SG11201406343PA - Ketone bodies and ketone body esters for maintaining or improving muscle power output - Google Patents

Ketone bodies and ketone body esters for maintaining or improving muscle power output

Info

Publication number
SG11201406343PA
SG11201406343PA SG11201406343PA SG11201406343PA SG11201406343PA SG 11201406343P A SG11201406343P A SG 11201406343PA SG 11201406343P A SG11201406343P A SG 11201406343PA SG 11201406343P A SG11201406343P A SG 11201406343PA SG 11201406343P A SG11201406343P A SG 11201406343PA
Authority
SG
Singapore
Prior art keywords
ketone
maintaining
power output
muscle power
improving muscle
Prior art date
Application number
SG11201406343PA
Other languages
English (en)
Inventor
Kieran Clarke
Peter Cox
Original Assignee
Tdeltas Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tdeltas Ltd filed Critical Tdeltas Ltd
Publication of SG11201406343PA publication Critical patent/SG11201406343PA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225Polycarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06Anabolic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
SG11201406343PA 2012-04-05 2013-04-05 Ketone bodies and ketone body esters for maintaining or improving muscle power output SG11201406343PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1206192.5A GB201206192D0 (en) 2012-04-05 2012-04-05 Ketone bodies and ketone body esters and for maintaining or improving muscle power output
PCT/EP2013/057250 WO2013150153A1 (en) 2012-04-05 2013-04-05 Ketone bodies and ketone body esters for maintaining or improving muscle power output

Publications (1)

Publication Number Publication Date
SG11201406343PA true SG11201406343PA (en) 2014-11-27

Family

ID=46176983

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201406343PA SG11201406343PA (en) 2012-04-05 2013-04-05 Ketone bodies and ketone body esters for maintaining or improving muscle power output

Country Status (9)

