SG11201408138XA - Method for producing a collagen membrane and uses thereof - Google Patents

Method for producing a collagen membrane and uses thereof

Info

Publication number
SG11201408138XA
SG11201408138XA SG11201408138XA SG11201408138XA SG11201408138XA SG 11201408138X A SG11201408138X A SG 11201408138XA SG 11201408138X A SG11201408138X A SG 11201408138XA SG 11201408138X A SG11201408138X A SG 11201408138XA SG 11201408138X A SG11201408138X A SG 11201408138XA
Authority
SG
Singapore
Prior art keywords
collagen
lllll
international
iii
llll
Prior art date
Application number
SG11201408138XA
Inventor
Ming-Hao Zheng
Original Assignee
Orthocell Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2012902458A external-priority patent/AU2012902458A0/en
Application filed by Orthocell Ltd filed Critical Orthocell Ltd
Publication of SG11201408138XA publication Critical patent/SG11201408138XA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1136—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by reversible modification of the secondary, tertiary or quarternary structure, e.g. using denaturating or stabilising agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/18—Internal ear or nose parts, e.g. ear-drums
    • A61F2002/183—Ear parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/14—Materials or treatment for tissue regeneration for ear reconstruction or ear implants, e.g. implantable hearing aids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking

Abstract

(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 19 December 2013 (19.12.2013) WIPOIPCT (10) International Publication Number WO 2013/185173 A1 (51) International Patent Classification: A61L 27/24 (2006.01) A61F2/18 (2006.01) (21) International Application Number: (22) International Filing Date: (25) Filing Language: (26) Publication Language: PCT/AU2013/000621 12 June 2013 (12.06.2013) English English (30) Priority Data: 2012902458 12 June 2012 (12.06.2012) (71) Applicant: THE UNIVERSITY OF WESTERN AUS­ TRALIA [AU/AU]; Nedlands, Western Australia 6907 (AU). (72) Inventor: ZHENG, Ming-Hao; 2 Kingsland Avenue, City Beach, Western Australia 6015 (AU). (74) Agent: GRIFFITH HACK; Level 19, 109 St Georges Terrace, Perth, Western Australia 6000 (AU). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. Au (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). [Continued on next page] (54) Title: METHOD FOR PRODUCING A COLLAGEN MEMBRANE AND USES THEREOF l> i-H oo i-H o CJ o & Figure 1 (57) Abstract: The present invention relates to a method of producing a col­ lagen membrane that has particular mechanical properties. In particular, the present invention relates to a method A of producing a collagen membrane comprising the steps of (i) isolating collagen-containing a tissue and incub - ating same in an ethanol solution; (ii) incubating the collagen-containing tis - sue from step (i) in a first solution comprising an inorganic salt and an an­ ionic surfactant in order to denature non-collagenous proteins contained therein; (iii) incubating the collagen- containing tissue produced in step (ii) in second solution comprising a an inorganic acid until the collagen in said material is denatured; and (iv) incubating the collagen-containing tissue pro­ duced in step (iii) in a third solution comprising an inorganic acid with sim­ ultaneous mechanical stimulation for sufficient time to enable the collagen bundles in said collagen- containing tissue to align; wherein the mechanical stimulation comprises applying tension cyclically to the collagen-containing tissue. WO 2013/185173 A11 lllll llllllll II llllll III lllll lllll III III III lllll lllll lllll lllll llll lllll llll lllllll llll llll Published: — with international search report (Art. 21(3))
SG11201408138XA 2012-06-12 2013-06-12 Method for producing a collagen membrane and uses thereof SG11201408138XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2012902458A AU2012902458A0 (en) 2012-06-12 Scaffold For Tympanic Membrane Reconstruction
PCT/AU2013/000621 WO2013185173A1 (en) 2012-06-12 2013-06-12 Method for producing a collagen membrane and uses thereof

Publications (1)

Publication Number Publication Date
SG11201408138XA true SG11201408138XA (en) 2015-01-29

Family

ID=49757327

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201408138XA SG11201408138XA (en) 2012-06-12 2013-06-12 Method for producing a collagen membrane and uses thereof

Country Status (12)

Country Link
US (5) US9096688B2 (en)
EP (1) EP2858691B1 (en)
JP (2) JP6105060B2 (en)
CN (1) CN104684593B (en)
AU (2) AU2013273923C1 (en)
CA (1) CA2876064C (en)
ES (1) ES2676545T3 (en)
HK (1) HK1209062A1 (en)
MX (1) MX359881B (en)
NZ (1) NZ702942A (en)
SG (1) SG11201408138XA (en)
WO (1) WO2013185173A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX359881B (en) * 2012-06-12 2018-10-15 Orthocell Ltd Method for producing a collagen membrane and uses thereof.
AU2015330961B2 (en) 2014-10-10 2017-12-07 Orthocell Limited Collagen construct and method for producing the collagen construct
EP3643329A1 (en) * 2014-10-10 2020-04-29 Orthocell Limited Sutureless repair of soft tissue
JP2018514248A (en) 2015-03-23 2018-06-07 ボーナ スーポート アーベー Biphasic ceramic bone substitute
RU2593898C1 (en) * 2015-04-13 2016-08-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Астраханский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ГБОУ ВПО Астраханский ГМУ Минздрава России) Method for mastoid repair during repeated sanitising operations on ear
CN108837181A (en) * 2018-06-20 2018-11-20 罗国球 A kind of bionical collagem membrane and preparation method thereof of high intensity
CN113874192B (en) * 2019-02-01 2024-01-02 恩博迪股份有限公司 Microfluidic extrusion
CN117398528A (en) * 2023-10-31 2024-01-16 广州曼翔医药有限公司 Middle ear ventilation drainage tube and preparation method and application thereof

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US20050186283A1 (en) * 1997-10-10 2005-08-25 Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie Collagen carrier of therapeutic genetic material, and method
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Also Published As

Publication number Publication date
WO2013185173A1 (en) 2013-12-19
EP2858691A4 (en) 2016-01-13
MX2014015233A (en) 2015-06-23
JP2017136384A (en) 2017-08-10
CA2876064A1 (en) 2013-12-19
EP2858691A1 (en) 2015-04-15
ES2676545T3 (en) 2018-07-20
EP2858691B1 (en) 2018-05-16
US20230190998A1 (en) 2023-06-22
AU2015258323A1 (en) 2015-12-10
CN104684593A (en) 2015-06-03
HK1209062A1 (en) 2016-03-24
CA2876064C (en) 2020-07-07
CN104684593B (en) 2016-07-06
AU2015258323B2 (en) 2017-06-01
US20140288271A1 (en) 2014-09-25
JP6105060B2 (en) 2017-03-29
NZ702942A (en) 2017-01-27
AU2013273923C1 (en) 2016-11-03
JP2015522332A (en) 2015-08-06
US10314939B2 (en) 2019-06-11
AU2013273923A1 (en) 2015-01-22
US20150283299A1 (en) 2015-10-08
US20210093750A1 (en) 2021-04-01
AU2013273923B2 (en) 2015-08-20
US20190262501A1 (en) 2019-08-29
MX359881B (en) 2018-10-15
US10888638B2 (en) 2021-01-12
JP6648056B2 (en) 2020-02-14
US9096688B2 (en) 2015-08-04

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