SG11201602879UA - Exosome recovery methods with low molecular weight organic zwitterions - Google Patents

Exosome recovery methods with low molecular weight organic zwitterions

Info

Publication number
SG11201602879UA
SG11201602879UA SG11201602879UA SG11201602879UA SG11201602879UA SG 11201602879U A SG11201602879U A SG 11201602879UA SG 11201602879U A SG11201602879U A SG 11201602879UA SG 11201602879U A SG11201602879U A SG 11201602879UA SG 11201602879U A SG11201602879U A SG 11201602879UA
Authority
SG
Singapore
Prior art keywords
molecular weight
low molecular
weight organic
recovery methods
organic zwitterions
Prior art date
Application number
SG11201602879UA
Other languages
English (en)
Inventor
Peter Stanley Gagnon
Original Assignee
Agency Science Tech & Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency Science Tech & Res filed Critical Agency Science Tech & Res
Publication of SG11201602879UA publication Critical patent/SG11201602879UA/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5076—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving cell organelles, e.g. Golgi complex, endoplasmic reticulum
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
    • B01D15/361—Ion-exchange
    • B01D15/364—Amphoteric or zwitterionic ion-exchanger
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D35/00—Filtering devices having features not specifically covered by groups B01D24/00 - B01D33/00, or for applications not specifically covered by groups B01D24/00 - B01D33/00; Auxiliary devices for filtration; Filter housing constructions
    • B01D35/02—Filters adapted for location in special places, e.g. pipe-lines, pumps, stop-cocks
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B1/00—Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Developmental Biology & Embryology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SG11201602879UA 2013-10-24 2014-10-15 Exosome recovery methods with low molecular weight organic zwitterions SG11201602879UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361895338P 2013-10-24 2013-10-24
PCT/SG2014/000485 WO2015060784A1 (fr) 2013-10-24 2014-10-15 Procédés de récupération d'exosome à zwitterions organiques de poids moléculaire faible

Publications (1)

Publication Number Publication Date
SG11201602879UA true SG11201602879UA (en) 2016-05-30

Family

ID=52993252

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201602879UA SG11201602879UA (en) 2013-10-24 2014-10-15 Exosome recovery methods with low molecular weight organic zwitterions

Country Status (7)

Country Link
US (1) US9927427B2 (fr)
EP (1) EP3060911A4 (fr)
JP (1) JP6510508B2 (fr)
KR (1) KR20160075692A (fr)
CN (1) CN105849554B (fr)
SG (1) SG11201602879UA (fr)
WO (1) WO2015060784A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2344202B1 (fr) 2008-09-08 2020-03-11 Children's Medical Center Corporation Administration mucosale de molécules, protéines ou particules thérapeutiques couplées à des lipides céramides
WO2017117585A1 (fr) * 2015-12-30 2017-07-06 The Regents Of The University Of California Procédés permettant d'améliorer la production et l'isolement de vésicules d'origine cellulaire
WO2017175736A1 (fr) * 2016-04-04 2017-10-12 国立研究開発法人産業技術総合研究所 Procédé de préparation de vésicules membranaires convenant à l'analyse biophysique
KR101895916B1 (ko) * 2017-08-11 2018-09-07 주식회사 엑소코바이오 엑소좀 및/또는 세포외 소포체 및 이를 포함하는 조성물의 제조 방법
WO2019083201A2 (fr) * 2017-10-24 2019-05-02 주식회사 엑소코바이오 Utilisation d'une composition comprenant un exosome dérivé de cellules souches adipeuses en tant que principe actif pour améliorer la fonction rénale
CA3080521A1 (fr) 2017-10-27 2019-05-02 Children's Medical Center Corporation Lipides a base de ceramides a chaine courte et leurs utilisations
US11596876B2 (en) 2018-02-05 2023-03-07 Clemson University Research Foundation Channeled fibers in separation of biologically active nanoparticles
WO2019200293A1 (fr) * 2018-04-12 2019-10-17 Children's Medical Center Corporation Véhicules d'administration à base d'un lipide de type céramide et leurs utilisations
CN109609458A (zh) * 2018-12-29 2019-04-12 暨南大学 一种低速超滤离心结合聚合物沉淀技术分离外泌体的方法
TWI787697B (zh) * 2019-12-30 2022-12-21 財團法人工業技術研究院 外泌體的分離方法、膠體粒子及其製備方法
WO2021221368A1 (fr) * 2020-04-28 2021-11-04 주식회사 엠디뮨 Procédé de filtration de vésicule dérivée de cellules
CN111621471B (zh) * 2020-06-12 2022-03-11 成都世联康健生物科技有限公司 一种软组织胞外囊泡的提取方法及应用
CN114323863B (zh) * 2021-12-31 2023-12-22 吉林大学 一种外泌体阵列捕获探针的制备方法与应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6812023B1 (en) 2000-04-27 2004-11-02 Anosys, Inc. Methods of producing membrane vesicles
US20120244212A1 (en) * 2004-11-07 2012-09-27 Frederick Timothy Guilford Enhanced method and composition for the treatment of hiv+ tuberculosis patients with anti-retroviral drugs and liposomal encapsulation for delivery of reduced glutathione
US10545149B2 (en) 2008-10-06 2020-01-28 Morehouse School Of Medicine Detection of HIV-related proteins in urine
WO2011017137A2 (fr) * 2009-08-03 2011-02-10 Alnylam Pharmaceuticals, Inc. Procédés et compositions de traitement d'insectes
WO2011062244A1 (fr) * 2009-11-18 2011-05-26 Kuroda Masahiko Véhicule, son procédé de production, et ses applications
WO2012126531A1 (fr) * 2011-03-24 2012-09-27 Cavadis B.V. Méthode de diagnostic du syndrome coronaire aigu (sca)
KR101901830B1 (ko) * 2011-06-08 2018-09-27 에이전시 포 사이언스, 테크놀로지 앤드 리서치 제한된 공수화 크로마토그래피를 통한 생물학적 산물의 정제
CN102349998A (zh) * 2011-10-20 2012-02-15 天津大学 以外泌体为基础的疏水性抗癌药物制剂
US9777042B2 (en) * 2011-12-15 2017-10-03 Morehouse School Of Medicine Method of purifying HIV/SIV Nef from exosomal fusion proteins
KR101933621B1 (ko) 2012-09-28 2018-12-28 삼성전자주식회사 소포를 분리하기 위한 조성물, 키트 및 이를 이용하여 소포를 분리하는 방법
CN103197066B (zh) * 2013-03-07 2015-12-23 美国纳米材料创新有限公司 一种免疫脂质体生物芯片、其制备方法及其在生物检测中的应用

Also Published As

Publication number Publication date
EP3060911A1 (fr) 2016-08-31
JP2017505753A (ja) 2017-02-23
KR20160075692A (ko) 2016-06-29
WO2015060784A1 (fr) 2015-04-30
CN105849554A (zh) 2016-08-10
US9927427B2 (en) 2018-03-27
EP3060911A4 (fr) 2017-06-21
JP6510508B2 (ja) 2019-05-08
CN105849554B (zh) 2019-02-15
US20160266097A1 (en) 2016-09-15

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