SG11201707325RA - Method of determining the risk of developing breast cancer by detecting the expression levels of micrornas (mirnas) - Google Patents
Method of determining the risk of developing breast cancer by detecting the expression levels of micrornas (mirnas)Info
- Publication number
- SG11201707325RA SG11201707325RA SG11201707325RA SG11201707325RA SG11201707325RA SG 11201707325R A SG11201707325R A SG 11201707325RA SG 11201707325R A SG11201707325R A SG 11201707325RA SG 11201707325R A SG11201707325R A SG 11201707325RA SG 11201707325R A SG11201707325R A SG 11201707325RA
- Authority
- SG
- Singapore
- Prior art keywords
- micrornas
- mirnas
- risk
- detecting
- determining
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/20—Polymerase chain reaction [PCR]; Primer or probe design; Probe optimisation
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SG10201501781W | 2015-03-09 | ||
| PCT/SG2016/050113 WO2016144265A1 (en) | 2015-03-09 | 2016-03-09 | Method of determining the risk of developing breast cancer by detecting the expression levels of micrornas (mirnas) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201707325RA true SG11201707325RA (en) | 2017-10-30 |
Family
ID=56880404
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201707325RA SG11201707325RA (en) | 2015-03-09 | 2016-03-09 | Method of determining the risk of developing breast cancer by detecting the expression levels of micrornas (mirnas) |
| SG10201908277T SG10201908277TA (en) | 2015-03-09 | 2016-03-09 | Method of determining the risk of developing breast cancer by detecting the expression levels of micrornas (mirnas) |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201908277T SG10201908277TA (en) | 2015-03-09 | 2016-03-09 | Method of determining the risk of developing breast cancer by detecting the expression levels of micrornas (mirnas) |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20180230544A1 (en) |
| EP (2) | EP3916106A1 (en) |
| CN (3) | CN116064801A (en) |
| ES (1) | ES2882104T3 (en) |
| HK (1) | HK1249555A1 (en) |
| SG (2) | SG11201707325RA (en) |
| WO (1) | WO2016144265A1 (en) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106729751B (en) * | 2015-11-20 | 2020-03-06 | 中国医学科学院肿瘤医院 | Application of microRNA molecule in detection and treatment of breast cancer |
| JPWO2018056432A1 (en) * | 2016-09-26 | 2019-07-04 | 東レ株式会社 | Method for detecting hemolysis of blood sample and chip for hemolysis detection |
| US20200123619A1 (en) * | 2017-04-06 | 2020-04-23 | The University Of Vermont And State Agricultural College | Mirna signature expression in cancer |
| EP3701050B1 (en) | 2017-10-24 | 2024-03-06 | Université Paris Cité | Diagnosis and/or prognosis of her2-dependent cancer using one or more mirna as a biomarker |
| CN107815492A (en) * | 2017-12-08 | 2018-03-20 | 武汉科技大学 | A kind of detection method based on QPCR Diagnosis of Breast cancers |
| JP7298913B2 (en) * | 2017-12-13 | 2023-06-27 | 国立大学法人広島大学 | Methods to Aid in Breast Cancer Detection |
| GB201802404D0 (en) * | 2018-02-14 | 2018-03-28 | Univ Malta | Methods |
| CN108531586B (en) * | 2018-03-19 | 2022-03-29 | 朱伟 | Circulating miRNA marker on X chromosome related to breast cancer auxiliary diagnosis and application thereof |
| CN109337978B (en) * | 2018-07-03 | 2023-12-01 | 华中科技大学同济医学院附属同济医院 | Application of miRNA in preparation of advanced serous epithelial ovarian cancer chemotherapy drug resistance evaluation kit |
| CN108950003B (en) * | 2018-09-10 | 2022-02-11 | 山东大学齐鲁医院 | miRNA marker for diagnosing breast cancer and application of miRNA thereof |
| CN109182524A (en) * | 2018-09-29 | 2019-01-11 | 江苏医诺万细胞诊疗有限公司 | MiRNA combination marker and its application of a kind of auxiliary diagnosis cervical carcinoma and its precancerous lesion |
| CN109609630B (en) * | 2018-12-03 | 2023-01-13 | 哈尔滨医科大学 | Molecular marker for early gastric cancer diagnosis and application thereof |
| CN109295233A (en) * | 2018-12-10 | 2019-02-01 | 复旦大学附属中山医院 | A kind of kit of joint-detection miRNA diagnosis colorectal cancer |
| CN109593851B (en) * | 2018-12-24 | 2022-02-11 | 朱伟 | Plasma miRNA marker related to breast cancer auxiliary diagnosis and application thereof |
| CN109609633B (en) * | 2018-12-24 | 2022-02-11 | 朱伟 | Serum miRNA marker related to breast cancer auxiliary diagnosis and application thereof |
| CN117683885A (en) * | 2019-04-30 | 2024-03-12 | 觅瑞实验室私人有限公司 | miRNA marker combination and kit for detecting gastric cancer |
