SG11201602976XA - Method and system for sensing - Google Patents

Method and system for sensing

Info

Publication number
SG11201602976XA
SG11201602976XA SG11201602976XA SG11201602976XA SG11201602976XA SG 11201602976X A SG11201602976X A SG 11201602976XA SG 11201602976X A SG11201602976X A SG 11201602976XA SG 11201602976X A SG11201602976X A SG 11201602976XA SG 11201602976X A SG11201602976X A SG 11201602976XA
Authority
SG
Singapore
Prior art keywords
sensing
Prior art date
Application number
SG11201602976XA
Other languages
English (en)
Inventor
Fernando Patolsky
Le-Chang Hsiung
Vadim Krivitsky
Vladimir Naddaka
Original Assignee
Univ Ramot
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Ramot filed Critical Univ Ramot
Publication of SG11201602976XA publication Critical patent/SG11201602976XA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403Cells and electrode assemblies
    • G01N27/414Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
    • G01N27/4146Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS involving nanosized elements, e.g. nanotubes, nanowires
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • C12Q1/004Enzyme electrodes mediator-assisted
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3278Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction involving nanosized elements, e.g. nanogaps or nanoparticles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/70Mechanisms involved in disease identification
    • G01N2800/7057(Intracellular) signaling and trafficking pathways
    • G01N2800/7066Metabolic pathways

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Electrochemistry (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
SG11201602976XA 2013-10-22 2014-10-22 Method and system for sensing SG11201602976XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361893977P 2013-10-22 2013-10-22
PCT/IL2014/050921 WO2015059704A1 (en) 2013-10-22 2014-10-22 Method and system for sensing

Publications (1)

Publication Number Publication Date
SG11201602976XA true SG11201602976XA (en) 2016-05-30

Family

ID=51894171

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201602976XA SG11201602976XA (en) 2013-10-22 2014-10-22 Method and system for sensing

Country Status (10)

Country Link
US (2) US10274456B2 (enExample)
EP (1) EP3060675B1 (enExample)
JP (1) JP6609247B2 (enExample)
KR (1) KR20160072258A (enExample)
CN (1) CN106164286A (enExample)
AU (1) AU2014338510A1 (enExample)
CA (1) CA2927332A1 (enExample)
MX (1) MX2016005273A (enExample)
SG (1) SG11201602976XA (enExample)
WO (1) WO2015059704A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2016005273A (es) 2013-10-22 2017-01-05 Ramot At Tel-Aviv Univ Ltd Procedimiento y sistema de deteccion.
CN106999929A (zh) * 2014-09-11 2017-08-01 克忧公司 用于检测和量化分析物的系统和方法
EP3386911B1 (en) * 2015-12-09 2023-09-20 Ramot at Tel-Aviv University Ltd. Method and system for sensing by modified nanostructure
AU2017239168B2 (en) * 2016-03-21 2022-02-03 University Of South Australia Oxidant sensor
CN109477846B (zh) * 2016-06-10 2022-03-29 联合利华知识产权控股有限公司 包括装置的机器和相应的方法
JP2019526794A (ja) * 2016-08-22 2019-09-19 ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッドRamot At Tel Aviv University Ltd. 生物検体の検出のための方法およびシステム
EP3500168B1 (en) * 2016-08-22 2021-06-23 Ramot at Tel-Aviv University Ltd. System for subcutaneous bioanalyte sensing
WO2018178992A1 (en) 2017-03-29 2018-10-04 Ramot At Tel-Aviv University Ltd. Method and system for separating biomolecules from a mixture containing same
WO2018198008A1 (en) * 2017-04-24 2018-11-01 Abdolahad Mohammad In-situ microbubbles generation for ultrasonic biomedical applications
IL260058B (en) 2017-06-15 2020-06-30 Filanovsky Boris Electrochemical detection of peroxide-containing compounds
SG11201911855PA (en) 2017-06-15 2020-01-30 Univ Ramot Electrochemical detection of nitro-containing compounds
WO2018234896A1 (en) * 2017-06-20 2018-12-27 Abdolahad Mohammad Real-time and label free analyzer for in-vitro and in-vivo detecting the suspicious regions to cancer
US10786188B1 (en) * 2017-06-20 2020-09-29 Mohammad Abdolahad Real-time and label free analyzer for in-vitro and in-vivo detection of cancer
US11179077B2 (en) 2017-06-20 2021-11-23 Mohammad Abdolahad Apparatus for in-vivo measuring of H2O2 oxidation
JP6833079B2 (ja) * 2017-08-01 2021-02-24 イラミーナ インコーポレーテッド 電界効果センサ
AU2018320264B2 (en) 2017-08-21 2024-08-15 Ramot At Tel-Aviv University Ltd. Methods of diagnosing and treating lung cancer
TWI765209B (zh) * 2019-01-18 2022-05-21 國立陽明交通大學 用來偵測全細胞細菌之以場效電晶體為主的生物感測器以及包含生物感測器的生物感測器組
WO2021009559A1 (en) 2019-07-12 2021-01-21 Qulab Medical Ltd. Electrochemical fet sensor
CN111487107B (zh) * 2020-06-07 2022-12-09 黑龙江省农业科学院农产品质量安全研究所 一种用于食品安全检测的样本分级处理装置
TWI852718B (zh) * 2023-08-08 2024-08-11 國立清華大學 多病毒檢測裝置、系統及其使用方法

