SG11201509742QA - Combinations of an anti-pd-l1 antibody and a mek inhibitor and/or a braf inhibitor - Google Patents
Combinations of an anti-pd-l1 antibody and a mek inhibitor and/or a braf inhibitorInfo
- Publication number
- SG11201509742QA SG11201509742QA SG11201509742QA SG11201509742QA SG11201509742QA SG 11201509742Q A SG11201509742Q A SG 11201509742QA SG 11201509742Q A SG11201509742Q A SG 11201509742QA SG 11201509742Q A SG11201509742Q A SG 11201509742QA SG 11201509742Q A SG11201509742Q A SG 11201509742QA
- Authority
- SG
- Singapore
- Prior art keywords
- inhibitor
- antibody
- combinations
- braf
- mek
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361830220P | 2013-06-03 | 2013-06-03 | |
| PCT/IB2014/061895 WO2014195852A1 (fr) | 2013-06-03 | 2014-06-02 | Combinaisons d'un anticorps anti-pd-l1 et d'un inhibiteur de mek et/ou d'un inhibiteur de braf |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201509742QA true SG11201509742QA (en) | 2015-12-30 |
Family
ID=50943361
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201509742QA SG11201509742QA (en) | 2013-06-03 | 2014-06-02 | Combinations of an anti-pd-l1 antibody and a mek inhibitor and/or a braf inhibitor |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20160089434A1 (fr) |
| EP (1) | EP3003282A1 (fr) |
| JP (1) | JP2016520643A (fr) |
| KR (1) | KR20160013049A (fr) |
| CN (1) | CN105658206A (fr) |
| AU (3) | AU2014276440A1 (fr) |
| BR (1) | BR112015028326A8 (fr) |
| CA (1) | CA2909052A1 (fr) |
| CL (1) | CL2015003522A1 (fr) |
| HK (1) | HK1216231A1 (fr) |
| MA (1) | MA38643A1 (fr) |
| MX (1) | MX2015016592A (fr) |
| PH (1) | PH12015502415A1 (fr) |
| RU (1) | RU2015154275A (fr) |
| SG (1) | SG11201509742QA (fr) |
| TN (1) | TN2015000444A1 (fr) |
| WO (1) | WO2014195852A1 (fr) |
Families Citing this family (74)
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| US20140031250A1 (en) | 2010-10-07 | 2014-01-30 | David Tsai Ting | Biomarkers of Cancer |
| MY193562A (en) | 2011-08-01 | 2022-10-19 | Genentech Inc | Methods of treating cancer using pd-1 axis binding antagonists and mek inhibitors |
| WO2015048312A1 (fr) | 2013-09-26 | 2015-04-02 | Costim Pharmaceuticals Inc. | Méthodes de traitement de cancers hématologiques |
| MY175472A (en) | 2013-09-27 | 2020-06-29 | Genentech Inc | Anti-pdl1 antibody formulations |
| CR20160319A (es) | 2013-12-12 | 2016-11-08 | Jiangsu Hengrui Medicine Co | Anticuerpo pd-1, fragmento de union al antigeno de este y uso médico de este |
| KR20240017102A (ko) * | 2013-12-17 | 2024-02-06 | 제넨테크, 인크. | Pd-1 축 결합 길항제 및 탁산을 이용한 암 치료 방법 |
| JOP20200094A1 (ar) | 2014-01-24 | 2017-06-16 | Dana Farber Cancer Inst Inc | جزيئات جسم مضاد لـ pd-1 واستخداماتها |
| JOP20200096A1 (ar) | 2014-01-31 | 2017-06-16 | Children’S Medical Center Corp | جزيئات جسم مضاد لـ tim-3 واستخداماتها |
| PL3169361T3 (pl) | 2014-07-15 | 2019-11-29 | Hoffmann La Roche | Kompozycje do leczenia nowotworu z użyciem związków antagonistycznych wiązania osi pd-1 i inhibitorów mek |
| EP3191126B1 (fr) | 2014-09-13 | 2020-05-13 | Novartis AG | Thérapies combinées d'inhibiteurs d'alk |
| CU20170052A7 (es) | 2014-10-14 | 2017-11-07 | Dana Farber Cancer Inst Inc | Moléculas de anticuerpo que se unen a pd-l1 |
| BR112017016902A2 (pt) * | 2015-02-12 | 2018-03-27 | Beyondspring Pharmaceuticals, Inc. | composição farmacêutica, respectivo uso e método para tratar câncer |
| KR102626155B1 (ko) | 2015-03-06 | 2024-01-17 | 비욘드스프링 파마수티컬스, 인코포레이티드. | Ras 돌연변이와 관련된 암의 치료 방법 |
| EP3067062A1 (fr) * | 2015-03-13 | 2016-09-14 | Ipsen Pharma S.A.S. | Combinaison de tasquinimod ou d'un sel pharmaceutiquement acceptable de celui-ci et d'un inhibiteur de pd1 et/ou de pdl1, destinée à être utilisée comme médicament |
