SG11201407649RA - Method for treating non-small cell lung cancer - Google Patents
Method for treating non-small cell lung cancerInfo
- Publication number
- SG11201407649RA SG11201407649RA SG11201407649RA SG11201407649RA SG11201407649RA SG 11201407649R A SG11201407649R A SG 11201407649RA SG 11201407649R A SG11201407649R A SG 11201407649RA SG 11201407649R A SG11201407649R A SG 11201407649RA SG 11201407649R A SG11201407649R A SG 11201407649RA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- lung cancer
- small cell
- cell lung
- treating
- Prior art date
Links
- 208000002154 non-small cell lung carcinoma Diseases 0.000 title abstract 5
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 190000008236 Carboplatin Chemical compound 0.000 abstract 3
- 229930012538 Paclitaxel Natural products 0.000 abstract 3
- 229960004562 carboplatin Drugs 0.000 abstract 3
- 230000001394 metastastic effect Effects 0.000 abstract 3
- 206010061289 metastatic neoplasm Diseases 0.000 abstract 3
- 239000002773 nucleotide Substances 0.000 abstract 3
- 125000003729 nucleotide group Chemical group 0.000 abstract 3
- 229960001592 paclitaxel Drugs 0.000 abstract 3
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 abstract 3
- 206010061818 Disease progression Diseases 0.000 abstract 2
- 108091034117 Oligonucleotide Proteins 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- RCFZILUHCNXXFY-DEDWCYLFSA-N custirsen Chemical compound N1([C@@H]2O[C@H](COP(O)(=S)O[C@H]3[C@H]([C@@H](O[C@@H]3COP(S)(=O)O[C@H]3[C@H]([C@@H](O[C@@H]3COP(O)(=S)O[C@H]3[C@H]([C@@H](O[C@@H]3COP(O)(=S)O[C@@H]3[C@H](O[C@H](C3)N3C4=NC=NC(N)=C4N=C3)COP(O)(=S)O[C@@H]3[C@H](O[C@H](C3)N3C(N=C(N)C=C3)=O)COP(O)(=S)O[C@@H]3[C@H](O[C@H](C3)N3C(NC(=O)C(C)=C3)=O)COP(O)(=S)O[C@@H]3[C@H](O[C@H](C3)N3C(NC(=O)C(C)=C3)=O)COP(O)(=S)O[C@@H]3[C@H](O[C@H](C3)N3C(N=C(N)C=C3)=O)COP(O)(=S)O[C@@H]3[C@H](O[C@H](C3)N3C(NC(=O)C(C)=C3)=O)COP(O)(=S)O[C@@H]3[C@H](O[C@H](C3)N3C4=C(C(NC(N)=N4)=O)N=C3)COP(O)(=S)O[C@@H]3[C@H](O[C@H](C3)N3C4=NC=NC(N)=C4N=C3)COP(O)(=S)O[C@@H]3[C@H](O[C@H](C3)N3C4=C(C(NC(N)=N4)=O)N=C3)COP(O)(=S)O[C@@H]3[C@H](O[C@H](C3)N3C4=NC=NC(N)=C4N=C3)COP(O)(=S)O[C@@H]3[C@H](O[C@H](C3)N3C(N=C(N)C=C3)=O)COP(O)(=S)O[C@@H]3[C@H](O[C@H](C3)N3C4=C(C(NC(N)=N4)=O)N=C3)COP(O)(=S)O[C@@H]3[C@H](O[C@H](C3)N3C4=NC=NC(N)=C4N=C3)COP(O)(=S)O[C@H]3[C@H]([C@@H](O[C@@H]3COP(O)(=S)O[C@H]3[C@H]([C@@H](O[C@@H]3COP(O)(=S)O[C@H]3[C@H]([C@@H](O[C@@H]3COP(O)(=S)O[C@H]3[C@H]([C@@H](O[C@@H]3CO)N3C(N=C(N)C(C)=C3)=O)OCCOC)N3C4=NC=NC(N)=C4N=C3)OCCOC)N3C4=C(C(NC(N)=N4)=O)N=C3)OCCOC)N3C(N=C(N)C(C)=C3)=O)OCCOC)N3C(NC(=O)C(C)=C3)=O)OCCOC)N3C(N=C(N)C(C)=C3)=O)OCCOC)N3C4=NC=NC(N)=C4N=C3)OCCOC)[C@@H](O)[C@H]2OCCOC)C=C(C)C(=O)NC1=O RCFZILUHCNXXFY-DEDWCYLFSA-N 0.000 abstract 2
- 229950001605 custirsen Drugs 0.000 abstract 2
- 230000005750 disease progression Effects 0.000 abstract 2
- 230000003442 weekly effect Effects 0.000 abstract 2
- LRSASMSXMSNRBT-UHFFFAOYSA-N 5-methylcytosine Chemical class CC1=CNC(=O)N=C1N LRSASMSXMSNRBT-UHFFFAOYSA-N 0.000 abstract 1
- ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 abstract 1
- 238000002512 chemotherapy Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229960003668 docetaxel Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 230000008520 organization Effects 0.000 abstract 1
- 230000004083 survival effect Effects 0.000 abstract 1
- RYYWUUFWQRZTIU-UHFFFAOYSA-K thiophosphate Chemical compound [O-]P([O-])([O-])=S RYYWUUFWQRZTIU-UHFFFAOYSA-K 0.000 abstract 1
- 231100000402 unacceptable toxicity Toxicity 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57423—Specifically defined cancers of lung
