SG11201502917TA - Control of carbon dioxide levels and ph in small volume reactors - Google Patents
Control of carbon dioxide levels and ph in small volume reactorsInfo
- Publication number
- SG11201502917TA SG11201502917TA SG11201502917TA SG11201502917TA SG11201502917TA SG 11201502917T A SG11201502917T A SG 11201502917TA SG 11201502917T A SG11201502917T A SG 11201502917TA SG 11201502917T A SG11201502917T A SG 11201502917TA SG 11201502917T A SG11201502917T A SG 11201502917TA
- Authority
- SG
- Singapore
- Prior art keywords
- control
- carbon dioxide
- small volume
- dioxide levels
- volume reactors
- Prior art date
Links
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 title 2
- 229910002092 carbon dioxide Inorganic materials 0.000 title 1
- 239000001569 carbon dioxide Substances 0.000 title 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502723—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/24—Gas permeable parts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/26—Constructional details, e.g. recesses, hinges flexible
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/34—Internal compartments or partitions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/06—Nozzles; Sprayers; Spargers; Diffusers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/32—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of substances in solution
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/44—Means for regulation, monitoring, measurement or control, e.g. flow regulation of volume or liquid level
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Dispersion Chemistry (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Carbon And Carbon Compounds (AREA)
- Treating Waste Gases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261719027P | 2012-10-26 | 2012-10-26 | |
| US201361869111P | 2013-08-23 | 2013-08-23 | |
| EP13306462 | 2013-10-23 | ||
| PCT/US2013/066832 WO2014066774A1 (en) | 2012-10-26 | 2013-10-25 | Control of carbon dioxide levels and ph in small volume reactors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201502917TA true SG11201502917TA (en) | 2015-05-28 |
Family
ID=49551567
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201502917TA SG11201502917TA (en) | 2012-10-26 | 2013-10-25 | Control of carbon dioxide levels and ph in small volume reactors |
| SG10201803572UA SG10201803572UA (en) | 2012-10-26 | 2013-10-25 | Control of carbon dioxide levels and ph in small volume reactors |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201803572UA SG10201803572UA (en) | 2012-10-26 | 2013-10-25 | Control of carbon dioxide levels and ph in small volume reactors |
Country Status (10)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102009060489A1 (de) * | 2009-12-29 | 2011-06-30 | Uhde GmbH, 44141 | Vorrichtung und Verfahren zur Regelung der Sauerstoffpermeation durch nicht-poröse Sauerstoffanionen leitende keramische Membranen und deren Verwendung |
| MX373940B (es) | 2012-10-26 | 2020-07-13 | Massachusetts Inst Technology | Control de humedad en reactores quimicos. |
| EP3036317A4 (en) | 2013-08-23 | 2017-04-12 | Massachusetts Institute of Technology | Small volume bioreactors with substantially constant working volumes and associated systems and methods |
| JP6368782B2 (ja) | 2014-05-30 | 2018-08-01 | 株式会社日立製作所 | 医薬品製造支援システム及び医薬品製造支援方法 |
| CN104128152B (zh) * | 2014-08-12 | 2015-09-09 | 青海合杰工贸集团有限责任公司 | 一种调配反应观察装置 |
| DK3595813T3 (da) * | 2017-03-14 | 2021-07-12 | BioGenium Microsystems Oy | System og fremgangsmåde til bestråling af biologisk materiale |
