AR091090A1 - Metodo para el tratamiento del cancer de pulmon de celulas no pequeñas - Google Patents
Metodo para el tratamiento del cancer de pulmon de celulas no pequeñasInfo
- Publication number
- AR091090A1 AR091090A1 ARP130101729A ARP130101729A AR091090A1 AR 091090 A1 AR091090 A1 AR 091090A1 AR P130101729 A ARP130101729 A AR P130101729A AR P130101729 A ARP130101729 A AR P130101729A AR 091090 A1 AR091090 A1 AR 091090A1
- Authority
- AR
- Argentina
- Prior art keywords
- small cell
- treatment
- human patient
- nucleotides
- metastatic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57423—Specifically defined cancers of lung
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Food Science & Technology (AREA)
- Hospice & Palliative Care (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente proporciona los métodos para el tratamiento de un paciente humano quien padece cáncer de pulmón de células no pequeñas metastásico o avanzado, no resecable, cuyos métodos comprenden administrar periódicamente al paciente humano quimioterapia que comprende una cantidad de docetaxel y 640 mg de un oligonucleótido anti-clusterina que tiene la secuencia CAGCAGCAGAGTCTTCATCAT (Seq. ID Nº 1), donde el oligonucleótido anti-clusterina tiene una columna vertebral fósforotioato a su través, tiene mitades de azúcar de los nucleótidos 1 - 4 y 18 - 21 que portan modificaciones 2-O-metoxietilo, tiene los nucleótidos 5 - 17 que son 2desoxinucleótidos y tiene 5-metilcitosinas en los nucleótidos 1, 4 y 19, tratando así al paciente humano que padece de cáncer de pulmón de célula no pequeña metastásico o avanzado, no resecable. También proporciona composiciones y combinaciones, paquetes y usos de los mismos para el tratamiento de un paciente humano que padece de cáncer de pulmón de célula no pequeña metastásico o avanzado, no resecable.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261649092P | 2012-05-18 | 2012-05-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR091090A1 true AR091090A1 (es) | 2014-12-30 |
Family
ID=49581824
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP130101729A AR091090A1 (es) | 2012-05-18 | 2013-05-17 | Metodo para el tratamiento del cancer de pulmon de celulas no pequeñas |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20130310440A1 (es) |
| EP (1) | EP2849761A1 (es) |
| JP (1) | JP2015522542A (es) |
| KR (1) | KR20150024843A (es) |
| CN (1) | CN104684564A (es) |
| AR (1) | AR091090A1 (es) |
| AU (1) | AU2013262589A1 (es) |
| BR (1) | BR112014028787A2 (es) |
| CA (1) | CA2874092A1 (es) |
| EA (1) | EA201492148A1 (es) |
| IL (1) | IL235459A0 (es) |
| IN (1) | IN2014DN10390A (es) |
| PH (1) | PH12014502569A1 (es) |
| SG (1) | SG11201407649RA (es) |
| TW (1) | TW201402132A (es) |
| UY (1) | UY34812A (es) |
| WO (1) | WO2013173757A1 (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU767133B2 (en) | 1999-02-26 | 2003-10-30 | University Of British Columbia, The | TRPM-2 antisense therapy |
| US7569551B2 (en) | 2000-02-25 | 2009-08-04 | The University Of British Columbia | Chemo- and radiation-sensitization of cancer by antisense TRPM-2 oligodeoxynucleotides |
| BR122021016044B1 (pt) | 2010-05-08 | 2022-07-19 | Bruin Biometrics, Llc | Aparelho para detecção de umidade subepidérmica (sem) |
