SG11201504974PA - Self-assembling ultrashort peptides modified with bioactive agents by click chemistry - Google Patents

Self-assembling ultrashort peptides modified with bioactive agents by click chemistry

Info

Publication number
SG11201504974PA
SG11201504974PA SG11201504974PA SG11201504974PA SG11201504974PA SG 11201504974P A SG11201504974P A SG 11201504974PA SG 11201504974P A SG11201504974P A SG 11201504974PA SG 11201504974P A SG11201504974P A SG 11201504974PA SG 11201504974P A SG11201504974P A SG 11201504974PA
Authority
SG
Singapore
Prior art keywords
assembling
self
bioactive agents
click chemistry
peptides modified
Prior art date
Application number
SG11201504974PA
Other languages
English (en)
Inventor
Michael R Reithofer
Charlotte A E Hauser
Kiat Hwa Chan
Archana Mishra
Original Assignee
Agency Science Tech & Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency Science Tech & Res filed Critical Agency Science Tech & Res
Priority to SG11201504974PA priority Critical patent/SG11201504974PA/en
Publication of SG11201504974PA publication Critical patent/SG11201504974PA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/282Platinum compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
SG11201504974PA 2012-12-24 2013-12-24 Self-assembling ultrashort peptides modified with bioactive agents by click chemistry SG11201504974PA (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SG11201504974PA SG11201504974PA (en) 2012-12-24 2013-12-24 Self-assembling ultrashort peptides modified with bioactive agents by click chemistry

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SG2012095279 2012-12-24
SG11201504974PA SG11201504974PA (en) 2012-12-24 2013-12-24 Self-assembling ultrashort peptides modified with bioactive agents by click chemistry
PCT/SG2013/000549 WO2014104974A2 (fr) 2012-12-24 2013-12-24 Peptides ultra-courts à auto-assemblage modifiés par des agents bioactifs par chimie clic

Publications (1)

Publication Number Publication Date
SG11201504974PA true SG11201504974PA (en) 2015-07-30

Family

ID=54063249

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201504974PA SG11201504974PA (en) 2012-12-24 2013-12-24 Self-assembling ultrashort peptides modified with bioactive agents by click chemistry

Country Status (3)

Country Link
US (1) US10117946B2 (fr)
SG (1) SG11201504974PA (fr)
WO (1) WO2014104974A2 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201504974PA (en) 2012-12-24 2015-07-30 Agency Science Tech & Res Self-assembling ultrashort peptides modified with bioactive agents by click chemistry
MX2016006988A (es) * 2013-11-30 2017-02-17 Agency Science Tech & Res Nuevos peptidos hidrofobos ultracortos que se autoensamblan en hidrogeles nanofibrosos y sus usos.
JP2017501136A (ja) 2013-11-30 2017-01-12 エージェンシー フォー サイエンス,テクノロジー アンド リサーチ バイオファブリケーション及びプリンティングのための構成要素としての自己組織化ペプチド、ペプチド模倣体及びペプチド結合体
WO2019090350A2 (fr) * 2017-11-06 2019-05-09 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Matériaux peptidiques adhésifs humides et leur utilisation
EP3845544B1 (fr) 2018-09-01 2023-11-15 Beijing Showby Pharmaceutical Co., Ltd. Phosphate de composé de platine et son procédé de préparation
CN112300246B (zh) * 2019-07-30 2023-01-13 首都医科大学 天冬酰茶氨酸rgds修饰的5-氟尿嘧啶,其合成,活性和应用
CN110898250B (zh) * 2019-11-28 2020-11-13 浙江大学 一种用于皮肤移植的自降解水凝胶粘合剂材料及其制备方法
CN111420119A (zh) * 2020-04-16 2020-07-17 南通大学 促进神经再生的活性多肽在材料表面共价接枝的方法及其应用
CN113350572B (zh) * 2020-12-03 2023-07-14 深圳市第二人民医院(深圳市转化医学研究院) 一种医用温敏型水凝胶及其制备方法和应用
CN113754730B (zh) * 2021-09-17 2022-11-08 中国药科大学 可以自组装形成ph响应载药水凝胶的多肽、水凝胶及其制备方法和用途
CN113969272B (zh) * 2021-11-30 2023-09-01 苏州携创生物技术有限公司 一种突变型蛋白酶3和生物素的偶联物及其制备方法及应用
CN115806736B (zh) * 2022-12-29 2024-03-26 中国科学院长春应用化学研究所 一种mmp酶响应的可注射聚氨基酸水凝胶及其制备方法和应用
CN118252943B (zh) * 2023-10-25 2024-09-20 常州市智态生创科技有限公司 一种短肽偶联药物及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7179784B2 (en) * 2001-07-10 2007-02-20 Massachusetts Institute Of Technology Surfactant peptide nanostructures, and uses thereof
JP2010526091A (ja) 2007-04-30 2010-07-29 インテザイン テクノロジーズ, インコーポレイテッド 癌の処置のための生物学的な標的基の改変
WO2010108122A1 (fr) * 2009-03-20 2010-09-23 Sanford-Burnham Medical Research Institute Administration ciblee d'agents chimiotherapeutiques
SG184345A1 (en) * 2010-03-31 2012-11-29 Agency Science Tech & Res Amphiphilic linear peptide/peptoid and hydrogel comprising the same
SG11201504974PA (en) 2012-12-24 2015-07-30 Agency Science Tech & Res Self-assembling ultrashort peptides modified with bioactive agents by click chemistry

Also Published As

Publication number Publication date
WO2014104974A3 (fr) 2016-07-07
US20150352220A1 (en) 2015-12-10
WO2014104974A2 (fr) 2014-07-03
US10117946B2 (en) 2018-11-06

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