SG11201609879SA - Novel promoters for high level expression - Google Patents

Novel promoters for high level expression

Info

Publication number
SG11201609879SA
SG11201609879SA SG11201609879SA SG11201609879SA SG11201609879SA SG 11201609879S A SG11201609879S A SG 11201609879SA SG 11201609879S A SG11201609879S A SG 11201609879SA SG 11201609879S A SG11201609879S A SG 11201609879SA SG 11201609879S A SG11201609879S A SG 11201609879SA
Authority
SG
Singapore
Prior art keywords
high level
level expression
novel promoters
promoters
novel
Prior art date
Application number
SG11201609879SA
Other languages
English (en)
Inventor
Yuansheng Yang
Cheng Leong Steven Ho
Fang Shiyi Goh
Original Assignee
Agency Science Tech & Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency Science Tech & Res filed Critical Agency Science Tech & Res
Priority to SG11201609879SA priority Critical patent/SG11201609879SA/en
Publication of SG11201609879SA publication Critical patent/SG11201609879SA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/15—Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/60—Vector systems having a special element relevant for transcription from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/90—Vector systems having a special element relevant for transcription from vertebrates avian

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SG11201609879SA 2014-06-18 2015-06-17 Novel promoters for high level expression SG11201609879SA (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SG11201609879SA SG11201609879SA (en) 2014-06-18 2015-06-17 Novel promoters for high level expression

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SG10201403371T 2014-06-18
PCT/SG2015/050166 WO2015195049A1 (fr) 2014-06-18 2015-06-17 Nouveaux promoteurs pour une expression de haut niveau
SG11201609879SA SG11201609879SA (en) 2014-06-18 2015-06-17 Novel promoters for high level expression

Publications (1)

Publication Number Publication Date
SG11201609879SA true SG11201609879SA (en) 2016-12-29

Family

ID=54935884

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201609879SA SG11201609879SA (en) 2014-06-18 2015-06-17 Novel promoters for high level expression

Country Status (4)

Country Link
US (1) US10563222B2 (fr)
CN (1) CN106459999A (fr)
SG (1) SG11201609879SA (fr)
WO (1) WO2015195049A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109988759A (zh) * 2017-12-29 2019-07-09 上海细胞治疗研究院 一种在t细胞中具有高转录活性的嵌合启动子
WO2020034097A1 (fr) * 2018-08-14 2020-02-20 Wuxi Biologics (Shanghai) Co., Ltd. Élément régulateur transcriptionnel et son utilisation dans l'amélioration de l'expression de protéine exogène
EP3864138A4 (fr) * 2018-10-10 2022-10-26 The Regents Of The University Of California Compositions et procédés pour modifier des lymphocytes t régulateurs
WO2022081776A1 (fr) * 2020-10-13 2022-04-21 Kriya Therapeutics, Inc. Constructions de vecteurs viraux pour l'apport d'acides nucléiques codant pour des cytokines et leurs utilisations pour le traitement du cancer
WO2022192687A1 (fr) * 2021-03-12 2022-09-15 University Of Massachusetts Promoteurs synthétiques pour thérapie génique et expression protéique

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003267967B2 (en) * 2002-06-18 2008-11-20 Zymogenetics, Inc. Hybrid vector having a cytomegalovirus enhancer and myeloproliferative sarcoma virus promoter
PT1685251E (pt) * 2003-10-10 2014-04-15 Powderject Vaccines Inc Construções de ácido nucleico
CA2566355C (fr) * 2004-05-18 2014-04-15 Vical Incorporated Composition de vaccin contre le virus de la grippe et ses methodes d'utilisation
US8377653B2 (en) * 2005-02-11 2013-02-19 Icosagen Cell Factory Oü Viral expression plasmids for production of proteins, antibodies, enzymes, virus-like particles and for use in cell-based assays
BRPI0720813A2 (pt) * 2007-01-25 2013-03-19 Amprotein Corp vetor de expressço para ser utilizado na produÇço recombinante de um polipeptideo em uma cÉlula de mamÍfero, mÉtodo para a produÇço recombianate de um polipeptÍdeo, mÉtodo para melhorar eficÁcia de um vetor de expressço do gene e mÉtodo para intensificar o desempenho de um vetor de expressço existente
KR101103650B1 (ko) * 2007-10-10 2012-01-11 한국생명공학연구원 동물세포에서의 단백질 고발현 벡터 시스템
WO2010072676A1 (fr) * 2008-12-22 2010-07-01 Lek Pharmaceuticals D.D. Vecteur d'expression de mammifère
KR101038126B1 (ko) * 2010-11-30 2011-05-31 주식회사 엘지생명과학 새로운 융합 프로모터 및 이를 포함하는 재조합 벡터
US9114108B2 (en) * 2011-11-30 2015-08-25 Merial, Inc. Recombinant HVT vectors expressing antigens of avian pathogens and uses thereof
WO2014133468A1 (fr) * 2013-02-28 2014-09-04 Agency For Science, Technology And Research Promoteurs chimères pour un niveau et une stabilité d'expression génique élevés dans des cellules mammifères
EP2964768B1 (fr) * 2013-03-08 2020-07-22 Neuclone Biologics Pty Ltd Système d'expression cellulaire

Also Published As

Publication number Publication date
CN106459999A (zh) 2017-02-22
US10563222B2 (en) 2020-02-18
US20170130244A1 (en) 2017-05-11
WO2015195049A1 (fr) 2015-12-23

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