| CN109517738A (zh) * | 2018-12-14 | 2019-03-26 | 杭州奕安济世生物药业有限公司 | 一种调控生物反应器中二氧化碳含量的方法 |
| CN114989977A (zh) * | 2022-06-16 | 2022-09-02 | 中山大学 | 一种用于多细胞相互作用及药物筛选的肿瘤类器官芯片及其制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3080647B2 (ja) * | 1990-10-09 | 2000-08-28 | エーザイ株式会社 | 細胞培養装置 |
| FR2803852B1 (fr) * | 2000-01-17 | 2004-11-05 | Farzin Sarem | Dispositif de culture cellulaire et tissulaire a circulation de fluide de culture controlee |
| EP1499705A2 (en) * | 2002-05-01 | 2005-01-26 | Massachusetts Institute of Technology | Microfermentors for rapid screening and analysis of biochemical processes |
| WO2005026349A1 (ja) * | 2003-09-17 | 2005-03-24 | Mitsubishi Chemical Corporation | 非アミノ有機酸の製造方法 |
| US7367550B2 (en) | 2003-11-18 | 2008-05-06 | Massachusetts Institute Of Technology | Peristaltic mixing and oxygenation system |
| WO2005065419A2 (en) * | 2003-12-29 | 2005-07-21 | Am Biosolutions | Method of culturing cells |
| US20070036690A1 (en) * | 2004-06-07 | 2007-02-15 | Bioprocessors Corp. | Inlet channel volume in a reactor |
| CN1763173A (zh) * | 2005-07-21 | 2006-04-26 | 高春平 | 造血干细胞培养装置和方法 |
| WO2007044699A1 (en) * | 2005-10-07 | 2007-04-19 | Massachusetts Institute Of Technology | Parallel integrated bioreactor device and method |
| US8178318B2 (en) * | 2008-08-06 | 2012-05-15 | Praxair Technology, Inc. | Method for controlling pH, osmolality and dissolved carbon dioxide levels in a mammalian cell culture process to enhance cell viability and biologic product yield |
| EP3643773A1 (en) * | 2009-07-06 | 2020-04-29 | F. Hoffmann-La Roche AG | Method of culturing eukaryotic cells |
-
2013
- 2013-10-25 MX MX2015005284A patent/MX378896B/es unknown
- 2013-10-25 AU AU2013334168A patent/AU2013334168B2/en not_active Ceased
- 2013-10-25 CN CN201710541756.0A patent/CN107267385B/zh active Active
- 2013-10-25 HK HK16101064.1A patent/HK1213006A1/zh unknown
- 2013-10-25 SG SG11201502917TA patent/SG11201502917TA/en unknown
- 2013-10-25 IN IN3093DEN2015 patent/IN2015DN03093A/en unknown
- 2013-10-25 WO PCT/US2013/066832 patent/WO2014066774A1/en active Application Filing
- 2013-10-25 CN CN201380061624.8A patent/CN104870629A/zh active Pending
- 2013-10-25 SG SG10201803572UA patent/SG10201803572UA/en unknown
- 2013-10-25 CA CA2888076A patent/CA2888076C/en active Active
- 2013-10-25 EP EP13786597.8A patent/EP2912157A1/en active Pending
- 2013-10-25 US US14/063,967 patent/US20140127802A1/en not_active Abandoned
-
2015
- 2015-04-24 MX MX2020014123A patent/MX2020014123A/es unknown
-
2016
- 2016-05-20 US US15/161,112 patent/US20170107473A1/en not_active Abandoned
-
2018
- 2018-12-24 AU AU2018286560A patent/AU2018286560B2/en not_active Ceased
-
2020
- 2020-10-09 AU AU2020250287A patent/AU2020250287B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CN107267385A (zh) | 2017-10-20 |
| US20140127802A1 (en) | 2014-05-08 |
| AU2013334168B2 (en) | 2018-10-04 |
| CN107267385B (zh) | 2021-03-12 |
| US20170107473A1 (en) | 2017-04-20 |
| AU2020250287B2 (en) | 2022-07-21 |
| CA2888076A1 (en) | 2014-05-01 |
| MX2015005284A (es) | 2015-11-16 |
| CA2888076C (en) | 2023-08-08 |
| MX378896B (es) | 2025-03-11 |
| AU2013334168A1 (en) | 2015-04-30 |
| MX2020014123A (es) | 2021-03-25 |
| SG10201803572UA (en) | 2018-06-28 |
| AU2018286560A1 (en) | 2019-01-24 |
| IN2015DN03093A (enrdf_load_stackoverflow) | 2015-10-02 |
| AU2018286560B2 (en) | 2020-07-23 |
| WO2014066774A1 (en) | 2014-05-01 |
| EP2912157A1 (en) | 2015-09-02 |
| AU2020250287A1 (en) | 2020-11-05 |
| CN104870629A (zh) | 2015-08-26 |
| HK1213006A1 (zh) | 2016-06-24 |
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