SG11201606163QA - Novel full spectrum anti-dengue antibody - Google Patents

Novel full spectrum anti-dengue antibody

Info

Publication number
SG11201606163QA
SG11201606163QA SG11201606163QA SG11201606163QA SG11201606163QA SG 11201606163Q A SG11201606163Q A SG 11201606163QA SG 11201606163Q A SG11201606163Q A SG 11201606163QA SG 11201606163Q A SG11201606163Q A SG 11201606163QA SG 11201606163Q A SG11201606163Q A SG 11201606163QA
Authority
SG
Singapore
Prior art keywords
full spectrum
novel full
spectrum anti
dengue antibody
dengue
Prior art date
Application number
SG11201606163QA
Other languages
English (en)
Inventor
Ram Sasisekharan
Kannan Tharakaraman
Original Assignee
Massachusetts Inst Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology filed Critical Massachusetts Inst Technology
Publication of SG11201606163QA publication Critical patent/SG11201606163QA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1081Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11201606163QA 2014-02-11 2015-02-11 Novel full spectrum anti-dengue antibody SG11201606163QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461938605P 2014-02-11 2014-02-11
PCT/US2015/015510 WO2015123362A1 (fr) 2014-02-11 2015-02-11 Nouveaux anticorps anti-dengue à spectre complet

Publications (1)

Publication Number Publication Date
SG11201606163QA true SG11201606163QA (en) 2016-08-30

Family

ID=53800606

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201807826XA SG10201807826XA (en) 2014-02-11 2015-02-11 Novel full spectrum anti-dengue antibody
SG11201606163QA SG11201606163QA (en) 2014-02-11 2015-02-11 Novel full spectrum anti-dengue antibody

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10201807826XA SG10201807826XA (en) 2014-02-11 2015-02-11 Novel full spectrum anti-dengue antibody

Country Status (12)

Country Link
US (3) US9902764B2 (fr)
EP (1) EP3104888A4 (fr)
JP (1) JP6707455B2 (fr)
KR (1) KR20160119806A (fr)
CN (1) CN106413749B (fr)
AU (1) AU2015217149B2 (fr)
BR (1) BR112016017764A2 (fr)
CA (1) CA2938495A1 (fr)
IL (1) IL246788A0 (fr)
MX (1) MX2016009991A (fr)
SG (2) SG10201807826XA (fr)
WO (1) WO2015123362A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2194066B1 (fr) 2007-09-26 2016-03-09 Chugai Seiyaku Kabushiki Kaisha Région constante d'anticorps modifiée
WO2014025546A2 (fr) 2012-08-07 2014-02-13 Massachusetts Institute Of Technology Anticorps anti-virus de la dengue (denv) et leurs utilisations
ES2900749T3 (es) 2014-02-11 2022-03-18 Visterra Inc Moléculas de anticuerpos contra el virus del dengue y usos de las mismas
SG10201807826XA (en) 2014-02-11 2018-10-30 Massachusetts Inst Technology Novel full spectrum anti-dengue antibody
MX2017008978A (es) 2015-02-05 2017-10-25 Chugai Pharmaceutical Co Ltd Anticuerpos que comprenden un dominio de union al antigeno dependiente de la concentracion ionica, variantes de la region fc, antiocuerpor de union a interleucina 8 (il-8) y usos de los mismos.
CN109311986A (zh) 2016-03-25 2019-02-05 威特拉公司 登革热病毒抗体分子的制剂
EP3494991A4 (fr) 2016-08-05 2020-07-29 Chugai Seiyaku Kabushiki Kaisha Composition pour la prophylaxie ou le traitement de maladies liées à il-8
SG10201607778XA (en) 2016-09-16 2018-04-27 Chugai Pharmaceutical Co Ltd Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use
JP2022008719A (ja) * 2016-11-23 2022-01-14 セルヴァス エーアイ インコーポレイテッド 疾患発症予測方法及び装置
BR112019011900A2 (pt) 2016-12-23 2019-11-26 Serum Institute Of India Private Limited métodos melhorados para aumentar a produtividade de anticorpos na cultura de células de mamíferos e minimizar a agregação durante os processos downs-tream, processos de formulação, e formulações de anticorpos estáveis obtidas dos mesmos
KR20200132938A (ko) 2018-03-15 2020-11-25 추가이 세이야쿠 가부시키가이샤 지카 바이러스에 대해 교차-반응성을 갖는 항-뎅기 바이러스 항체 및 사용 방법

