AR091090A1 - Metodo para el tratamiento del cancer de pulmon de celulas no pequeñas - Google Patents
Metodo para el tratamiento del cancer de pulmon de celulas no pequeñasInfo
- Publication number
- AR091090A1 AR091090A1 ARP130101729A ARP130101729A AR091090A1 AR 091090 A1 AR091090 A1 AR 091090A1 AR P130101729 A ARP130101729 A AR P130101729A AR P130101729 A ARP130101729 A AR P130101729A AR 091090 A1 AR091090 A1 AR 091090A1
- Authority
- AR
- Argentina
- Prior art keywords
- small cell
- treatment
- human patient
- nucleotides
- metastatic
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57423—Specifically defined cancers of lung
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Food Science & Technology (AREA)
- Hospice & Palliative Care (AREA)
- Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente proporciona los métodos para el tratamiento de un paciente humano quien padece cáncer de pulmón de células no pequeñas metastásico o avanzado, no resecable, cuyos métodos comprenden administrar periódicamente al paciente humano quimioterapia que comprende una cantidad de docetaxel y 640 mg de un oligonucleótido anti-clusterina que tiene la secuencia CAGCAGCAGAGTCTTCATCAT (Seq. ID Nº 1), donde el oligonucleótido anti-clusterina tiene una columna vertebral fósforotioato a su través, tiene mitades de azúcar de los nucleótidos 1 - 4 y 18 - 21 que portan modificaciones 2-O-metoxietilo, tiene los nucleótidos 5 - 17 que son 2desoxinucleótidos y tiene 5-metilcitosinas en los nucleótidos 1, 4 y 19, tratando así al paciente humano que padece de cáncer de pulmón de célula no pequeña metastásico o avanzado, no resecable. También proporciona composiciones y combinaciones, paquetes y usos de los mismos para el tratamiento de un paciente humano que padece de cáncer de pulmón de célula no pequeña metastásico o avanzado, no resecable.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261649092P | 2012-05-18 | 2012-05-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR091090A1 true AR091090A1 (es) | 2014-12-30 |
Family
ID=49581824
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP130101729A AR091090A1 (es) | 2012-05-18 | 2013-05-17 | Metodo para el tratamiento del cancer de pulmon de celulas no pequeñas |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20130310440A1 (es) |
| EP (1) | EP2849761A1 (es) |
| JP (1) | JP2015522542A (es) |
| KR (1) | KR20150024843A (es) |
| CN (1) | CN104684564A (es) |
| AR (1) | AR091090A1 (es) |
| AU (1) | AU2013262589A1 (es) |
| BR (1) | BR112014028787A2 (es) |
| CA (1) | CA2874092A1 (es) |
| EA (1) | EA201492148A1 (es) |
| IL (1) | IL235459A0 (es) |
| IN (1) | IN2014DN10390A (es) |
| PH (1) | PH12014502569A1 (es) |
| SG (1) | SG11201407649RA (es) |
| TW (1) | TW201402132A (es) |
| UY (1) | UY34812A (es) |
| WO (1) | WO2013173757A1 (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE385237T1 (de) | 1999-02-26 | 2008-02-15 | Univ British Columbia | Antisense-therapie für trpm-2 |
| US7569551B2 (en) | 2000-02-25 | 2009-08-04 | The University Of British Columbia | Chemo- and radiation-sensitization of cancer by antisense TRPM-2 oligodeoxynucleotides |
| WO2011143071A2 (en) | 2010-05-08 | 2011-11-17 | The Regents Of The University Of California | Sem scanner sensing apparatus, system and methodology for early detection of ulcers |
| KR20140038388A (ko) | 2011-03-15 | 2014-03-28 | 더 유니버시티 오브 브리티쉬 콜롬비아 | 전립선암의 치료를 위한 항-클러스테린 올리고뉴클레오타이드와 hsp90 저해제의 병용 |
| CN104473973B (zh) * | 2014-12-19 | 2015-08-05 | 山东创新药物研发有限公司 | 一株戈氏梭菌驯化株的应用 |
| CA2982249C (en) | 2015-04-24 | 2019-12-31 | Bruin Biometrics, Llc | Apparatus and methods for determining damaged tissue using sub-epidermal moisture measurements |