Country Link
US (1) US20150164855A1 (enExample)
EP (1) EP2833882B1 (enExample)
JP (1) JP6241956B2 (enExample)
AU (1) AU2013244931B2 (enExample)
CA (1) CA2873092C (enExample)
ES (1) ES2748050T3 (enExample)
GB (1) GB201206192D0 (enExample)
SG (1) SG11201406343PA (enExample)
WO (1) WO2013150153A1 (enExample)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060280721A1 (en) 2003-06-03 2006-12-14 The Gov Of Usa Represented By Secretary Of Dpt Of Nutritional supplements and therapeutic compositions comprising (r)-3- hydroxybutyrate derivatives
DK2240017T3 (da) 2008-01-04 2019-06-17 Univ Oxford Innovation Ltd Ketonlegemer og ketonlegemsestere som blodlipid-sænkende midler
US8642654B2 (en) 2009-04-16 2014-02-04 Isis Innovation Limited Hydroxybutyrate ester and medical use thereof
GB201002983D0 (en) 2010-02-22 2010-04-07 Tdeltas Ltd Nutritinal composition
EP3659595A1 (en) 2012-11-05 2020-06-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Ketone bodies to protect tissues from damage by ionizing radiation
GB201304467D0 (en) 2013-03-12 2013-04-24 Tdeltas Ltd Compound for use in protecting skin
KR102265842B1 (ko) 2013-03-14 2021-06-15 옥스포드 유니버시티 이노베이션 리미티드 (r)­3­하이드록시부틸 (r)­3­하이드록시부티레이트를 생산하는 방법
MY180761A (en) 2013-03-19 2020-12-08 Univ South Florida Compositions and methods for producing elevated and sustained ketosis
GB201314127D0 (en) * 2013-08-07 2013-09-18 Tdeltas Ltd Ketone body and ketone body ester for reducing muscle breakdown
JP2015141458A (ja) * 2014-01-27 2015-08-03 株式会社タニタ ダイエット支援装置、方法、及びプログラム
EP3177284B1 (en) * 2014-07-21 2020-01-15 Oulun Yliopisto Oligomeric forms of 3-hydroxybutyrate
US10973786B2 (en) 2016-03-11 2021-04-13 Axcess Global Sciences, Llc R-beta-hydroxybutyrate, S-beta-hydroxybutyrate, and RS-beta-hydroxybutyrate mixed salt compositions
US10736861B2 (en) 2016-03-11 2020-08-11 Axcess Global Sciences, Llc Mixed salt compositions for producing elevated and sustained ketosis
US11103470B2 (en) 2017-11-22 2021-08-31 Axcess Global Sciences, Llc Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use
US10245242B1 (en) * 2017-11-22 2019-04-02 Axcess Global Sciences, Llc Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use
US10245243B1 (en) * 2017-12-19 2019-04-02 Axcess Global Sciences, Llc Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the S-enantiomer and methods of use
US11185518B2 (en) 2017-12-19 2021-11-30 Axcess Global Sciences, Llc S-beta-hydroxybutyrate compounds and compositions enriched with S-enantiomer
US10973792B2 (en) 2019-02-13 2021-04-13 Axcess Global Sciences, Llc Racemic beta-hydroxybutyrate mixed salt-acid compositions and methods of use
US11241403B2 (en) 2016-03-11 2022-02-08 Axcess Global Sciences, Llc Beta-hydroxybutyrate mixed salt compositions and methods of use
US20190091189A1 (en) * 2016-03-21 2019-03-28 Csilla Ari D'Agostino Administration of exogenous ketone to lower blood glucose
US10925843B2 (en) 2018-04-18 2021-02-23 Axcess Global Sciences, Llc Compositions and methods for keto stacking with beta-hydroxybutyrate and acetoacetate
US11202769B2 (en) 2017-11-22 2021-12-21 Axcess Global Sciences, Llc Ketone body esters of s-beta-hydroxybutyrate and/or s-1,3-butanediol for modifying metabolic function
US12109182B2 (en) 2016-04-19 2024-10-08 Axcess Global Sciences, Llc Administration of R-beta-hydroxybutyrate and related compounds in humans
US11806324B2 (en) 2018-04-18 2023-11-07 Axcess Global Sciences, Llc Beta-hydroxybutyric acid compositions and methods for oral delivery of ketone bodies
US11944598B2 (en) 2017-12-19 2024-04-02 Axcess Global Sciences, Llc Compositions containing s-beta-hydroxybutyrate or non-racemic mixtures enriched with the s-enatiomer
US12329734B2 (en) 2017-12-19 2025-06-17 Axcess Global Sciences, Llc Use of S-beta-hydroxybutyrate compounds for induction and maintenance of flow
US12496283B2 (en) 2016-04-19 2025-12-16 Axcess Global Sciences, Llc Administration of R-beta-hydroxybutyrate and related compounds in humans
