SG11201602807PA - Use of semaphorin-4d binding molecules for treatment of atherosclerosis - Google Patents

Use of semaphorin-4d binding molecules for treatment of atherosclerosis

Info

Publication number
SG11201602807PA
SG11201602807PA SG11201602807PA SG11201602807PA SG11201602807PA SG 11201602807P A SG11201602807P A SG 11201602807PA SG 11201602807P A SG11201602807P A SG 11201602807PA SG 11201602807P A SG11201602807P A SG 11201602807PA SG 11201602807P A SG11201602807P A SG 11201602807PA
Authority
SG
Singapore
Prior art keywords
semaphorin
atherosclerosis
treatment
binding molecules
molecules
Prior art date
Application number
SG11201602807PA
Other languages
English (en)
Inventor
Maurice Zauderer
Original Assignee
Vaccinex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vaccinex Inc filed Critical Vaccinex Inc
Publication of SG11201602807PA publication Critical patent/SG11201602807PA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596Molecules with a "CD"-designation not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11201602807PA 2013-10-10 2014-10-10 Use of semaphorin-4d binding molecules for treatment of atherosclerosis SG11201602807PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361889421P 2013-10-10 2013-10-10
PCT/US2014/060129 WO2015054628A1 (en) 2013-10-10 2014-10-10 Use of semaphorin-4d binding molecules for treatment of atherosclerosis

Publications (1)

Publication Number Publication Date
SG11201602807PA true SG11201602807PA (en) 2016-05-30

Family

ID=52809873

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201602807PA SG11201602807PA (en) 2013-10-10 2014-10-10 Use of semaphorin-4d binding molecules for treatment of atherosclerosis

Country Status (18)

Country Link
US (1) US9512224B2 (es)
EP (1) EP3054976B1 (es)
JP (2) JP6760840B2 (es)
KR (1) KR102366682B1 (es)
CN (1) CN105848679A (es)
AU (1) AU2014331683B2 (es)
BR (1) BR112016008010A2 (es)
CA (1) CA2926944C (es)
DK (1) DK3054976T3 (es)
EA (1) EA037551B1 (es)
ES (1) ES2821814T3 (es)
IL (1) IL244976B (es)
MX (1) MX2016004551A (es)
NZ (1) NZ630881A (es)
PT (1) PT3054976T (es)
SG (1) SG11201602807PA (es)
WO (1) WO2015054628A1 (es)
ZA (1) ZA201602577B (es)

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NZ596136A (en) 2009-05-08 2013-12-20 Vaccinex Inc Anti-cd100 antibodies and methods for using the same
CA2851805C (en) 2011-10-11 2021-12-28 Vaccinex, Inc. Use of semaphorin-4d binding molecules for modulation of blood brain barrier permeability
US9708601B2 (en) 2012-04-26 2017-07-18 Vaccinex, Inc. Fusion proteins to facilitate selection of cells infected with specific immunoglobulin gene recombinant vaccinia virus
US10494440B2 (en) 2012-05-11 2019-12-03 Vaccinex, Inc. Use of semaphorin-4D binding molecules to promote neurogenesis following stroke
SG11201510505VA (en) 2013-06-25 2016-01-28 Vaccinex Inc Use of semaphorin-4d inhibitory molecules in combination with an immune modulating therapy to inhibit tumor growth and metastases
NZ630881A (en) 2013-10-10 2016-03-31 Vaccinex Inc Use of semaphorin-4d binding molecules for treatment of atherosclerosis
NZ630892A (en) 2013-10-21 2016-03-31 Vaccinex Inc Use of semaphorin-4d binding molecules for treating neurodegenerative disorders
JP7072521B2 (ja) 2016-04-22 2022-05-20 バクシネックス インコーポレーティッド ポックスウイルス細胞外エンベロープビリオン上での膜内在性タンパク質の提示
CN109563143A (zh) 2016-08-02 2019-04-02 瓦西尼斯公司 在牛痘病毒/真核细胞中产生多核苷酸文库的改良方法
CN106474559B (zh) * 2016-11-30 2019-07-12 西南交通大学 一种在心血管植入材料表面构建Sema 4D/Heparin微环境的方法
CN110325213A (zh) * 2017-02-22 2019-10-11 瓦西尼斯公司 神经退行性或神经炎性疾病中胶质细胞活化的早期检测
CN106983919B (zh) * 2017-03-06 2019-07-12 西南交通大学 一种Sema 4D-VEGF涂层的构建方法及应用
AU2018261947A1 (en) 2017-05-05 2019-11-07 Vaccinex, Inc. Human anti-semaphorin 4D antibody
CN108499220B (zh) * 2018-04-25 2020-07-31 山东纯江环境科技有限公司 石墨烯/聚丙烯非织造布过滤网制备方法及其应用
CN109125731B (zh) * 2018-10-22 2019-10-25 华中科技大学同济医学院附属协和医院 Sema4D/PlexinB1抑制剂在制备治疗及预防眼底血管疾病药物中的应用
AU2021297152A1 (en) 2020-06-25 2023-02-02 The Sydney Children's Hospitals Network Use of semaphorin-4D binding molecules for the treatment of Rett syndrome
CN116949097B (zh) * 2023-09-20 2023-12-12 江苏集萃药康生物科技股份有限公司 一种sema4d人源化小鼠模型的构建方法及其应用

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US10494440B2 (en) 2012-05-11 2019-12-03 Vaccinex, Inc. Use of semaphorin-4D binding molecules to promote neurogenesis following stroke
SG11201510505VA (en) 2013-06-25 2016-01-28 Vaccinex Inc Use of semaphorin-4d inhibitory molecules in combination with an immune modulating therapy to inhibit tumor growth and metastases
NZ630881A (en) 2013-10-10 2016-03-31 Vaccinex Inc Use of semaphorin-4d binding molecules for treatment of atherosclerosis
NZ630892A (en) 2013-10-21 2016-03-31 Vaccinex Inc Use of semaphorin-4d binding molecules for treating neurodegenerative disorders

Also Published As

Publication number Publication date
EP3054976A4 (en) 2017-05-17
IL244976A0 (en) 2016-05-31
MX2016004551A (es) 2016-07-22
EP3054976A1 (en) 2016-08-17
IL244976B (en) 2020-07-30
EA201690728A1 (ru) 2016-08-31
KR102366682B1 (ko) 2022-02-22
JP6760840B2 (ja) 2020-09-23
CN105848679A (zh) 2016-08-10
EA037551B1 (ru) 2021-04-13
KR20160062167A (ko) 2016-06-01
ES2821814T3 (es) 2021-04-27
WO2015054628A1 (en) 2015-04-16
US20150104462A1 (en) 2015-04-16
AU2014331683B2 (en) 2019-07-11
DK3054976T3 (da) 2020-09-28
ZA201602577B (en) 2020-11-25
JP2016539089A (ja) 2016-12-15
BR112016008010A2 (pt) 2017-09-26
CA2926944C (en) 2023-08-08
AU2014331683A1 (en) 2016-04-28
JP2019108359A (ja) 2019-07-04
NZ630881A (en) 2016-03-31
EP3054976B1 (en) 2020-07-08
PT3054976T (pt) 2020-08-05
US9512224B2 (en) 2016-12-06
CA2926944A1 (en) 2015-04-16

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