Family Cites Families (17)

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Publication number Priority date Publication date Assignee Title
DE2214442C3 (de) * 1972-03-24 1981-09-10 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur Überführung von Glucose in Gluconsäure
EP1342075B1 (en) 2000-12-11 2008-09-10 President And Fellows Of Harvard College Device contaning nanosensors for detecting an analyte and its method of manufacture
AU2003282548A1 (en) 2002-10-10 2004-05-04 Nanosys, Inc. Nano-chem-fet based biosensors
US7416911B2 (en) * 2003-06-24 2008-08-26 California Institute Of Technology Electrochemical method for attaching molecular and biomolecular structures to semiconductor microstructures and nanostructures
US20090299213A1 (en) * 2006-03-15 2009-12-03 President And Fellows Of Harvard College Nanobioelectronics
WO2008030395A1 (en) * 2006-09-07 2008-03-13 California Institute Of Technology Apparatus and method for quantitative determination of target molecules
CN101679018A (zh) 2007-01-12 2010-03-24 环境生物技术Crc控股有限公司 试样处理装置
IL189576A0 (en) 2008-02-18 2008-12-29 Technion Res & Dev Foundation Chemically sensitive field effect transistors for explosive detection
US20110210309A1 (en) 2008-11-04 2011-09-01 Ramot At Tel-Aviv University Ltd. Tubular nanostructures, processes of preparing same and devices made therefrom
WO2010065967A2 (en) 2008-12-05 2010-06-10 Nanoivd, Inc. Microfluidic-based lab-on-a-test card for a point-of-care analyzer
WO2010115143A1 (en) 2009-04-03 2010-10-07 University Of Southern California Surface modification of nanosensor platforms to increase sensitivity and reproducibility
GB2471470A (en) 2009-06-30 2011-01-05 Hewlett Packard Development Co Quantum repeater and system and method for creating extended entanglements utilising cyclic synchronised control signals at repeater relay nodes
DE102010002915B4 (de) * 2010-03-16 2012-10-18 Senslab-Gesellschaft Zur Entwicklung Und Herstellung Bioelektrochemischer Sensoren Mbh Mikrofluidischer Sensor
WO2012082494A2 (en) * 2010-12-14 2012-06-21 Morehouse School Of Medicine The use of anti-cxcl13 and anti-cxcr5 antibodies for the treatment or detection of cancer
AU2012240953B2 (en) 2011-04-06 2017-02-23 Ramot At Tel-Aviv University Ltd. Methods of monitoring and analyzing metabolic activity profiles diagnostic and therapeutic uses of same
MX2016005273A (es) 2013-10-22 2017-01-05 Ramot At Tel-Aviv Univ Ltd Procedimiento y sistema de deteccion.
EP3386911B1 (en) 2015-12-09 2023-09-20 Ramot at Tel-Aviv University Ltd. Method and system for sensing by modified nanostructure

Also Published As

Publication number Publication date
EP3060675A1 (en) 2016-08-31
MX2016005273A (es) 2017-01-05
HK1225414B (en) 2017-09-08
AU2014338510A1 (en) 2016-06-09
KR20160072258A (ko) 2016-06-22
WO2015059704A1 (en) 2015-04-30
US20190234900A1 (en) 2019-08-01
CN106164286A (zh) 2016-11-23
EP3060675B1 (en) 2019-01-30
US20160258899A1 (en) 2016-09-08
US10274456B2 (en) 2019-04-30
CA2927332A1 (en) 2015-04-30
JP6609247B2 (ja) 2019-11-20
JP2016535988A (ja) 2016-11-24

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