IL263292A - Protease-resistant mono-lipidated peptides - Google Patents

Protease-resistant mono-lipidated peptides

Info

Publication number
IL263292A
IL263292A IL263292A IL26329218A IL263292A IL 263292 A IL263292 A IL 263292A IL 263292 A IL263292 A IL 263292A IL 26329218 A IL26329218 A IL 26329218A IL 263292 A IL263292 A IL 263292A
Authority
IL
Israel
Prior art keywords
protease
lipidated peptides
mono
resistant mono
resistant
Prior art date
Application number
IL263292A
Other languages
Hebrew (he)
Original Assignee
Medimmune Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medimmune Ltd filed Critical Medimmune Ltd
Publication of IL263292A publication Critical patent/IL263292A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Obesity (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
IL263292A 2016-06-09 2018-11-26 Protease-resistant mono-lipidated peptides IL263292A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662347693P 2016-06-09 2016-06-09
PCT/EP2017/063905 WO2017211922A2 (en) 2016-06-09 2017-06-08 Protease-resistant mono-lipidated peptides

Publications (1)

Publication Number Publication Date
IL263292A true IL263292A (en) 2018-12-31

Family

ID=59078034

Family Applications (1)

Application Number Title Priority Date Filing Date
IL263292A IL263292A (en) 2016-06-09 2018-11-26 Protease-resistant mono-lipidated peptides

Country Status (10)

Country Link
EP (1) EP3468987A2 (en)
JP (1) JP2019525732A (en)
KR (1) KR20190017017A (en)
CN (1) CN109195984A (en)
AU (1) AU2017277594A1 (en)
BR (1) BR112018072968A2 (en)
CA (1) CA3025592A1 (en)
IL (1) IL263292A (en)
MX (1) MX2018014966A (en)
WO (1) WO2017211922A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA202090649A1 (en) 2017-09-22 2020-06-29 Регенерон Фармасьютикалз, Инк. Glucagon-like Peptide 1 RECEPTOR AGONISTS AND THEIR APPLICATION
HRP20221054T1 (en) 2018-04-05 2022-11-11 Sun Pharmaceutical Industries Limited Novel glp-1 analogues
MX2023008330A (en) 2021-01-20 2024-01-18 Viking Therapeutics Inc Compositions and methods for the treatment of metabolic and liver disorders.
TW202346323A (en) * 2022-02-07 2023-12-01 英商梅迪繆思有限公司 Glp-1 and glucagon dual agonist peptides with improved biological stability

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2057189B1 (en) * 2006-08-25 2013-03-06 Novo Nordisk A/S Acylated exendin-4 compounds
EP3415526A1 (en) * 2013-12-13 2018-12-19 MedImmune Limited Protease resistant peptides
TWI726889B (en) * 2015-06-10 2021-05-11 英商梅迪繆思有限公司 Protease-resistant lipidated peptides

Also Published As

Publication number Publication date
BR112018072968A2 (en) 2019-02-19
CA3025592A1 (en) 2017-12-14
CN109195984A (en) 2019-01-11
WO2017211922A2 (en) 2017-12-14
MX2018014966A (en) 2019-08-14
JP2019525732A (en) 2019-09-12
KR20190017017A (en) 2019-02-19
AU2017277594A1 (en) 2019-02-07
EP3468987A2 (en) 2019-04-17
WO2017211922A3 (en) 2018-01-18

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