| AU2018217187B2 (en) | 2017-02-03 | 2020-01-02 | Bruin Biometrics, Llc | Measurement of edema |
| GB2600266B (en) | 2017-02-03 | 2023-03-01 | Bruin Biometrics Llc | Measurement of tissue viability |
| KR102283395B1 (ko) | 2017-02-03 | 2021-07-30 | 브루인 바이오메트릭스, 엘엘씨 | 당뇨병성 족부 궤양에 대한 감수성의 측정 |
| WO2019099812A1 (en) * | 2017-11-16 | 2019-05-23 | Bruin Biometrics, Llc | Providing a continuity of care across multiple care settings |
| US20190211044A1 (en) * | 2018-01-05 | 2019-07-11 | LifeUnit Inc. | Adjuvant Chemicals that Prevent Drug Tolerance and Persister Formation by Bacteria |
| CA3090395A1 (en) | 2018-02-09 | 2019-08-15 | Bruin Biometrics, Llc | Detection of tissue damage |
| LT3861601T (lt) | 2018-10-11 | 2024-03-12 | Bruin Biometrics, Llc | Prietaisas su vienkartiniu elementu |
| US11642075B2 (en) | 2021-02-03 | 2023-05-09 | Bruin Biometrics, Llc | Methods of treating deep and early-stage pressure induced tissue damage |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6900187B2 (en) * | 1999-02-26 | 2005-05-31 | The University Of British Columbia | TRPM-2 antisense therapy using an oligonucleotide having 2′-O-(2-methoxy)ethyl modifications |
| US20060024692A1 (en) * | 2002-09-30 | 2006-02-02 | Oncotherapy Science, Inc. | Method for diagnosing non-small cell lung cancers |
| US8710020B2 (en) * | 2004-04-02 | 2014-04-29 | The University Of British Columbia | Clusterin antisense therapy for treatment of cancer |
| MX2010014228A (es) * | 2008-06-18 | 2011-03-29 | Abbott Laboratories Star | Metodos y productos de diagnostico del p/gf-1 acompañante. |
| JP2014520081A (ja) * | 2011-05-19 | 2014-08-21 | テバ ファーマシューティカル インダストリーズ リミティド | 非小細胞肺癌を処置するための方法 |
-
2013
- 2013-05-16 UY UY0001034812A patent/UY34812A/es not_active Application Discontinuation
- 2013-05-17 TW TW102117597A patent/TW201402132A/zh unknown
- 2013-05-17 CN CN201380030309.9A patent/CN104684564A/zh active Pending
- 2013-05-17 BR BR112014028787A patent/BR112014028787A2/pt not_active IP Right Cessation
- 2013-05-17 JP JP2015512895A patent/JP2015522542A/ja active Pending
- 2013-05-17 KR KR20147035652A patent/KR20150024843A/ko not_active Application Discontinuation
- 2013-05-17 WO PCT/US2013/041652 patent/WO2013173757A1/en active Application Filing
- 2013-05-17 CA CA2874092A patent/CA2874092A1/en not_active Abandoned
- 2013-05-17 US US13/896,737 patent/US20130310440A1/en not_active Abandoned
- 2013-05-17 IN IN10390DEN2014 patent/IN2014DN10390A/en unknown
- 2013-05-17 AU AU2013262589A patent/AU2013262589A1/en not_active Abandoned
- 2013-05-17 EA EA201492148A patent/EA201492148A1/ru unknown
- 2013-05-17 EP EP13791341.4A patent/EP2849761A1/en not_active Withdrawn
- 2013-05-17 AR ARP130101729A patent/AR091090A1/es unknown
- 2013-05-17 SG SG11201407649RA patent/SG11201407649RA/en unknown
-
2014
- 2014-11-02 IL IL235459A patent/IL235459A0/en unknown
- 2014-11-18 PH PH12014502569A patent/PH12014502569A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW201402132A (zh) | 2014-01-16 |
| PH12014502569A1 (en) | 2015-01-21 |
| WO2013173757A1 (en) | 2013-11-21 |
| SG11201407649RA (en) | 2014-12-30 |
| JP2015522542A (ja) | 2015-08-06 |
| CA2874092A1 (en) | 2013-11-21 |
| CN104684564A (zh) | 2015-06-03 |
| EP2849761A1 (en) | 2015-03-25 |
| BR112014028787A2 (pt) | 2017-06-27 |
| US20130310440A1 (en) | 2013-11-21 |
| AU2013262589A1 (en) | 2015-01-22 |
| EA201492148A1 (ru) | 2015-04-30 |
| IN2014DN10390A (es) | 2015-08-14 |
| UY34812A (es) | 2013-12-31 |
| WO2013173757A8 (en) | 2015-04-30 |
| IL235459A0 (en) | 2014-12-31 |
| KR20150024843A (ko) | 2015-03-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |