SG11201606843SA - Fusion genes in cancer - Google Patents

Fusion genes in cancer

Info

Publication number
SG11201606843SA
SG11201606843SA SG11201606843SA SG11201606843SA SG11201606843SA SG 11201606843S A SG11201606843S A SG 11201606843SA SG 11201606843S A SG11201606843S A SG 11201606843SA SG 11201606843S A SG11201606843S A SG 11201606843SA SG 11201606843S A SG11201606843S A SG 11201606843SA
Authority
SG
Singapore
Prior art keywords
cancer
fusion genes
genes
fusion
Prior art date
Application number
SG11201606843SA
Other languages
English (en)
Inventor
Axel Hillmer
Yijun Ruan
Fei Yao
Patrick Tan
Khay Guan Yeoh
Walter Hunziker
Audrey S M Teo
Yee Yen Sia
Original Assignee
Agency Science Tech & Res
Univ Singapore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency Science Tech & Res, Univ Singapore filed Critical Agency Science Tech & Res
Priority to SG11201606843SA priority Critical patent/SG11201606843SA/en
Publication of SG11201606843SA publication Critical patent/SG11201606843SA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
SG11201606843SA 2014-03-21 2015-03-23 Fusion genes in cancer SG11201606843SA (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SG11201606843SA SG11201606843SA (en) 2014-03-21 2015-03-23 Fusion genes in cancer

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SG10201400876T 2014-03-21
SG11201606843SA SG11201606843SA (en) 2014-03-21 2015-03-23 Fusion genes in cancer
PCT/SG2015/050047 WO2015142293A1 (fr) 2014-03-21 2015-03-23 Gènes de fusion dans le cancer

Publications (1)

Publication Number Publication Date
SG11201606843SA true SG11201606843SA (en) 2016-10-28

Family

ID=54145081

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201606843SA SG11201606843SA (en) 2014-03-21 2015-03-23 Fusion genes in cancer

Country Status (6)

Country Link
US (1) US20170081723A1 (fr)
EP (1) EP3119912A4 (fr)
JP (1) JP2017514514A (fr)
CN (1) CN106460054A (fr)
SG (1) SG11201606843SA (fr)
WO (1) WO2015142293A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3342863B1 (fr) 2015-08-24 2020-03-25 Astellas Pharma Inc. Procédé de détection du gène de fusion rp2-arhgap6
EP3342862B1 (fr) * 2015-08-24 2020-03-25 Astellas Pharma Inc. Procédé de détection du gène de fusion ocln-arhgap26
EP3498835A4 (fr) 2016-08-10 2020-03-18 Astellas Pharma Inc. Procédé de détection de gène hybride cldn18-arhgap6 ou de gène hybride cldn18-arhgap26 du cancer du pancréas
CN106434953B (zh) * 2016-10-27 2019-11-22 宁波大学 一种胃癌新型分子标记物hsa_circ_0074362的检测及应用
KR101996141B1 (ko) * 2017-09-21 2019-07-03 건국대학교 산학협력단 Bcar4 엑손 4 또는 이를 포함하는 융합 유전자를 이용하는 종양 진단용 조성물
JP2022527277A (ja) * 2019-03-26 2022-06-01 ザ・ペン・ステイト・リサーチ・ファウンデイション がんを処置するための方法及び材料
WO2022114957A1 (fr) * 2020-11-26 2022-06-02 Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Marqueurs tumoraux personnalisés
CN115920053A (zh) * 2022-12-23 2023-04-07 河北医科大学第四医院 Crx在肺癌诊断、治疗中的应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ562237A (en) * 2007-10-05 2011-02-25 Pacific Edge Biotechnology Ltd Proliferation signature and prognosis for gastrointestinal cancer
EP2212435A4 (fr) * 2007-10-22 2010-11-03 Agency Science Tech & Res Gène(s) fusionné(s)
RU2016131167A (ru) * 2009-10-07 2018-12-07 Дженентек, Инк. Способы лечения, диагностики и мониторинга волчанки
US20120258998A1 (en) * 2011-04-05 2012-10-11 Patrick Tan Fusion genes in gastrointestinal cancer
US20140296181A1 (en) * 2011-04-07 2014-10-02 Coferon, Inc. Methods of modulating oncogenic fusion proteins
CA2759516C (fr) * 2011-11-24 2019-12-31 Ibm Canada Limited - Ibm Canada Limitee Serialisation d'objets preinitialises
US20130096021A1 (en) * 2011-09-27 2013-04-18 Arul M. Chinnaiyan Recurrent gene fusions in breast cancer
EP2812354A4 (fr) * 2012-02-06 2016-03-09 Univ California Régulation de l'angiogenèse par emp2 dans les cellules cancéreuses par le biais de l'induction de vegf
WO2013174403A1 (fr) * 2012-05-23 2013-11-28 Ganymed Pharmaceuticals Ag Polythérapie impliquant des anticorps dirigés contre la claudine 18,2 pour le traitement du cancer
US10169530B2 (en) * 2012-11-05 2019-01-01 Genomic Health, Inc. Gene fusions and alternatively spliced junctions associated with breast cancer
CN102993314B (zh) * 2012-12-24 2014-04-30 河北大学 一种抗肿瘤融合蛋白及其制备方法和用途

Also Published As

Publication number Publication date
US20170081723A1 (en) 2017-03-23
EP3119912A1 (fr) 2017-01-25
CN106460054A (zh) 2017-02-22
WO2015142293A1 (fr) 2015-09-24
EP3119912A4 (fr) 2018-02-14
JP2017514514A (ja) 2017-06-08

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