| KR20140038388A (ko) | 2011-03-15 | 2014-03-28 | 더 유니버시티 오브 브리티쉬 콜롬비아 | 전립선암의 치료를 위한 항-클러스테린 올리고뉴클레오타이드와 hsp90 저해제의 병용 |
| CN104473973B (zh) * | 2014-12-19 | 2015-08-05 | 山东创新药物研发有限公司 | 一株戈氏梭菌驯化株的应用 |
| AU2016250527B2 (en) | 2015-04-24 | 2021-01-14 | Bruin Biometrics Llc | Apparatus and methods for determining damaged tissue using sub-epidermal moisture measurements |
| GB2600253B (en) | 2017-02-03 | 2022-11-23 | Bruin Biometrics Llc | Measurement of edema |
| GB2591707B (en) | 2017-02-03 | 2021-11-17 | Bruin Biometrics Llc | Measurement of susceptibility to diabetic foot ulcers |
| MX2019004925A (es) | 2017-02-03 | 2019-06-20 | Bruin Biometrics Llc | Medicion de viabilidad tisular. |
| EP3562392A4 (en) | 2017-11-16 | 2021-06-09 | Bruin Biometrics, LLC | STRATEGIC TREATMENT OF DECUBITUS SLEEP USING SUB-EPIDERMAL MOISTURE VALUES |
| US20190211044A1 (en) * | 2018-01-05 | 2019-07-11 | LifeUnit Inc. | Adjuvant Chemicals that Prevent Drug Tolerance and Persister Formation by Bacteria |
| GB2584226B (en) | 2018-02-09 | 2022-06-22 | Bruin Biometrics Llc | Detection of tissue damage |
| US10950960B2 (en) | 2018-10-11 | 2021-03-16 | Bruin Biometrics, Llc | Device with disposable element |
| WO2022169850A1 (en) | 2021-02-03 | 2022-08-11 | Bruin Biometrics, Llc | Methods of treating deep and early-stage pressure induced tissue damage |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6900187B2 (en) * | 1999-02-26 | 2005-05-31 | The University Of British Columbia | TRPM-2 antisense therapy using an oligonucleotide having 2′-O-(2-methoxy)ethyl modifications |
| US20060024692A1 (en) * | 2002-09-30 | 2006-02-02 | Oncotherapy Science, Inc. | Method for diagnosing non-small cell lung cancers |
| US8710020B2 (en) * | 2004-04-02 | 2014-04-29 | The University Of British Columbia | Clusterin antisense therapy for treatment of cancer |
| CA2728449A1 (en) * | 2008-06-18 | 2009-12-23 | Abbott Laboratories | P/gf-1 companion diagnostic methods and products |
| KR20140034838A (ko) * | 2011-05-19 | 2014-03-20 | 테바 파마슈티컬 인더스트리즈 리미티드 | 비소세포 폐암을 치료하는 방법 |
-
2013
- 2013-05-16 UY UY0001034812A patent/UY34812A/es not_active Application Discontinuation
- 2013-05-17 CN CN201380030309.9A patent/CN104684564A/zh active Pending
- 2013-05-17 JP JP2015512895A patent/JP2015522542A/ja active Pending
- 2013-05-17 EA EA201492148A patent/EA201492148A1/ru unknown
- 2013-05-17 TW TW102117597A patent/TW201402132A/zh unknown
- 2013-05-17 AR ARP130101729A patent/AR091090A1/es unknown
- 2013-05-17 SG SG11201407649RA patent/SG11201407649RA/en unknown
- 2013-05-17 BR BR112014028787A patent/BR112014028787A2/pt not_active IP Right Cessation
- 2013-05-17 AU AU2013262589A patent/AU2013262589A1/en not_active Abandoned
- 2013-05-17 WO PCT/US2013/041652 patent/WO2013173757A1/en active Application Filing
- 2013-05-17 IN IN10390DEN2014 patent/IN2014DN10390A/en unknown
- 2013-05-17 KR KR20147035652A patent/KR20150024843A/ko not_active Application Discontinuation
- 2013-05-17 EP EP13791341.4A patent/EP2849761A1/en not_active Withdrawn
- 2013-05-17 CA CA2874092A patent/CA2874092A1/en not_active Abandoned
- 2013-05-17 US US13/896,737 patent/US20130310440A1/en not_active Abandoned
-
2014
- 2014-11-02 IL IL235459A patent/IL235459A0/en unknown
- 2014-11-18 PH PH12014502569A patent/PH12014502569A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR112014028787A2 (pt) | 2017-06-27 |
