SG11201508544VA - Genetic marker for early breast cancer prognosis prediction and diagnosis, and use thereof - Google Patents

Genetic marker for early breast cancer prognosis prediction and diagnosis, and use thereof

Info

Publication number
SG11201508544VA
SG11201508544VA SG11201508544VA SG11201508544VA SG11201508544VA SG 11201508544V A SG11201508544V A SG 11201508544VA SG 11201508544V A SG11201508544V A SG 11201508544VA SG 11201508544V A SG11201508544V A SG 11201508544VA SG 11201508544V A SG11201508544V A SG 11201508544VA
Authority
SG
Singapore
Prior art keywords
diagnosis
breast cancer
genetic marker
cancer prognosis
prognosis prediction
Prior art date
Application number
SG11201508544VA
Inventor
Young Kee Shin
Young-Deug Kim
Eu Sel Oh
Jun Young Choi
Sang Rea Cho
Original Assignee
Gencurix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gencurix Inc filed Critical Gencurix Inc
Publication of SG11201508544VA publication Critical patent/SG11201508544VA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57415—Specifically defined cancers of breast
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
SG11201508544VA 2013-04-18 2014-04-18 Genetic marker for early breast cancer prognosis prediction and diagnosis, and use thereof SG11201508544VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020130043160A KR101672531B1 (en) 2013-04-18 2013-04-18 Genetic markers for prognosing or predicting early stage breast cancer and uses thereof
PCT/KR2014/003384 WO2014171778A1 (en) 2013-04-18 2014-04-18 Genetic marker for early breast cancer prognosis prediction and diagnosis, and use thereof

Publications (1)

Publication Number Publication Date
SG11201508544VA true SG11201508544VA (en) 2015-11-27

Family

ID=51731629

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201508544VA SG11201508544VA (en) 2013-04-18 2014-04-18 Genetic marker for early breast cancer prognosis prediction and diagnosis, and use thereof

Country Status (7)

Country Link
US (1) US20160102359A1 (en)
EP (1) EP2988131A4 (en)
JP (1) JP2016516426A (en)
KR (1) KR101672531B1 (en)
CN (1) CN105339797B (en)
SG (1) SG11201508544VA (en)
WO (1) WO2014171778A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3155592B1 (en) * 2014-06-10 2019-09-11 Leland Stanford Junior University Predicting breast cancer recurrence directly from image features computed from digitized immunohistopathology tissue slides
KR101896558B1 (en) * 2016-11-21 2018-09-07 주식회사 젠큐릭스 Methods for predicting risk of recurrence of breast cancer patients
KR101950717B1 (en) * 2016-11-23 2019-02-21 주식회사 젠큐릭스 Methods for predicting effectiveness of chemotherapy for breast cancer patients
KR101896545B1 (en) * 2016-11-25 2018-09-07 주식회사 젠큐릭스 Methods for predicting risk of recurrence of breast cancer patients
CN107164519A (en) * 2017-06-26 2017-09-15 深圳优圣康医学检验所有限公司 A kind of primer and probe that ESR1 gene mutations are detected based on fluorescent PCR
CA3068437A1 (en) * 2017-06-27 2019-01-03 Institute For Cancer Research D/B/A The Research Institute Of Fox Chascancer Center Mhc-i genotype restricts the oncogenic mutational landscape
KR20190071393A (en) 2017-12-14 2019-06-24 충남대학교산학협력단 A composition comprising metallothionein 2A for predicting metastasis and prognosis of breast cancer patients
CN108441559B (en) * 2018-02-27 2021-01-05 海门善准生物科技有限公司 Application of immune-related gene group as marker in preparation of product for evaluating distant metastasis risk of high-proliferative breast cancer
CN109801680B (en) * 2018-12-03 2023-02-28 广州中医药大学(广州中医药研究院) Tumor metastasis and recurrence prediction method and system based on TCGA database
CN110373463A (en) * 2019-07-08 2019-10-25 江苏医药职业学院 Detect application and the kit of the reagent of cross-film P24 transport protein 9 expression
CN116144670A (en) * 2022-05-20 2023-05-23 中国医学科学院肿瘤医院 Application of LOC107984813 in diagnosis and treatment of cancers

