SG11201602138VA - A method for analysing a sample of immunoglobulin molecules - Google Patents

A method for analysing a sample of immunoglobulin molecules

Info

Publication number
SG11201602138VA
SG11201602138VA SG11201602138VA SG11201602138VA SG11201602138VA SG 11201602138V A SG11201602138V A SG 11201602138VA SG 11201602138V A SG11201602138V A SG 11201602138VA SG 11201602138V A SG11201602138V A SG 11201602138VA SG 11201602138V A SG11201602138V A SG 11201602138VA
Authority
SG
Singapore
Prior art keywords
analysing
sample
immunoglobulin molecules
immunoglobulin
molecules
Prior art date
Application number
SG11201602138VA
Other languages
English (en)
Inventor
Fredrik Olsson
Maria Nordgren
Malin Mejare
Sarah Fredriksson
Original Assignee
Genovis Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genovis Ab filed Critical Genovis Ab
Publication of SG11201602138VA publication Critical patent/SG11201602138VA/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G01N33/6857—Antibody fragments
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/53—Hinge
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/22—Cysteine endopeptidases (3.4.22)
    • C12Y304/2201—Streptopain (3.4.22.10)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96402—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals
    • G01N2333/96405—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals in general
    • G01N2333/96408—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals in general with EC number
    • G01N2333/96413—Cysteine endopeptidases (3.4.22)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00—Chemical aspects of mass spectrometric analysis of biological material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SG11201602138VA 2013-09-20 2014-09-18 A method for analysing a sample of immunoglobulin molecules SG11201602138VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1316744.0A GB201316744D0 (en) 2013-09-20 2013-09-20 Method
PCT/EP2014/069920 WO2015040125A1 (fr) 2013-09-20 2014-09-18 Procédé d'analyse d'un échantillon de molécules d'immunoglobulines

Publications (1)

Publication Number Publication Date
SG11201602138VA true SG11201602138VA (en) 2016-04-28

Family

ID=49553168

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201602138VA SG11201602138VA (en) 2013-09-20 2014-09-18 A method for analysing a sample of immunoglobulin molecules

Country Status (9)

Country Link
US (1) US20160231329A1 (fr)
EP (1) EP3047280A1 (fr)
JP (1) JP2016531546A (fr)
KR (1) KR20160079784A (fr)
AU (1) AU2014323081A1 (fr)
CA (1) CA2923704A1 (fr)
GB (1) GB201316744D0 (fr)
SG (1) SG11201602138VA (fr)
WO (1) WO2015040125A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002050107A2 (fr) * 2000-12-21 2002-06-27 Shire Biochem Inc. Antigenes de streptococcus pyogenes et fragments d'adn correspondants
CA2944767C (fr) 2014-04-04 2022-07-12 Mayo Foundation For Medical Education And Research Isotypage d'immunoglobulines par masse moleculaire precise
GB201502306D0 (en) 2015-02-12 2015-04-01 Hansa Medical Ab Protein
GB201502305D0 (en) 2015-02-12 2015-04-01 Hansa Medical Ab Protein
US11209439B2 (en) 2015-09-24 2021-12-28 Mayo Foundation For Medical Education And Research Identification of immunoglobulin free light chains by mass spectrometry
CN108291913B (zh) 2015-12-09 2021-08-17 豪夫迈·罗氏有限公司 确定体内相互作用模式的方法
US12006530B2 (en) 2016-02-04 2024-06-11 Genovis Ab Streptococcal proteases
EP3465221B1 (fr) * 2016-05-27 2020-07-22 H. Hoffnabb-La Roche Ag Procédé bioanalytique pour la caractérisation de conjugués anticorps-médicament spécifiques d'un site
US10955420B2 (en) 2016-09-07 2021-03-23 Mayo Foundation For Medical Education And Research Identification and monitoring of cleaved immunoglobulins by molecular mass
WO2018093868A1 (fr) * 2016-11-16 2018-05-24 University Of Florida Research Foundation, Inc. Protéases d'immunoglobulines, compositions et leurs utilisations
US11584922B2 (en) 2017-05-26 2023-02-21 Genovis Ab Protease and binding polypeptide for O-glycoproteins
WO2019055634A1 (fr) 2017-09-13 2019-03-21 Mayo Foundation For Medical Education And Research Identification et surveillance d'un inhibiteur d'apoptose de macrophage

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965709A (en) * 1991-08-14 1999-10-12 Genentech, Inc. IgE antagonists
GB0130228D0 (en) * 2001-12-18 2002-02-06 Hansa Medica Ab Protein
EP2748197A2 (fr) * 2011-08-26 2014-07-02 Merrimack Pharmaceuticals, Inc. Anticorps bispécifiques à fc en tandem

Also Published As

Publication number Publication date
JP2016531546A (ja) 2016-10-13
WO2015040125A1 (fr) 2015-03-26
GB201316744D0 (en) 2013-11-06
US20160231329A1 (en) 2016-08-11
AU2014323081A1 (en) 2016-03-31
KR20160079784A (ko) 2016-07-06
CA2923704A1 (fr) 2015-03-26
EP3047280A1 (fr) 2016-07-27

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