SG11201606843SA - Fusion genes in cancer - Google Patents

Fusion genes in cancer

Info

Publication number
SG11201606843SA
SG11201606843SA SG11201606843SA SG11201606843SA SG11201606843SA SG 11201606843S A SG11201606843S A SG 11201606843SA SG 11201606843S A SG11201606843S A SG 11201606843SA SG 11201606843S A SG11201606843S A SG 11201606843SA SG 11201606843S A SG11201606843S A SG 11201606843SA
Authority
SG
Singapore
Prior art keywords
cancer
fusion genes
genes
fusion
Prior art date
Application number
SG11201606843SA
Inventor
Axel Hillmer
Yijun Ruan
Fei Yao
Patrick Tan
Khay Guan Yeoh
Walter Hunziker
Audrey S M Teo
Yee Yen Sia
Original Assignee
Agency Science Tech & Res
Univ Singapore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency Science Tech & Res, Univ Singapore filed Critical Agency Science Tech & Res
Priority to SG11201606843SA priority Critical patent/SG11201606843SA/en
Publication of SG11201606843SA publication Critical patent/SG11201606843SA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
SG11201606843SA 2014-03-21 2015-03-23 Fusion genes in cancer SG11201606843SA (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SG11201606843SA SG11201606843SA (en) 2014-03-21 2015-03-23 Fusion genes in cancer

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SG10201400876T 2014-03-21
SG11201606843SA SG11201606843SA (en) 2014-03-21 2015-03-23 Fusion genes in cancer
PCT/SG2015/050047 WO2015142293A1 (en) 2014-03-21 2015-03-23 Fusion genes in cancer

Publications (1)

Publication Number Publication Date
SG11201606843SA true SG11201606843SA (en) 2016-10-28

Family

ID=54145081

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201606843SA SG11201606843SA (en) 2014-03-21 2015-03-23 Fusion genes in cancer

Country Status (6)

Country Link
US (1) US20170081723A1 (en)
EP (1) EP3119912A4 (en)
JP (1) JP2017514514A (en)
CN (1) CN106460054A (en)
SG (1) SG11201606843SA (en)
WO (1) WO2015142293A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6762539B2 (en) 2015-08-24 2020-09-30 アステラス製薬株式会社 Method for detecting OCRN-ARHGAP26 gene
JP6762540B2 (en) * 2015-08-24 2020-09-30 アステラス製薬株式会社 Method for detecting the RP2-ARHGAP6 gene
US11053553B2 (en) 2016-08-10 2021-07-06 Astellas Pharma Inc. Detection of CLDN18-ARHGAP6 fusion gene or CLDN18-ARHGAP26 fusion gene in pancreatic cancer
CN106434953B (en) * 2016-10-27 2019-11-22 宁波大学 A kind of detection and application of gastric cancer New molecular marker object hsa_circ_0074362
KR101996141B1 (en) * 2017-09-21 2019-07-03 건국대학교 산학협력단 Composition for diagnosing tumor using BCAR4 exon 4 or its fusion gene thereof
WO2020198485A1 (en) * 2019-03-26 2020-10-01 The Penn State Research Foundation Methods and materials for treating cancer
WO2022114957A1 (en) * 2020-11-26 2022-06-02 Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Personalized tumor markers
CN115920053A (en) * 2022-12-23 2023-04-07 河北医科大学第四医院 Application of CRX in diagnosis and treatment of lung cancer

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ562237A (en) * 2007-10-05 2011-02-25 Pacific Edge Biotechnology Ltd Proliferation signature and prognosis for gastrointestinal cancer
US20100285475A1 (en) * 2007-10-22 2010-11-11 Agency For Science, Technology And Research Fused genes
KR101824744B1 (en) * 2009-10-07 2018-03-15 제넨테크, 인크. Methods for treating, diagnosing, and monitoring lupus
US20120258998A1 (en) * 2011-04-05 2012-10-11 Patrick Tan Fusion genes in gastrointestinal cancer
US20140296181A1 (en) * 2011-04-07 2014-10-02 Coferon, Inc. Methods of modulating oncogenic fusion proteins
CA2759516C (en) * 2011-11-24 2019-12-31 Ibm Canada Limited - Ibm Canada Limitee Serialization of pre-initialized objects
WO2013089882A2 (en) * 2011-09-27 2013-06-20 The Regents Of The University Of Michigan Recurrent gene fusions in breast cancer
EP2812354A4 (en) * 2012-02-06 2016-03-09 Univ California Emp2 regulates angiogenesis in cancer cells through induction of vegf
WO2013174403A1 (en) * 2012-05-23 2013-11-28 Ganymed Pharmaceuticals Ag Combination therapy involving antibodies against claudin 18.2 for treatment of cancer
US10169530B2 (en) * 2012-11-05 2019-01-01 Genomic Health, Inc. Gene fusions and alternatively spliced junctions associated with breast cancer
CN102993314B (en) * 2012-12-24 2014-04-30 河北大学 Anti-tumor fusion protein, as well as preparation method and application thereof

Also Published As

Publication number Publication date
EP3119912A1 (en) 2017-01-25
WO2015142293A1 (en) 2015-09-24
EP3119912A4 (en) 2018-02-14
CN106460054A (en) 2017-02-22
US20170081723A1 (en) 2017-03-23
JP2017514514A (en) 2017-06-08

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