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050100933A1 (en) * 2003-06-18 2005-05-12 Arcturus Bioscience, Inc. Breast cancer survival and recurrence
GB0323225D0 (en) * 2003-10-03 2003-11-05 Ncc Technology Ventures Pte Lt Materials and methods relating to breast cancer classification
US20100035240A1 (en) 2004-08-10 2010-02-11 Cardiff Biologicals Limited Methods and kit for the prognosis of breast cancer
US8065093B2 (en) * 2004-10-06 2011-11-22 Agency For Science, Technology, And Research Methods, systems, and compositions for classification, prognosis, and diagnosis of cancers
US20070059720A9 (en) * 2004-12-06 2007-03-15 Suzanne Fuqua RNA expression profile predicting response to tamoxifen in breast cancer patients
WO2006074367A2 (en) * 2005-01-05 2006-07-13 Sloan-Kettering Institute For Cancer Research Method of predicting and reducing risk of metastasis of breast cancer to lung
EP1777523A1 (en) * 2005-10-19 2007-04-25 INSERM (Institut National de la Santé et de la Recherche Médicale) An in vitro method for the prognosis of progression of a cancer and of the outcome in a patient and means for performing said method
FR2892730A1 (en) * 2005-10-28 2007-05-04 Biomerieux Sa Detecting the presence/risk of cancer development in a mammal, comprises detecting the presence/absence or (relative) quantity e.g. of nucleic acids and/or polypeptides coded by the nucleic acids, which indicates the presence/risk
CN101573453A (en) * 2006-09-05 2009-11-04 维里德克斯有限责任公司 Methods of predicting distant metastasis of lymph node-negative primary breast cancer using biological pathway gene expression analysis
PT2121977T (en) * 2007-01-11 2017-08-18 Erasmus Univ Medical Center Circular chromosome conformation capture (4c)
EP2520668B1 (en) 2007-01-31 2014-12-24 Celera Corporation A molecular prognostic signature for predicting breast cancer distant metastasis, and uses thereof
BRPI0817031A2 (en) * 2007-09-07 2017-05-23 Univ Bruxelles Diagnostic kit and method for cancer prognosis in mammalian subjects
US20090123932A1 (en) * 2007-11-09 2009-05-14 Anne-Marie Mes-Masson Quantitative test to detect disease progression markers of epithelial ovarian cancer patients
KR20090088757A (en) * 2008-02-15 2009-08-20 재단법인서울대학교산학협력재단 Data processing, analysis method of gene expression data to identify endogenous reference genes
EP2268838A1 (en) * 2008-04-11 2011-01-05 China Synthetic Rubber Corporation Methods, agents and kits for the detection of cancer
DK2504451T3 (en) * 2009-11-23 2019-08-05 Genomic Health Inc Methods for predicting the clinical course of cancer
KR101421326B1 (en) * 2010-03-30 2014-07-21 서울대학교산학협력단 Composition for predicting prognosis of breast cancer and kit comprising the same
KR101287600B1 (en) 2011-01-04 2013-07-18 주식회사 젠큐릭스 Prognostic Genes for Early Breast Cancer and Prognostic Model for Early Breast Cancer Patients
WO2012166700A2 (en) * 2011-05-29 2012-12-06 Lisanti Michael P Molecular profiling of a lethal tumor microenvironment

Also Published As

Publication number Publication date
EP2988131A1 (en) 2016-02-24
WO2014171778A1 (en) 2014-10-23
WO2014171778A8 (en) 2015-12-23
CN105339797B (en) 2017-07-11
CN105339797A (en) 2016-02-17
EP2988131A4 (en) 2017-04-12
KR20140125239A (en) 2014-10-28
US20160102359A1 (en) 2016-04-14
KR101672531B1 (en) 2016-11-17
JP2016516426A (en) 2016-06-09

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