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261649092P | 2012-05-18 | 2012-05-18 | |
| PCT/US2013/041652 WO2013173757A1 (en) | 2012-05-18 | 2013-05-17 | Method for treating non-small cell lung cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201407649RA true SG11201407649RA (en) | 2014-12-30 |
Family
ID=49581824
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201407649RA SG11201407649RA (en) | 2012-05-18 | 2013-05-17 | Method for treating non-small cell lung cancer |
Country Status (17)
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1163254T3 (da) | 1999-02-26 | 2008-06-09 | Univ British Columbia | TRPM-2 antisense-behandling |
| US7569551B2 (en) | 2000-02-25 | 2009-08-04 | The University Of British Columbia | Chemo- and radiation-sensitization of cancer by antisense TRPM-2 oligodeoxynucleotides |
| EP2569618B1 (en) | 2010-05-08 | 2017-03-01 | The Regents of the University of California | Sem scanner sensing apparatus, system and methodology for early detection of ulcers |
| EP2685990A4 (en) | 2011-03-15 | 2014-09-17 | Univ British Columbia | COMBINATION OF AN ANTI-CLUSTERIN OLIGONUCLEOTIDE AND AN HSP90 INHIBITOR FOR THE TREATMENT OF PROSTATE CANCER |
| CN104473973B (zh) * | 2014-12-19 | 2015-08-05 | 山东创新药物研发有限公司 | 一株戈氏梭菌驯化株的应用 |
| WO2016172263A1 (en) | 2015-04-24 | 2016-10-27 | Bruin Biometrics Llc | Apparatus and methods for determining damaged tissue using sub-epidermal moisture measurements |
| CN118177725A (zh) | 2017-02-03 | 2024-06-14 | 布鲁恩医疗创新有限责任公司 | 糖尿病足溃疡易感性的测量 |
| EP3515298A4 (en) | 2017-02-03 | 2020-03-11 | Bruin Biometrics, LLC | MEASUREMENT OF EDEMA |
| PL3515296T3 (pl) | 2017-02-03 | 2024-03-25 | Bbi Medical Innovations, Llc | Pomiar żywotności tkanki |
| JP7209713B2 (ja) | 2017-11-16 | 2023-01-20 | ブルーイン、バイオメトリクス、リミテッド、ライアビリティー、カンパニー | 表皮下水分値を用いた褥瘡性潰瘍の戦略的処置 |
| WO2019136287A1 (en) * | 2018-01-05 | 2019-07-11 | LifeUnit Inc. | Adjuvant chemicals that prevent drug tolerance and persister formation by bacteria |
| PT3749181T (pt) | 2018-02-09 | 2024-05-15 | Bruin Biometrics Llc | Deteção de lesões nos tecidos |
| IL290883B2 (en) | 2018-10-11 | 2024-02-01 | Bruin Biometrics Llc | Device with disposable element |
| US11642075B2 (en) | 2021-02-03 | 2023-05-09 | Bruin Biometrics, Llc | Methods of treating deep and early-stage pressure induced tissue damage |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6900187B2 (en) * | 1999-02-26 | 2005-05-31 | The University Of British Columbia | TRPM-2 antisense therapy using an oligonucleotide having 2′-O-(2-methoxy)ethyl modifications |
| US20060024692A1 (en) * | 2002-09-30 | 2006-02-02 | Oncotherapy Science, Inc. | Method for diagnosing non-small cell lung cancers |
| US8710020B2 (en) * | 2004-04-02 | 2014-04-29 | The University Of British Columbia | Clusterin antisense therapy for treatment of cancer |
| EP2300825A4 (en) * | 2008-06-18 | 2012-04-25 | Abbott Lab | P / GF 1 COMPARATIVE DIAGNOSTIC PROCEDURES AND PRODUCTS |
| SG194931A1 (en) * | 2011-05-19 | 2013-12-30 | Teva Pharma | Method for treating non-small cell lung cancer |
-
2013
- 2013-05-16 UY UY0001034812A patent/UY34812A/es not_active Application Discontinuation
- 2013-05-17 AR ARP130101729A patent/AR091090A1/es unknown
- 2013-05-17 TW TW102117597A patent/TW201402132A/zh unknown
- 2013-05-17 US US13/896,737 patent/US20130310440A1/en not_active Abandoned
- 2013-05-17 WO PCT/US2013/041652 patent/WO2013173757A1/en active Application Filing
- 2013-05-17 CN CN201380030309.9A patent/CN104684564A/zh active Pending