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US4938948A (en) 1985-10-07 1990-07-03 Cetus Corporation Method for imaging breast tumors using labeled monoclonal anti-human breast cancer antibodies
US5750172A (en) 1987-06-23 1998-05-12 Pharming B.V. Transgenic non human mammal milk
US5633076A (en) 1989-12-01 1997-05-27 Pharming Bv Method of producing a transgenic bovine or transgenic bovine embryo
JPH049249A (ja) 1990-04-27 1992-01-14 Kusuda:Kk 塗型剤吹き付け機
ES2146648T3 (es) 1993-03-09 2000-08-16 Genzyme Corp Procedimiento de aislamiento de proteinas de la leche.
US5500161A (en) 1993-09-21 1996-03-19 Massachusetts Institute Of Technology And Virus Research Institute Method for making hydrophobic polymeric microparticles
US5827690A (en) 1993-12-20 1998-10-27 Genzyme Transgenics Corporatiion Transgenic production of antibodies in milk
JPH07299655A (ja) 1994-04-30 1995-11-14 Aisin Seiki Co Ltd 内スプライン歯面仕上機
DE19742706B4 (de) 1997-09-26 2013-07-25 Pieris Proteolab Ag Lipocalinmuteine
WO2003029471A1 (fr) 2001-09-27 2003-04-10 Pieris Proteolab Ag Muteines d'apolipoproteine d
WO2003029462A1 (fr) 2001-09-27 2003-04-10 Pieris Proteolab Ag Muteines de la lipocaline neutrophile humaine associee a la gelatinase et de proteines apparentees
WO2003080672A1 (fr) 2002-03-22 2003-10-02 Aprogen, Inc. Anticorps humanise et procede de preparation correspondant
US7232888B2 (en) 2002-07-01 2007-06-19 Massachusetts Institute Of Technology Antibodies against tumor surface antigens
EP1556477B1 (fr) 2002-11-01 2017-08-09 GlaxoSmithKline Biologicals s.a. Sechage
US7622113B2 (en) * 2003-12-08 2009-11-24 The United States Of America As Represented By The Department Of Health And Human Services Monoclonal antibodies that bind or neutralize dengue virus
EP1814988A2 (fr) 2004-11-26 2007-08-08 Pieris AG Compose a affinite pour l'antigene associe au lymphocyte t cytotoxique (ctla-4)
AU2006280144B2 (en) * 2005-08-10 2012-06-14 Sanofi Pasteur Biologics, Llc Vaccination against dengue virus infection
CU23586A1 (es) 2005-11-22 2010-10-30 Ct Ingenieria Genetica Biotech Métodos y proteínas para el tratamiento profiláctico y/o terapéutico de los cuatro serotipos del virus de dengue y otros flavivirus
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EP2653545A1 (fr) 2008-02-05 2013-10-23 Bicycle Therapeutics Limited Procédés et compositions
BRPI0823197A2 (pt) * 2008-10-05 2015-06-23 Univ Leland Stanford Junior Anticorpos contra hepatite c e aplicações dos mesmos
JP5814790B2 (ja) * 2008-10-13 2015-11-17 インスティテュート・フォー・リサーチ・イン・バイオメディシンInstitute For Research In Biomedicine デングウイルス中和抗体およびその使用
CN102573905A (zh) 2008-12-05 2012-07-11 勒帕斯公司 利用抗脂类抗体晶体结构的抗体设计
WO2010093335A1 (fr) 2009-02-10 2010-08-19 Nanyang Technological University Anticorps destinés au diagnostic et au traitement d'infections flavivirales
EP2353609A1 (fr) 2010-02-04 2011-08-10 Sanofi Pasteur Compositions et procédés d'immunisation
US8637035B2 (en) * 2010-07-16 2014-01-28 Academia Sinica Anti-dengue virus antibodies
US20140349321A1 (en) 2011-12-16 2014-11-27 Agency For Science, Technology And Research Binding molecules against dengue virus and uses thereof
US9556254B2 (en) * 2012-05-14 2017-01-31 The Usa, As Represented By The Secretary, Dept. Of Health And Human Services Cross-reactive antibodies against dengue virus and uses thereof
WO2014025546A2 (fr) 2012-08-07 2014-02-13 Massachusetts Institute Of Technology Anticorps anti-virus de la dengue (denv) et leurs utilisations
ES2900749T3 (es) 2014-02-11 2022-03-18 Visterra Inc Moléculas de anticuerpos contra el virus del dengue y usos de las mismas
SG10201807826XA (en) 2014-02-11 2018-10-30 Massachusetts Inst Technology Novel full spectrum anti-dengue antibody

Also Published As

Publication number Publication date
US20200207841A1 (en) 2020-07-02
IL246788A0 (en) 2016-08-31
AU2015217149B2 (en) 2020-09-10
US9902764B2 (en) 2018-02-27
JP6707455B2 (ja) 2020-06-10
US20150368321A1 (en) 2015-12-24
CN106413749A (zh) 2017-02-15
EP3104888A1 (fr) 2016-12-21
SG10201807826XA (en) 2018-10-30
EP3104888A4 (fr) 2017-08-09
US11421018B2 (en) 2022-08-23
CA2938495A1 (fr) 2015-08-20
AU2015217149A1 (en) 2016-09-08
JP2017507131A (ja) 2017-03-16
WO2015123362A1 (fr) 2015-08-20
KR20160119806A (ko) 2016-10-14
CN106413749B (zh) 2022-04-05
US10519220B2 (en) 2019-12-31
MX2016009991A (es) 2016-10-07
US20180237504A1 (en) 2018-08-23
BR112016017764A2 (pt) 2017-10-10

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