| EP3772543B1 (en) * | 2019-08-09 | 2023-09-27 | Albert-Ludwigs-Universität Freiburg | Method for diagnosing breast cancer |
| CN112516155A (en) * | 2019-09-18 | 2021-03-19 | 四川大学华西医院 | Gene therapy preparation for three-negative breast cancer |
| CN110804659B (en) * | 2019-10-23 | 2023-02-03 | 华南农业大学 | Application of serum exosome ssc-miR-92b-3p as molecular marker for early pregnancy diagnosis of sows |
| CN110787181B (en) * | 2019-12-10 | 2022-11-15 | 合肥市第二人民医院 | Group of miRNA and application thereof in biological targeted therapy of breast cancer |
| CN112980947A (en) * | 2019-12-12 | 2021-06-18 | 中国科学院大连化学物理研究所 | Primer and kit for detecting circulating microRNA (microribonucleic acid) related to lung cancer diagnosis and treatment |
| CN111653315A (en) * | 2020-05-29 | 2020-09-11 | 杭州广科安德生物科技有限公司 | Method for constructing mathematical model for detecting breast cancer in vitro and application thereof |
| CN111518914B (en) * | 2020-06-09 | 2021-12-24 | 上海圣梓茂生物科技有限公司 | MiRNA marker combination, kit and method for detecting breast cancer |
| WO2022051141A1 (en) * | 2020-09-03 | 2022-03-10 | The Trustees Of Indiana University | Methods for early detection of breast cancer |
| CN113151477B (en) * | 2021-05-08 | 2022-04-15 | 武汉大学中南医院 | miRNA marker for detecting intestinal cancer and application thereof |
| CN113215256A (en) * | 2021-05-10 | 2021-08-06 | 深圳市展行生物有限公司 | Method for evaluating breast cancer risk and miRNA combination used in same |
| WO2023014297A2 (en) * | 2021-08-02 | 2023-02-09 | National University Of Singapore | Circulating microrna panel for the early detection of breast cancer and methods thereof |
| WO2023170659A1 (en) | 2022-03-11 | 2023-09-14 | Consejo Nacional De Investigaciones Cientificas Y Tecnicas (Conicet) | Breast cancer diagnostic and treatment |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101988061A (en) * | 2009-07-30 | 2011-03-23 | 江苏命码生物科技有限公司 | Breast cancer detecting marker as well as detecting method, kit and biological chip thereof |
| US20130065778A1 (en) * | 2010-01-26 | 2013-03-14 | Yale University | MicroRNA Signatures Predicting Responsiveness To Anti-HER2 Therapy |
| CN101921760B (en) * | 2010-09-08 | 2012-02-01 | 南京医科大学 | Serum/plasma miRNA marker associated with breast cancer and application thereof |
| GB2533873B (en) * | 2011-10-19 | 2016-08-31 | Council Scient Ind Res | Biomarkers useful for detection of types, grades and stages of human breast cancer |
| US10316367B2 (en) * | 2012-06-21 | 2019-06-11 | Ruprecht-Karls-Universität Heidelberg | Circulating miRNAs as markers for breast cancer |
| WO2014129975A1 (en) * | 2013-02-20 | 2014-08-28 | Singapore Health Services Pte Ltd | Identification of circulating microrna signatures for breast cancer detection |
| EP2961386B1 (en) * | 2013-02-28 | 2019-07-10 | The General Hospital Corporation | Mirna profiling compositions and methods of use |
| WO2014193309A1 (en) * | 2013-05-30 | 2014-12-04 | Agency For Science, Technology And Research | Method For Determining Cancer Prognosis |
-
2016
- 2016-03-09 CN CN202211111823.2A patent/CN116064801A/en active Pending
- 2016-03-09 US US15/557,457 patent/US20180230544A1/en active Pending
- 2016-03-09 CN CN201680014611.9A patent/CN107429295B/en active Active
- 2016-03-09 EP EP21161797.2A patent/EP3916106A1/en active Pending
- 2016-03-09 ES ES16762077T patent/ES2882104T3/en active Active
- 2016-03-09 SG SG11201707325RA patent/SG11201707325RA/en unknown
- 2016-03-09 WO PCT/SG2016/050113 patent/WO2016144265A1/en active Application Filing
- 2016-03-09 CN CN202211111821.3A patent/CN116064800A/en active Pending
- 2016-03-09 SG SG10201908277T patent/SG10201908277TA/en unknown
- 2016-03-09 EP EP16762077.2A patent/EP3268494B1/en active Active
-
2018
- 2018-07-11 HK HK18108972.5A patent/HK1249555A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN107429295A (en) | 2017-12-01 |
| HK1249555A1 (en) | 2018-11-02 |
| EP3916106A1 (en) | 2021-12-01 |
| EP3268494A1 (en) | 2018-01-17 |
| SG10201908277TA (en) | 2019-10-30 |
| US20180230544A1 (en) | 2018-08-16 |
| CN116064800A (en) | 2023-05-05 |
| EP3268494A4 (en) | 2018-11-07 |
| CN116064801A (en) | 2023-05-05 |
| ES2882104T3 (en) | 2021-12-01 |
| CN107429295B (en) | 2022-09-30 |
| WO2016144265A1 (en) | 2016-09-15 |
| EP3268494B1 (en) | 2021-04-21 |
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