SG11201504974PA - Self-assembling ultrashort peptides modified with bioactive agents by click chemistry - Google Patents

Self-assembling ultrashort peptides modified with bioactive agents by click chemistry

Info

Publication number
SG11201504974PA
SG11201504974PA SG11201504974PA SG11201504974PA SG11201504974PA SG 11201504974P A SG11201504974P A SG 11201504974PA SG 11201504974P A SG11201504974P A SG 11201504974PA SG 11201504974P A SG11201504974P A SG 11201504974PA SG 11201504974P A SG11201504974P A SG 11201504974PA
Authority
SG
Singapore
Prior art keywords
assembling
self
bioactive agents
click chemistry
peptides modified
Prior art date
Application number
SG11201504974PA
Inventor
Michael R Reithofer
Charlotte A E Hauser
Kiat Hwa Chan
Archana Mishra
Original Assignee
Agency Science Tech & Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency Science Tech & Res filed Critical Agency Science Tech & Res
Priority to SG11201504974PA priority Critical patent/SG11201504974PA/en
Publication of SG11201504974PA publication Critical patent/SG11201504974PA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/282—Platinum compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
SG11201504974PA 2012-12-24 2013-12-24 Self-assembling ultrashort peptides modified with bioactive agents by click chemistry SG11201504974PA (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SG11201504974PA SG11201504974PA (en) 2012-12-24 2013-12-24 Self-assembling ultrashort peptides modified with bioactive agents by click chemistry

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SG2012095279 2012-12-24
SG11201504974PA SG11201504974PA (en) 2012-12-24 2013-12-24 Self-assembling ultrashort peptides modified with bioactive agents by click chemistry
PCT/SG2013/000549 WO2014104974A2 (en) 2012-12-24 2013-12-24 Self-assembling ultrashort peptides modified with bioactive agents by click chemistry

Publications (1)

Publication Number Publication Date
SG11201504974PA true SG11201504974PA (en) 2015-07-30

Family

ID=54063249

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201504974PA SG11201504974PA (en) 2012-12-24 2013-12-24 Self-assembling ultrashort peptides modified with bioactive agents by click chemistry

Country Status (3)

Country Link
US (1) US10117946B2 (en)
SG (1) SG11201504974PA (en)
WO (1) WO2014104974A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201504974PA (en) 2012-12-24 2015-07-30 Agency Science Tech & Res Self-assembling ultrashort peptides modified with bioactive agents by click chemistry
MX2016006988A (en) * 2013-11-30 2017-02-17 Agency Science Tech & Res Novel ultrashort hydrophobic peptides that self-assemble into nanofibrous hydrogels and their uses.
JP2017501136A (en) 2013-11-30 2017-01-12 エージェンシー フォー サイエンス，テクノロジー アンド リサーチ Self-assembling peptides, peptidomimetics and peptide conjugates as building blocks for biofabrication and printing
WO2019090350A2 (en) * 2017-11-06 2019-05-09 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Wet adhesive peptide materials and their use
EP3845544B1 (en) 2018-09-01 2023-11-15 Beijing Showby Pharmaceutical Co., Ltd. Phosphate of platinum compound and preparation method therefor
CN112300246B (en) * 2019-07-30 2023-01-13 首都医科大学 5-fluorouracil modified by aspartyl theanine RGDS, and synthesis, activity and application thereof
CN110898250B (en) * 2019-11-28 2020-11-13 浙江大学 Self-degradable hydrogel adhesive material for skin transplantation and preparation method thereof
CN111420119A (en) * 2020-04-16 2020-07-17 南通大学 Method for covalently grafting active polypeptide for promoting nerve regeneration on material surface and application thereof
CN113350572B (en) * 2020-12-03 2023-07-14 深圳市第二人民医院(深圳市转化医学研究院) Medical temperature-sensitive hydrogel and preparation method and application thereof
CN113754730B (en) * 2021-09-17 2022-11-08 中国药科大学 Polypeptide capable of self-assembling to form PH-responsive drug-loaded hydrogel, preparation method and application thereof
CN113969272B (en) * 2021-11-30 2023-09-01 苏州携创生物技术有限公司 Conjugate of mutant protease 3 and biotin and preparation method and application thereof
CN115806736B (en) * 2022-12-29 2024-03-26 中国科学院长春应用化学研究所 MMP enzyme-responsive injectable polyamino acid hydrogel and preparation method and application thereof
CN118252943B (en) * 2023-10-25 2024-09-20 常州市智态生创科技有限公司 Short peptide coupling medicine and preparation method and application thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7179784B2 (en) * 2001-07-10 2007-02-20 Massachusetts Institute Of Technology Surfactant peptide nanostructures, and uses thereof
JP2010526091A (en) 2007-04-30 2010-07-29 インテザイン テクノロジーズ， インコーポレイテッド Modification of biological target groups for the treatment of cancer
WO2010108122A1 (en) * 2009-03-20 2010-09-23 Sanford-Burnham Medical Research Institute Targeted delivery of chemotherapeutic agents
SG184345A1 (en) * 2010-03-31 2012-11-29 Agency Science Tech & Res Amphiphilic linear peptide/peptoid and hydrogel comprising the same
SG11201504974PA (en) 2012-12-24 2015-07-30 Agency Science Tech & Res Self-assembling ultrashort peptides modified with bioactive agents by click chemistry

Also Published As

Publication number Publication date
WO2014104974A3 (en) 2016-07-07
US20150352220A1 (en) 2015-12-10
WO2014104974A2 (en) 2014-07-03
US10117946B2 (en) 2018-11-06

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