EP3322823A4 - Methods for diagnosis, prognosis and monitoring of breast cancer and reagents therefor - Google Patents
Methods for diagnosis, prognosis and monitoring of breast cancer and reagents therefor Download PDFInfo
- Publication number
- EP3322823A4 EP3322823A4 EP16823558.8A EP16823558A EP3322823A4 EP 3322823 A4 EP3322823 A4 EP 3322823A4 EP 16823558 A EP16823558 A EP 16823558A EP 3322823 A4 EP3322823 A4 EP 3322823A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- prognosis
- diagnosis
- monitoring
- methods
- breast cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562192540P | 2015-07-14 | 2015-07-14 | |
| PCT/AU2016/050615 WO2017008117A1 (en) | 2015-07-14 | 2016-07-14 | Methods for diagnosis, prognosis and monitoring of breast cancer and reagents therefor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP3322823A1 EP3322823A1 (en) | 2018-05-23 |
| EP3322823A4 true EP3322823A4 (en) | 2019-06-19 |
Family
ID=57756617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP16823558.8A Withdrawn EP3322823A4 (en) | 2015-07-14 | 2016-07-14 | Methods for diagnosis, prognosis and monitoring of breast cancer and reagents therefor |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP3322823A4 (en) |
| CN (1) | CN107922977A (en) |
| AU (1) | AU2016293381A1 (en) |
| WO (1) | WO2017008117A1 (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108676879A (en) * | 2018-05-24 | 2018-10-19 | 中国科学院北京基因组研究所 | Special application of the methylation sites as breast cancer molecular classification diagnosis marker |
| WO2020252721A1 (en) * | 2019-06-20 | 2020-12-24 | The Johns Hopkins University | Dna methylation markers and their use in differentiation of suspected cancerous lymph node biopsy samples |
| WO2021174262A1 (en) * | 2020-02-28 | 2021-09-02 | Loma Linda University | Methods of evaluating breast cancer prognosis and treatment regimens based on methylation status of the ins-igf2 region |
| CN111349695A (en) * | 2020-03-30 | 2020-06-30 | 陕西科技大学 | GATA3 gene methylation detection kit based on pyrosequencing technology and detection method |
| CN111235241A (en) * | 2020-03-30 | 2020-06-05 | 陕西科技大学 | FOXA1 gene methylation detection kit based on pyrosequencing technology and detection method |
| WO2022000399A1 (en) * | 2020-07-02 | 2022-01-06 | The Johns Hopkins University | Methylated markers for accurate detection of primary central nervous system and systemic diffuse large b cell lymphoma |
| WO2022123419A1 (en) * | 2020-12-08 | 2022-06-16 | Pfizer Inc. | Treatment of luminal subtypes of hr-positive, her2-negative early breast cancer with palbociclib |
| CN114480652A (en) * | 2022-02-21 | 2022-05-13 | 深圳市陆为生物技术有限公司 | Product for evaluating responsiveness of breast cancer patient to adjuvant endocrine therapy |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003000189A2 (en) * | 2001-06-21 | 2003-01-03 | Baylor College Of Medicine | Prediction, diagnosis and treatment of endocrine resistant breast cancer, using p38 mapk pathway |
| WO2006004597A2 (en) * | 2004-06-01 | 2006-01-12 | University Of Southern California | Association of breast cancer dna methylation profiles with hormone receptor status and response to tamoxifen |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130296328A1 (en) * | 2011-01-20 | 2013-11-07 | Université Libre de Bruxelles | Epigenetic portraits of human breast cancers |
-
2016
- 2016-07-14 CN CN201680051447.9A patent/CN107922977A/en active Pending
- 2016-07-14 AU AU2016293381A patent/AU2016293381A1/en not_active Abandoned
- 2016-07-14 WO PCT/AU2016/050615 patent/WO2017008117A1/en active Application Filing
- 2016-07-14 EP EP16823558.8A patent/EP3322823A4/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003000189A2 (en) * | 2001-06-21 | 2003-01-03 | Baylor College Of Medicine | Prediction, diagnosis and treatment of endocrine resistant breast cancer, using p38 mapk pathway |
| WO2006004597A2 (en) * | 2004-06-01 | 2006-01-12 | University Of Southern California | Association of breast cancer dna methylation profiles with hormone receptor status and response to tamoxifen |
Non-Patent Citations (6)
| Title |
|---|
| CAROLYN L SMITH ET AL: "Elevated nuclear expression of the SMRT corepressor in breast cancer is associated with earlier tumor recurrence", BREAST CANCER RESEARCH AND TREATMENT, KLUWER ACADEMIC PUBLISHERS, BO, vol. 136, no. 1, 27 September 2012 (2012-09-27), pages 253 - 265, XP035125727, ISSN: 1573-7217, DOI: 10.1007/S10549-012-2262-7 * |
| K W MERRELL ET AL: "Differential recruitment of nuclear receptor coregulators in ligand-dependent transcriptional repression by estrogen receptor-[alpha]", ONCOGENE, vol. 30, no. 13, 22 November 2010 (2010-11-22), London, pages 1608 - 1614, XP055587477, ISSN: 0950-9232, DOI: 10.1038/onc.2010.528 * |
| L. ZHANG ET AL: "SpliceArray Profiling of Breast Cancer Reveals a Novel Variant of NCOR2/SMRT That Is Associated with Tamoxifen Resistance and Control of ER? Transcriptional Activity", CANCER RESEARCH, vol. 73, no. 1, 1 November 2012 (2012-11-01), Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA, pages 246 - 255, XP055367636, ISSN: 0008-5472, DOI: 10.1158/0008-5472.CAN-12-2241 * |
| RYO AKIHIDE ET AL: "Pinning down HER2-ER crosstalk in SMRT regulation.", TRENDS IN BIOCHEMICAL SCIENCES APR 2009, vol. 34, no. 4, April 2009 (2009-04-01), pages 162 - 165, XP002791216, ISSN: 0968-0004 * |
| See also references of WO2017008117A1 * |
| T VAN AGTHOVEN ET AL: "CITED2 and NCOR2 in anti-oestrogen resistance and progression of breast cancer", BRITISH JOURNAL OF CANCER, vol. 101, no. 11, 10 November 2009 (2009-11-10), GB, pages 1824 - 1832, XP055587459, ISSN: 0007-0920, DOI: 10.1038/sj.bjc.6605423 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN107922977A (en) | 2018-04-17 |
| EP3322823A1 (en) | 2018-05-23 |
| WO2017008117A1 (en) | 2017-01-19 |
| AU2016293381A1 (en) | 2018-01-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 20180205 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
| AX | Request for extension of the european patent |
Extension state: BA ME |
|
| DAV | Request for validation of the european patent (deleted) | ||
| DAX | Request for extension of the european patent (deleted) | ||
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20190522 |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12Q 1/48 20060101ALI20190514BHEP Ipc: C12Q 1/68 20180101AFI20190514BHEP Ipc: G01N 33/574 20060101ALI20190514BHEP |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 20191218 |