SG11201609879SA - Novel promoters for high level expression - Google Patents

Novel promoters for high level expression

Info

Publication number
SG11201609879SA
SG11201609879SA SG11201609879SA SG11201609879SA SG11201609879SA SG 11201609879S A SG11201609879S A SG 11201609879SA SG 11201609879S A SG11201609879S A SG 11201609879SA SG 11201609879S A SG11201609879S A SG 11201609879SA SG 11201609879S A SG11201609879S A SG 11201609879SA
Authority
SG
Singapore
Prior art keywords
high level
level expression
novel promoters
promoters
novel
Prior art date
Application number
SG11201609879SA
Inventor
Yuansheng Yang
Cheng Leong Steven Ho
Fang Shiyi Goh
Original Assignee
Agency Science Tech & Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency Science Tech & Res filed Critical Agency Science Tech & Res
Priority to SG11201609879SA priority Critical patent/SG11201609879SA/en
Publication of SG11201609879SA publication Critical patent/SG11201609879SA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/15—Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/60—Vector systems having a special element relevant for transcription from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/90—Vector systems having a special element relevant for transcription from vertebrates avian

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SG11201609879SA 2014-06-18 2015-06-17 Novel promoters for high level expression SG11201609879SA (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SG11201609879SA SG11201609879SA (en) 2014-06-18 2015-06-17 Novel promoters for high level expression

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SG10201403371T 2014-06-18
SG11201609879SA SG11201609879SA (en) 2014-06-18 2015-06-17 Novel promoters for high level expression
PCT/SG2015/050166 WO2015195049A1 (en) 2014-06-18 2015-06-17 Novel promoters for high level expression

Publications (1)

Publication Number Publication Date
SG11201609879SA true SG11201609879SA (en) 2016-12-29

Family

ID=54935884

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201609879SA SG11201609879SA (en) 2014-06-18 2015-06-17 Novel promoters for high level expression

Country Status (4)

Country Link
US (1) US10563222B2 (en)
CN (1) CN106459999A (en)
SG (1) SG11201609879SA (en)
WO (1) WO2015195049A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109988759A (en) * 2017-12-29 2019-07-09 上海细胞治疗研究院 A kind of chimeric promoters in T cell with high transcriptional activity
WO2020034097A1 (en) * 2018-08-14 2020-02-20 Wuxi Biologics (Shanghai) Co., Ltd. Transcriptional regulatory element and its use in enhancing the expression of exogenous protein
WO2020077110A1 (en) * 2018-10-10 2020-04-16 The Regents Of The University Of California Compositions and methods for modifying regulatory t cells
WO2022081776A1 (en) * 2020-10-13 2022-04-21 Kriya Therapeutics, Inc. Viral vector constructs for delivery of nucleic acids encoding cytokines and uses thereof for treating cancer
US20240043872A1 (en) * 2021-03-12 2024-02-08 University Of Massachusetts Synthetic promoters for gene therapy and protein expression

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2488924A1 (en) * 2002-06-18 2003-12-24 Zymogenetics, Inc. Hybrid vector having a cytomegalovirus enhancer and myeloproliferative sarcoma virus promoter
KR101234981B1 (en) * 2003-10-10 2013-02-21 파우더젝트 백신, 인코포레이티드 Nucleic Acid Constructs
JP5331340B2 (en) * 2004-05-18 2013-10-30 バイカル インコーポレイテッド Influenza virus vaccine composition and method of use thereof
US8377653B2 (en) * 2005-02-11 2013-02-19 Icosagen Cell Factory Oü Viral expression plasmids for production of proteins, antibodies, enzymes, virus-like particles and for use in cell-based assays
KR20100038280A (en) * 2007-01-25 2010-04-14 앰프로틴 코포레이션 Use of chick beta actin gene intron-1
KR101103650B1 (en) * 2007-10-10 2012-01-11 한국생명공학연구원 The vector system for high expression of proteins in mammalian cells
CA2745311C (en) * 2008-12-22 2020-08-18 Lek Pharmaceuticals D.D. Mammalian expression vector comprising human beta globin intronii
KR101038126B1 (en) * 2010-11-30 2011-05-31 주식회사 엘지생명과학 Novel hybrid promoter and recombinant vector which includes the promoter
US9114108B2 (en) * 2011-11-30 2015-08-25 Merial, Inc. Recombinant HVT vectors expressing antigens of avian pathogens and uses thereof
WO2014133468A1 (en) * 2013-02-28 2014-09-04 Agency For Science, Technology And Research Chimeric promoters for high gene expression level and stability in mammalian cells
US9404078B2 (en) * 2013-03-08 2016-08-02 Neuclone Biologics Pty Ltd Cell expression system

Also Published As

Publication number Publication date
WO2015195049A1 (en) 2015-12-23
US20170130244A1 (en) 2017-05-11
US10563222B2 (en) 2020-02-18
CN106459999A (en) 2017-02-22

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