SG11201603209XA - Gsk-3 inhibitors - Google Patents
Gsk-3 inhibitorsInfo
- Publication number
- SG11201603209XA SG11201603209XA SG11201603209XA SG11201603209XA SG11201603209XA SG 11201603209X A SG11201603209X A SG 11201603209XA SG 11201603209X A SG11201603209X A SG 11201603209XA SG 11201603209X A SG11201603209X A SG 11201603209XA SG 11201603209X A SG11201603209X A SG 11201603209XA
- Authority
- SG
- Singapore
- Prior art keywords
- gsk
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361900465P | 2013-11-06 | 2013-11-06 | |
PCT/US2014/063691 WO2015069594A1 (en) | 2013-11-06 | 2014-11-03 | Gsk-3 inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201603209XA true SG11201603209XA (en) | 2016-05-30 |
Family
ID=51982762
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201603209XA SG11201603209XA (en) | 2013-11-06 | 2014-11-03 | Gsk-3 inhibitors |
Country Status (12)
Country | Link |
---|---|
US (1) | US9718804B2 (ru) |
EP (1) | EP3066093B9 (ru) |
JP (1) | JP2016535755A (ru) |
KR (1) | KR102339227B1 (ru) |
CN (1) | CN105849098A (ru) |
AU (1) | AU2014347027A1 (ru) |
CA (1) | CA2929528A1 (ru) |
EA (1) | EA201690844A1 (ru) |
IL (1) | IL245442A0 (ru) |
MX (1) | MX2016005760A (ru) |
SG (1) | SG11201603209XA (ru) |
WO (1) | WO2015069594A1 (ru) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2929502A1 (en) | 2013-11-06 | 2015-05-14 | Bristol-Myers Squibb Company | Substituted pyridine derivatives useful as gsk-3 inhibitors |
ES2946001T3 (es) | 2016-10-26 | 2023-07-11 | Rigel Pharmaceuticals Inc | Compuestos de pirazol amida como inhibidores de IRAK |
CN110225912B (zh) * | 2016-11-28 | 2022-10-21 | 百时美施贵宝公司 | Gsk-3抑制剂 |
EP3544968B1 (en) * | 2016-11-28 | 2020-12-30 | Bristol-Myers Squibb Company | Pyrimidine carboxamides as gsk-3 inhibitors |
US10752609B2 (en) | 2016-11-28 | 2020-08-25 | Bristol-Myers Squibb Company | GSK-3 inhibitors |
JP7144863B2 (ja) | 2016-12-28 | 2022-09-30 | ミノリックス セラピューティクス エセ.エレ. | イソキノリン化合物、その調製の方法、およびベータガラクトシダーゼの活性の変質に伴う状態におけるその治療的使用 |
JP2020512976A (ja) * | 2017-03-27 | 2020-04-30 | ファーマケア,インク. | アポトーシスシグナル調節キナーゼ1(ask1)阻害剤化合物 |
IL305085A (en) | 2017-09-07 | 2023-10-01 | Univ Res Inst Inc Augusta | A specific AKT3 activator and its uses |
CA3117222A1 (en) | 2018-11-19 | 2020-05-28 | Amgen Inc. | Kras g12c inhibitors and methods of using the same |
EP3898616A1 (en) * | 2018-12-20 | 2021-10-27 | Amgen Inc. | Heteroaryl amides useful as kif18a inhibitors |
AU2020218366A1 (en) | 2019-02-08 | 2021-09-16 | Frequency Therapeutics, Inc. | Valproic acid compounds and Wnt agonists for treating ear disorders |
WO2021026101A1 (en) * | 2019-08-02 | 2021-02-11 | Amgen Inc. | Kif18a inhibitors |
CA3147272A1 (en) * | 2019-08-02 | 2021-02-11 | Amgen Inc. | Kif18a inhibitors |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6756385B2 (en) * | 2000-07-31 | 2004-06-29 | Pfizer Inc. | Imidazole derivatives |
CA2539314A1 (en) | 2003-09-19 | 2005-03-31 | F. Hoffmann-La Roche Ag | Thiazolopyridine derivatives as adenosine receptor ligands |
US7531556B2 (en) | 2004-04-28 | 2009-05-12 | Vertex Pharmaceuticals Incorporated | Compositions useful as inhibitors of rock and other protein kinases |
SE0401345D0 (sv) | 2004-05-25 | 2004-05-25 | Astrazeneca Ab | Therapeutic compounds: Pyridine as scaffold |
WO2007022305A2 (en) | 2005-08-16 | 2007-02-22 | Pharmacopeia, Inc. | 2-aminoimidazopyridines for treating neurodegenerative diseases |
US20100227858A1 (en) | 2007-07-09 | 2010-09-09 | Astrazeneca Ab | Trisubstituted pyrimidine derivatives for the treatment of proliferative diseases |
EA201001367A1 (ru) | 2008-02-27 | 2011-04-29 | Мерк Патент Гмбх | Производные карбоксамид-гетероарила для лечения диабета |
CN102336720B (zh) | 2011-03-02 | 2016-01-13 | 华中科技大学 | 2-氨基噻唑衍生物及制备方法和应用 |
EP2712862A1 (en) * | 2012-09-28 | 2014-04-02 | Splicos | New anti-invasive compounds |
CA2929502A1 (en) | 2013-11-06 | 2015-05-14 | Bristol-Myers Squibb Company | Substituted pyridine derivatives useful as gsk-3 inhibitors |
-
2014
- 2014-11-03 US US15/033,813 patent/US9718804B2/en active Active
- 2014-11-03 KR KR1020167014599A patent/KR102339227B1/ko active IP Right Grant
- 2014-11-03 JP JP2016528235A patent/JP2016535755A/ja active Pending
- 2014-11-03 EP EP14802990.3A patent/EP3066093B9/en active Active
- 2014-11-03 AU AU2014347027A patent/AU2014347027A1/en not_active Abandoned
- 2014-11-03 SG SG11201603209XA patent/SG11201603209XA/en unknown
- 2014-11-03 CN CN201480072336.7A patent/CN105849098A/zh active Pending
- 2014-11-03 CA CA2929528A patent/CA2929528A1/en not_active Abandoned
- 2014-11-03 EA EA201690844A patent/EA201690844A1/ru unknown
- 2014-11-03 MX MX2016005760A patent/MX2016005760A/es unknown
- 2014-11-03 WO PCT/US2014/063691 patent/WO2015069594A1/en active Application Filing
-
2016
- 2016-05-03 IL IL245442A patent/IL245442A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU2014347027A1 (en) | 2016-06-23 |
IL245442A0 (en) | 2016-06-30 |
EA201690844A1 (ru) | 2016-08-31 |
JP2016535755A (ja) | 2016-11-17 |
EP3066093B1 (en) | 2017-10-04 |
EP3066093A1 (en) | 2016-09-14 |
US9718804B2 (en) | 2017-08-01 |
US20160272621A1 (en) | 2016-09-22 |
EP3066093B9 (en) | 2018-02-07 |
CN105849098A (zh) | 2016-08-10 |
WO2015069594A1 (en) | 2015-05-14 |
KR102339227B1 (ko) | 2021-12-13 |
CA2929528A1 (en) | 2015-05-14 |
MX2016005760A (es) | 2016-07-18 |
KR20160078494A (ko) | 2016-07-04 |
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