18111573.2A HK1252172A1 (zh) | 2015-04-27 | 2018-09-07 | 用於使用stat3途徑抑制劑和激酶抑制劑治療癌症的方法 |
Country Status (16)
Country | Link |
---|---|
US (1) | US20180250261A1 (zh) |
EP (1) | EP3288552A1 (zh) |
JP (2) | JP2018514557A (zh) |
KR (1) | KR20170141716A (zh) |
CN (1) | CN107683137A (zh) |
AU (1) | AU2016255034A1 (zh) |
BR (1) | BR112017022958A2 (zh) |
CA (1) | CA2983468A1 (zh) |
EA (1) | EA201792320A1 (zh) |
HK (1) | HK1252172A1 (zh) |
IL (1) | IL255023A0 (zh) |
MX (1) | MX2017013816A (zh) |
PH (1) | PH12017501882A1 (zh) |
SG (1) | SG11201708506QA (zh) |
TW (1) | TW201713329A (zh) |
WO (1) | WO2016176190A1 (zh) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104586832B (zh) | 2007-09-10 | 2018-02-16 | 北京强新生物科技有限公司 | 用于癌症治疗的组合物和方法 |
RU2015147696A (ru) | 2013-04-09 | 2017-05-12 | Бостон Байомедикал, Инк. | Способы лечения злокачественной опухоли |
JP2019519573A (ja) * | 2016-06-28 | 2019-07-11 | ボストン バイオメディカル, インコーポレイテッド | がんを処置するための方法 |
WO2018102427A1 (en) | 2016-11-29 | 2018-06-07 | Boston Biomedical, Inc. | Naphthofuran derivatives, preparation, and methods of use thereof |
CA3062656A1 (en) | 2017-05-17 | 2018-11-22 | Boston Biomedical, Inc. | Methods for treating cancer |
WO2022178957A1 (zh) * | 2021-02-25 | 2022-09-01 | 毕庶壮 | Napabucasin的制药用途 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5452490B2 (ja) * | 2007-09-06 | 2014-03-26 | ボストン バイオメディカル, インコーポレイテッド | キナーゼ阻害剤の組成物ならびに癌およびキナーゼに関連する他の疾患の治療のためのそれらの使用 |
CN104586832B (zh) * | 2007-09-10 | 2018-02-16 | 北京强新生物科技有限公司 | 用于癌症治疗的组合物和方法 |
RU2015147696A (ru) * | 2013-04-09 | 2017-05-12 | Бостон Байомедикал, Инк. | Способы лечения злокачественной опухоли |
-
2016
- 2016-04-26 WO PCT/US2016/029328 patent/WO2016176190A1/en active Application Filing
- 2016-04-26 AU AU2016255034A patent/AU2016255034A1/en not_active Abandoned
- 2016-04-26 MX MX2017013816A patent/MX2017013816A/es unknown
- 2016-04-26 US US15/569,236 patent/US20180250261A1/en not_active Abandoned
- 2016-04-26 KR KR1020177032743A patent/KR20170141716A/ko unknown
- 2016-04-26 EP EP16725260.0A patent/EP3288552A1/en not_active Withdrawn
- 2016-04-26 CA CA2983468A patent/CA2983468A1/en not_active Abandoned
- 2016-04-26 JP JP2017556740A patent/JP2018514557A/ja not_active Withdrawn
- 2016-04-26 EA EA201792320A patent/EA201792320A1/ru unknown
- 2016-04-26 BR BR112017022958A patent/BR112017022958A2/pt not_active Application Discontinuation
- 2016-04-26 SG SG11201708506QA patent/SG11201708506QA/en unknown
- 2016-04-26 CN CN201680032224.8A patent/CN107683137A/zh active Pending
- 2016-04-27 TW TW105113235A patent/TW201713329A/zh unknown
-
2017
- 2017-10-15 IL IL255023A patent/IL255023A0/en unknown
- 2017-10-18 PH PH12017501882A patent/PH12017501882A1/en unknown
-
2018
- 2018-09-07 HK HK18111573.2A patent/HK1252172A1/zh unknown
-
2021
- 2021-05-25 JP JP2021087483A patent/JP2021121629A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
SG11201708506QA (en) | 2017-11-29 |
KR20170141716A (ko) | 2017-12-26 |
JP2021121629A (ja) | 2021-08-26 |
US20180250261A1 (en) | 2018-09-06 |
CN107683137A (zh) | 2018-02-09 |
CA2983468A1 (en) | 2016-11-03 |
MX2017013816A (es) | 2018-11-12 |
BR112017022958A2 (pt) | 2018-07-17 |
PH12017501882A1 (en) | 2018-03-05 |
TW201713329A (zh) | 2017-04-16 |
EP3288552A1 (en) | 2018-03-07 |
AU2016255034A1 (en) | 2017-11-02 |
IL255023A0 (en) | 2017-12-31 |
JP2018514557A (ja) | 2018-06-07 |
EA201792320A1 (ru) | 2018-02-28 |
WO2016176190A1 (en) | 2016-11-03 |
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