| CA2978942A1 (fr) | 2015-03-13 | 2016-09-22 | Cytomx Therapeutics, Inc. | Anticorps anti-pdl1, anticorps anti-pld1 activables, et leurs procedes d'utilisation |
| KR20160120157A (ko) * | 2015-04-07 | 2016-10-17 | 주식회사 메드팩토 | 암 예방 또는 치료용 약학적 조성물 및 이를 이용한 방법 |
| KR20180018538A (ko) | 2015-06-17 | 2018-02-21 | 제넨테크, 인크. | Pd-1 축 결합 길항제 및 탁산을 사용하여 국소적 진행성 또는 전이성 유방암을 치료하는 방법 |
| KR20180027563A (ko) | 2015-07-13 | 2018-03-14 | 비욘드스프링 파마수티컬스, 인코포레이티드. | 플리나불린 조성물 |
| ES2839212T3 (es) | 2015-09-29 | 2021-07-05 | Inst Nat Sante Rech Med | Métodos para determinar el estado metabólico de linfomas B |
| JP6983371B2 (ja) | 2015-11-17 | 2021-12-17 | スーヂョウ サンケイディア バイオファーマスーティカルズ カンパニー リミテッド | 抗ｐｄ−ｌ１抗体、その抗原結合フラグメントおよびその医療用途 |
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| US20110280877A1 (en) | 2010-05-11 | 2011-11-17 | Koji Tamada | Inhibition of B7-H1/CD80 interaction and uses thereof |
| MY193562A (en) * | 2011-08-01 | 2022-10-19 | Genentech Inc | Methods of treating cancer using pd-1 axis binding antagonists and mek inhibitors |
| LT2785375T (lt) | 2011-11-28 | 2020-11-10 | Merck Patent Gmbh | Anti-pd-l1 antikūnai ir jų panaudojimas |
| US9856320B2 (en) | 2012-05-15 | 2018-01-02 | Bristol-Myers Squibb Company | Cancer immunotherapy by disrupting PD-1/PD-L1 signaling |
-
2014
- 2014-06-02 EP EP14730595.7A patent/EP3003282A1/fr not_active Withdrawn
- 2014-06-02 MA MA38643A patent/MA38643A1/fr unknown
- 2014-06-02 JP JP2016517711A patent/JP2016520643A/ja active Pending
- 2014-06-02 AU AU2014276440A patent/AU2014276440A1/en not_active Abandoned
- 2014-06-02 US US14/891,984 patent/US20160089434A1/en not_active Abandoned
- 2014-06-02 MX MX2015016592A patent/MX2015016592A/es unknown
- 2014-06-02 CA CA2909052A patent/CA2909052A1/fr not_active Abandoned
- 2014-06-02 BR BR112015028326A patent/BR112015028326A8/pt not_active IP Right Cessation
- 2014-06-02 WO PCT/IB2014/061895 patent/WO2014195852A1/fr active Application Filing
- 2014-06-02 RU RU2015154275A patent/RU2015154275A/ru not_active Application Discontinuation
- 2014-06-02 CN CN201480031803.1A patent/CN105658206A/zh active Pending
- 2014-06-02 TN TN2015000444A patent/TN2015000444A1/en unknown
- 2014-06-02 SG SG11201509742QA patent/SG11201509742QA/en unknown
- 2014-06-02 KR KR1020157034092A patent/KR20160013049A/ko not_active Application Discontinuation
-
2015
- 2015-10-20 PH PH12015502415A patent/PH12015502415A1/en unknown
- 2015-12-02 CL CL2015003522A patent/CL2015003522A1/es unknown
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2016
- 2016-04-13 HK HK16104210.8A patent/HK1216231A1/zh unknown
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2017
- 2017-05-02 AU AU2017202926A patent/AU2017202926A1/en not_active Abandoned
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2019
- 2019-02-27 AU AU2019201366A patent/AU2019201366A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2016520643A (ja) | 2016-07-14 |
| AU2019201366A1 (en) | 2019-03-21 |
| EP3003282A1 (fr) | 2016-04-13 |
| CA2909052A1 (fr) | 2014-12-11 |
| KR20160013049A (ko) | 2016-02-03 |
| BR112015028326A2 (pt) | 2017-07-25 |
| US20160089434A1 (en) | 2016-03-31 |
| HK1216231A1 (zh) | 2016-10-28 |
| RU2015154275A3 (fr) | 2018-05-11 |
| MX2015016592A (es) | 2016-03-16 |
| BR112015028326A8 (pt) | 2018-01-23 |
| MA38643A1 (fr) | 2017-10-31 |
| PH12015502415A1 (en) | 2016-02-22 |
| CL2015003522A1 (es) | 2016-09-16 |
| RU2015154275A (ru) | 2017-07-17 |
| CN105658206A (zh) | 2016-06-08 |
| WO2014195852A1 (fr) | 2014-12-11 |
| TN2015000444A1 (en) | 2017-04-06 |
| AU2014276440A1 (en) | 2015-11-05 |
| AU2017202926A1 (en) | 2017-05-25 |
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