SG11201706562QA - NON-MEMBRANE DISRUPTIVE p53 ACTIVATING STAPLED PEPTIDES - Google Patents

NON-MEMBRANE DISRUPTIVE p53 ACTIVATING STAPLED PEPTIDES

Info

Publication number
SG11201706562QA
SG11201706562QA SG11201706562QA SG11201706562QA SG11201706562QA SG 11201706562Q A SG11201706562Q A SG 11201706562QA SG 11201706562Q A SG11201706562Q A SG 11201706562QA SG 11201706562Q A SG11201706562Q A SG 11201706562QA SG 11201706562Q A SG11201706562Q A SG 11201706562QA
Authority
SG
Singapore
Prior art keywords
activating
stapled peptides
membrane disruptive
disruptive
membrane
Prior art date
Application number
SG11201706562QA
Other languages
English (en)
Inventor
Yaw Sing Tan
Christopher John Brown
Chandra S Verma
Gago Fernando Jose Ferrer
David P Lane
Thomas Joseph
Original Assignee
Agency Science Tech & Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency Science Tech & Res filed Critical Agency Science Tech & Res
Publication of SG11201706562QA publication Critical patent/SG11201706562QA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG11201706562QA 2015-02-13 2016-02-15 NON-MEMBRANE DISRUPTIVE p53 ACTIVATING STAPLED PEPTIDES SG11201706562QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SG10201501119W 2015-02-13
PCT/SG2016/050079 WO2016130092A1 (en) 2015-02-13 2016-02-15 Non-membrane disruptive p53 activating stapled peptides

Publications (1)

Publication Number Publication Date
SG11201706562QA true SG11201706562QA (en) 2017-09-28

Family

ID=56614951

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201706562QA SG11201706562QA (en) 2015-02-13 2016-02-15 NON-MEMBRANE DISRUPTIVE p53 ACTIVATING STAPLED PEPTIDES

Country Status (6)

Country Link
US (1) US11319344B2 (https=)
EP (1) EP3256484B1 (https=)
JP (1) JP7028643B2 (https=)
CN (1) CN107531759B (https=)
SG (1) SG11201706562QA (https=)
WO (1) WO2016130092A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020027585A2 (ko) * 2018-07-31 2020-02-06 주식회사 레모넥스 폴리펩타이드 전달용 조성물
CN121064336A (zh) * 2018-07-31 2025-12-05 雷莫内克斯生物制药有限公司 多肽递送组合物
CN115052614B (zh) * 2019-12-05 2025-10-21 亚洲大学校产学协力团 包含肽或其混合物作为活性成分的用于预防或治疗白塞氏病和类风湿性关节炎的药物组合物
CN111613275B (zh) * 2020-05-26 2021-03-16 中国海洋大学 一种基于rmsd多特征的药物分子动力学结果分析方法
IT202000016807A1 (it) * 2020-07-10 2022-01-10 Humanitas Mirasole Spa Peptidi associati a tumore e loro impiego
CN116801908A (zh) 2020-10-14 2023-09-22 丹娜法伯癌症研究院 用于降解病毒和宿主蛋白的嵌合缀合物和使用方法
WO2024051616A1 (zh) * 2022-09-09 2024-03-14 湖南大学 一种多肽及其制备方法和用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009149339A2 (en) 2008-06-05 2009-12-10 University Of Maryland, Baltimore P53 activator peptides
JP5764127B2 (ja) * 2009-08-17 2015-08-12 ロシュ グリクアート アーゲー 標的化イムノコンジュゲート
US20120328692A1 (en) 2011-06-24 2012-12-27 University Of Maryland, Baltimore Potent d-peptide antagonists of mdm2 and mdmx for anticancer therapy
EP2904000A4 (en) * 2012-10-01 2016-04-20 Agency Science Tech & Res PEPTIDES AND METHOD FOR THE TREATMENT OF CANCER
EP3391898A3 (en) * 2013-03-13 2019-02-13 President and Fellows of Harvard College Stapled and stitched polypeptides and uses thereof
US20150010932A1 (en) * 2013-07-02 2015-01-08 Salk Institute For Biological Studies Methods for assaying protein-protein interactions

Also Published As

Publication number Publication date
US20180030090A1 (en) 2018-02-01
US11319344B2 (en) 2022-05-03
EP3256484A1 (en) 2017-12-20
CN107531759A (zh) 2018-01-02
JP7028643B2 (ja) 2022-03-02
JP2018507689A (ja) 2018-03-22
WO2016130092A1 (en) 2016-08-18
EP3256484B1 (en) 2021-06-23
EP3256484A4 (en) 2018-07-25
CN107531759B (zh) 2021-11-16

Similar Documents

Publication Publication Date Title
IL275298A (en) Mitochondria-targeted peptides
PL3289985T3 (pl) Stapler chirurgiczny
EP3270945A4 (en) Selective mcl-1 binding peptides
SG11201706562QA (en) NON-MEMBRANE DISRUPTIVE p53 ACTIVATING STAPLED PEPTIDES
EP3448879B8 (en) Claudin-6 peptides
IL263292A (en) Protease-resistant mono-lipidated peptides
GB201520539D0 (en) Peptides
GB201604468D0 (en) Peptides
GB201520546D0 (en) Peptides
GB201520543D0 (en) Peptides
GB201520536D0 (en) Peptides
GB201520544D0 (en) Peptides
GB201520545D0 (en) Peptides
GB201520550D0 (en) Peptides
GB201520541D0 (en) Peptides
GB201607535D0 (en) Peptides
GB201520542D0 (en) Peptides
GB201520548D0 (en) Peptides
GB201620963D0 (en) Antimicrobial peptides
EP3330045A4 (en) Stapling device
GB201518700D0 (en) Peptides
IL266419A (en) Binding peptides
HK40013497A (en) Binding peptides
HK40015113A (en) Modified peptides
GB201715378D0 (en) Peptides