| KR20150024843A (ko) | 2015-03-09 |
| EA201492148A1 (ru) | 2015-04-30 |
| IL235459A0 (en) | 2014-12-31 |
| AU2013262589A1 (en) | 2015-01-22 |
| EP2849761A1 (en) | 2015-03-25 |
| TW201402132A (zh) | 2014-01-16 |
| WO2013173757A1 (en) | 2013-11-21 |
| CN104684564A (zh) | 2015-06-03 |
| CA2874092A1 (en) | 2013-11-21 |
| SG11201407649RA (en) | 2014-12-30 |
| JP2015522542A (ja) | 2015-08-06 |
| IN2014DN10390A (es) | 2015-08-14 |
| PH12014502569A1 (en) | 2015-01-21 |
| US20130310440A1 (en) | 2013-11-21 |
| UY34812A (es) | 2013-12-31 |
| WO2013173757A8 (en) | 2015-04-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR091090A1 (es) | Metodo para el tratamiento del cancer de pulmon de celulas no pequeñas | |
| AU2018256508A1 (en) | Individualized vaccines for cancer | |
| WO2013086444A3 (en) | Methods for treating progeroid laminopathies using oligonucleotide analogues targeting human lmna | |
| EP3800255A3 (en) | Rna-guided transcriptional regulation and methods of using the same for the treatment of back pain | |
| AR086514A1 (es) | Metodo de tratamiento del cancer de pulmon de celulas no pequeñas, composicion, uso, envase | |
| MX2019010601A (es) | Terapia de combinacion para tratar cancer. | |
| EA201490563A1 (ru) | Антисмысловые олигонуклеотиды для лечения врожденного амавроза лебера | |
| WO2011038160A3 (en) | Compositions and methods for silencing genes expressed in cancer | |
| SA519401379B1 (ar) | علاج فيروس مرتبط بغدة لمرض هنتنجتون | |
| CA3010582A1 (en) | Extracellular vesicles for agent delivery | |
| WO2011163499A3 (en) | Treatment of sodium channel, voltage-gated, alpha subunit (scna) related diseases by inhibition of natural antisense transcript to scna | |
| MX359548B (es) | Agentes de iarn modificados. | |
| MX2011009751A (es) | Tratamiento de enfermedades relacionadas con factor nuclear (eritroide derivado 2) tipo 2 (nrf2) por inhibicion del transcrito antisentido natural a nrf2. | |
| WO2012009402A3 (en) | Treatment of discs large homolog (dlg) related diseases by inhibition of natural antisense transcript to dlg | |
| WO2012054723A3 (en) | Treatment of alpha-l-iduronidase (idua) related diseases by inhibition of natural antisense transcript to idua | |
| EP2700708A3 (en) | Enhancing the T-cell stimulatory capacity of human antigen presenting cells in vitro and in vivo and its use in vaccination | |
| WO2011091390A3 (en) | Treatment of rnase h1 related diseases by inhibition of natural antisense transcript to rnase h1 | |
| EA201590070A1 (ru) | ИНГИБИТОРЫ МИКРОРНК СЕМЕЙСТВА miR-15 | |
| WO2012024396A3 (en) | Compositions and methods for delivering nucleic acid molecules and treating cancer | |
| NZ630914A (en) | Methods of treating diabetes and/or promoting survival of pancreatic islets after transplantation | |
| MX2024000277A (es) | Microarns modificados con 5-halouracilo y su uso en el tratamiento del cancer. | |
| EA201791471A1 (ru) | Способы применения антисмысловых олигонуклеотидов smad7 | |
| NZ741841A (en) | Antisense oligonucleotides for use in treating alzheimer’s disease | |
| MX2015012063A (es) | Oligonucleotidos antisentido para el tratamiento de celulas madre del cancer. | |
| AR095416A1 (es) | Tratamiento con cutirsen que presenta una toxicidad reducida |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |