SG11201607693WA - 6-substituted estradiol derivatives for the treatment of alzheimer's disease - Google Patents

6-substituted estradiol derivatives for the treatment of alzheimer's disease

Info

Publication number
SG11201607693WA
SG11201607693WA SG11201607693WA SG11201607693WA SG11201607693WA SG 11201607693W A SG11201607693W A SG 11201607693WA SG 11201607693W A SG11201607693W A SG 11201607693WA SG 11201607693W A SG11201607693W A SG 11201607693WA SG 11201607693W A SG11201607693W A SG 11201607693WA
Authority
SG
Singapore
Prior art keywords
alzheimer
disease
treatment
estradiol derivatives
substituted estradiol
Prior art date
Application number
SG11201607693WA
Other languages
English (en)
Inventor
James G Yarger
Steven H Nye
Original Assignee
Endece Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Endece Llc filed Critical Endece Llc
Publication of SG11201607693WA publication Critical patent/SG11201607693WA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
SG11201607693WA 2014-03-19 2015-03-19 6-substituted estradiol derivatives for the treatment of alzheimer's disease SG11201607693WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461955578P 2014-03-19 2014-03-19
PCT/US2015/021538 WO2015143201A2 (en) 2014-03-19 2015-03-19 6-substituted estradiol derivatives for the treatment of alzheimer's disease

Publications (1)

Publication Number Publication Date
SG11201607693WA true SG11201607693WA (en) 2016-10-28

Family

ID=54141046

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201607693WA SG11201607693WA (en) 2014-03-19 2015-03-19 6-substituted estradiol derivatives for the treatment of alzheimer's disease

Country Status (11)

Country Link
US (1) US20150265630A1 (cg-RX-API-DMAC7.html)
EP (1) EP3119402A4 (cg-RX-API-DMAC7.html)
JP (1) JP2017512769A (cg-RX-API-DMAC7.html)
KR (1) KR20160136363A (cg-RX-API-DMAC7.html)
CN (1) CN106255501A (cg-RX-API-DMAC7.html)
AU (2) AU2015231172A1 (cg-RX-API-DMAC7.html)
BR (1) BR112016021408A2 (cg-RX-API-DMAC7.html)
CA (1) CA2940536A1 (cg-RX-API-DMAC7.html)
MX (1) MX2016012045A (cg-RX-API-DMAC7.html)
SG (1) SG11201607693WA (cg-RX-API-DMAC7.html)
WO (1) WO2015143201A2 (cg-RX-API-DMAC7.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102719543B1 (ko) * 2019-06-03 2024-10-17 아이홀 코포레이션 히알루로난 접합체 및 이의 용도
US20210024568A1 (en) * 2019-07-23 2021-01-28 Endece Llc Methods for modulation of lipoprotein lipase and apolipoprotein c2 expression and/or activity in the treatment of peripheral and central nervous system tissue disease states

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10174070B2 (en) * 2005-09-30 2019-01-08 Endece Llc 6-substituted estradiol derivatives and methods of use
WO2008100560A2 (en) * 2007-02-14 2008-08-21 University Of Southern California Estrogen receptor modulators, associated pharmaceutical compositions and methods of use
WO2012129324A2 (en) * 2011-03-21 2012-09-27 Endece Llc 6-substituted estradiol derivatives for use in remyelination of nerve axons

Also Published As

Publication number Publication date
BR112016021408A2 (pt) 2017-12-19
AU2015231172A1 (en) 2016-09-08
EP3119402A4 (en) 2017-11-01
KR20160136363A (ko) 2016-11-29
AU2018201003A1 (en) 2018-03-01
CA2940536A1 (en) 2015-09-24
JP2017512769A (ja) 2017-05-25
CN106255501A (zh) 2016-12-21
US20150265630A1 (en) 2015-09-24
EP3119402A2 (en) 2017-01-25
MX2016012045A (es) 2017-01-19
WO2015143201A2 (en) 2015-09-24

Similar Documents

Publication Publication Date Title
IL285722A (en) Methods for treating Alzheimer's disease
IL280530A (en) Decarboxylase aromatic amino acid-encoding phylonucleotides for the treatment of Parkinson's disease
ZA201608108B (en) Huntington's disease therapeutic compounds
IL247085B (en) Methods for treating Alzheimer's disease
EP3268086A4 (en) Lsd for the treatment of alzheimer's disease
ZA201605341B (en) Methods of treating alzheimer's disease
IL249502B (en) New therapeutic uses of benzylideneguanidine derivatives for the treatment of diseases caused by structurally abnormal proteins
IL263188B (en) Treatment for Parkinson's disease
IL254252A0 (en) History of Tetrahydrofuran-Oahe Aminohydrothiazine Usefulness in the Treatment of Alzheimer's Disease
SG11201607693WA (en) 6-substituted estradiol derivatives for the treatment of alzheimer's disease
EP3244897A4 (en) Methods for treating alzheimer's disease
PT3119752T (pt) Compostos 3,4-diamino-6-cloropirazina-2-carboxamida para o tratamento de doenças mediadas por enac
DK3148588T3 (en) N,n-bis-2-mercaptoethyl isophthalamide for the treatment of parkinson's disease
ZA201807944B (en) Treatment for parkinson's disease
GB201511453D0 (en) Treatment of alzheimer's disease
GB201414038D0 (en) Alzheimer's disease
EP3122356A4 (en) Treatment of parkinson's disease through arfgap1 inhibition using substituted piperazine derivatives