- 2013-05-17 CA CA2874092A patent/CA2874092A1/en not_active Abandoned
- 2013-05-17 SG SG11201407649RA patent/SG11201407649RA/en unknown
- 2013-05-17 AU AU2013262589A patent/AU2013262589A1/en not_active Abandoned
- 2013-05-17 BR BR112014028787A patent/BR112014028787A2/pt not_active IP Right Cessation
- 2013-05-17 KR KR20147035652A patent/KR20150024843A/ko not_active Withdrawn
- 2013-05-17 IN IN10390DEN2014 patent/IN2014DN10390A/en unknown
- 2013-05-17 EP EP13791341.4A patent/EP2849761A1/en not_active Withdrawn
- 2013-05-17 JP JP2015512895A patent/JP2015522542A/ja active Pending
- 2013-05-17 EA EA201492148A patent/EA201492148A1/ru unknown
-
2014
- 2014-11-02 IL IL235459A patent/IL235459A0/en unknown
- 2014-11-18 PH PH12014502569A patent/PH12014502569A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN104684564A (zh) | 2015-06-03 |
| TW201402132A (zh) | 2014-01-16 |
| AU2013262589A1 (en) | 2015-01-22 |
| AR091090A1 (es) | 2014-12-30 |
| US20130310440A1 (en) | 2013-11-21 |
| PH12014502569A1 (en) | 2015-01-21 |
| WO2013173757A8 (en) | 2015-04-30 |
| KR20150024843A (ko) | 2015-03-09 |
| UY34812A (es) | 2013-12-31 |
| IN2014DN10390A (enrdf_load_stackoverflow) | 2015-08-14 |
| JP2015522542A (ja) | 2015-08-06 |
| BR112014028787A2 (pt) | 2017-06-27 |
| IL235459A0 (en) | 2014-12-31 |
| EA201492148A1 (ru) | 2015-04-30 |
| EP2849761A1 (en) | 2015-03-25 |
| CA2874092A1 (en) | 2013-11-21 |
| WO2013173757A1 (en) | 2013-11-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SG11201407649RA (en) | Method for treating non-small cell lung cancer | |
| SG11201811431VA (en) | Multispecific antibodies against cd40 and cd137 | |
| SG11201407859YA (en) | Methods of treating cancer using pd-l1 axis binding antagonists and vegf antagonists | |
| SG11201408174UA (en) | Antibody formulation | |
| SG11201908547VA (en) | Hydrogel cross-linked hyaluronic acid prodrug compositions and methods | |
| SG11201408261UA (en) | Syringe | |
| SG11201808693WA (en) | Anti-il-33 antibodies, compositions, methods and uses thereof | |
| SG11201804170RA (en) | Polycyclic tlr7/8 antagonists and use thereof in the treatment of immune disorders | |
| SG11201811432WA (en) | Rna for cancer therapy | |
| SG11201806340YA (en) | Zika virus vaccine | |
| SG11201804729RA (en) | Methods and compositions for treating a serpinc1-associated disorder | |
| SG11201804398XA (en) | Method for producing rna molecule compositions | |
| SG11201407580YA (en) | Composition comprising two antibodies engineered to have reduced and increased effector function | |
| SG11201408810TA (en) | Methods of treating arthritis | |
| SG11201407537YA (en) | Mutant selectivity and combinations of a phosphoinositide 3 kinase inhibitor compound and chemotherapeutic agents for the treatment of cancer | |
| SG11201500005SA (en) | Pyrimidine pyrazolyl derivatives | |
| SG11201804577RA (en) | Fgf21 variants | |
| SG11201408460UA (en) | Inhibitors of the mir-15 family of micro-rnas | |
| SG11201900021PA (en) | Methods and compositions for the treatment of cancer | |
| SG11201908326YA (en) | Methods of treating neurodegenerative diseases | |
| SG11201407512VA (en) | High-concentration monoclonal antibody formulations | |
| SG11201406973PA (en) | Complement pathway modulators and uses thereof | |
| SG11201407860PA (en) | Exendin-4 peptide analogues | |
| SG11201908487YA (en) | Mitoriboscins: mitochondrial-based therapeutics targeting cancer cells, bacteria, and pathogenic yeast | |
| SG11201906436VA (en) | Novel heterocyclic compound, its preparation method, and pharmaceutical composition comprising the same |