US20180057846A1 (en) 2016-08-30 2018-03-01 KetoneAid Inc. Partially buffered free acid and/or ketone blend for rapid onset ketosis and metabolic therapy
FI3558280T3 (fi) 2016-12-21 2023-07-13 Univ Kinderspital Beider Basel Migreenin ennaltaehkäisy ja hoito
JP7174428B2 (ja) * 2016-12-23 2022-11-17 カトリーケ・ユニフェルシテイト・ルーヴァン 救命救急処置の処置における使用のための3-ヒドロキシブチレートの単独または併用
EP3601547A1 (en) 2017-03-31 2020-02-05 Genomatica, Inc. 3-hydroxybutyryl-coa dehydrogenase variants and methods of use
US20210101855A1 (en) 2017-03-31 2021-04-08 Genomatica, Inc. Process and systems for obtaining 1,3-butanediol from fermentation broths
KR102645531B1 (ko) 2017-03-31 2024-03-11 게노마티카 인코포레이티드 알데하이드 데하이드로게나제 변이체 및 사용 방법
US20190231742A1 (en) * 2017-04-20 2019-08-01 Theodore B. VANITALLIE Nutritional agents used to prevent and treat hypersensitivity and other allergic-type disorders
GB201710229D0 (en) * 2017-06-27 2017-08-09 Tdeltas Ltd Compounds for new use
US11760963B2 (en) 2017-08-23 2023-09-19 KetoneAid Inc. Ketogenic beer and alcoholic beverage mixture containing non-racemic ethyl 3-hydroxybutyrate and/or 1,3 butanediol
GB201715654D0 (en) 2017-09-27 2017-11-08 Tdeltas Ltd Method of treatment
US12090129B2 (en) 2017-11-22 2024-09-17 Axcess Global Sciences, Llc Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use
WO2019183564A1 (en) * 2018-03-23 2019-09-26 Concert Pharmaceuticals, Inc. DEUTERATED ANALOGS OF D-β-HYDROXYBUTYRIC ACID AND USES THEREOF
US11419836B2 (en) 2019-02-13 2022-08-23 Axcess Global Sciences, Llc Racemic and near racemic beta-hydroxybutyrate mixed salt-acid compositions
US11129802B2 (en) 2018-08-27 2021-09-28 Axcess Global Sciences, Llc Compositions and methods for delivering cannabidiol and ketone bodies
US11241401B2 (en) 2020-02-06 2022-02-08 Axcess Global Sciences, Llc Enantiomerically pure r-beta-hydroxybutyrate mixed salt-acid compositions
US10980772B2 (en) 2018-08-27 2021-04-20 Axcess Global Sciences, Llc Compositions and methods for delivering tetrahydrocannabinol and ketone bodies
GB2575623B (en) * 2018-06-04 2022-10-26 Tdeltas Ltd 3-hydroxybutyrate esters for treating cancer cachexia
EP3856896A1 (en) 2018-09-26 2021-08-04 Genomatica, Inc. Aldehyde dehydrogenase variants and methods of using same
GB2577723A (en) * 2018-10-04 2020-04-08 Tdeltas Ltd Compounds for new use
FI3880649T3 (fi) * 2019-01-17 2023-05-30 Ketolipix Therapeutics Gmbh Menetelmä hydroksikarboksyylihappojen polyolipohjaisten estereiden tuottamiseksi
US12091383B2 (en) * 2019-01-17 2024-09-17 Ketolipix Therapeutics Gmbh Method for producing lipids comprising structural units based on glycerides of hydroxycarboxylc acids
CN113574048B (zh) * 2019-01-17 2024-06-18 凯托利皮克斯治疗有限责任公司 生产任选的酰化羟基羧酸的多元醇基酯的方法
FI3880641T3 (fi) 2019-01-17 2023-06-02 Ketolipix Therapeutics Gmbh Menetelmä hydroksikarboksyylihappojen glyseridien tuottamiseksi
BR112021017954A2 (pt) * 2019-03-14 2021-11-16 Neuroenergy Ventures Inc Formulação de mascaramento de sabor para compostos de corpo cetônico
US12472200B2 (en) 2019-05-15 2025-11-18 Axcess Global Sciences, Llc Autobiotic compositions and method for promoting healthy gut microbiome
US20250197566A1 (en) * 2019-06-12 2025-06-19 Ioi Oleo Gmbh Process for preparing polyol-based esters of acyl-capped hydroxy carboxylic acids
WO2020249196A1 (de) * 2019-06-12 2020-12-17 Ioi Oleo Gmbh Verfahren zur herstellung von polyolbasierten estern, insbesondere polyglycerinestern, von hydroxycarbonsäuren
US11033553B2 (en) 2019-06-21 2021-06-15 Axcess Global Sciences, Llc Non-vasoconstricting energy-promoting compositions containing ketone bodies
US11969430B1 (en) 2023-03-10 2024-04-30 Axcess Global Sciences, Llc Compositions containing paraxanthine and beta-hydroxybutyrate or precursor for increasing neurological and physiological performance
US12167993B2 (en) 2019-06-21 2024-12-17 Axcess Global Sciences, Llc Non-vasoconstricting energy-promoting compositions containing ketone bodies
US11950616B2 (en) 2019-06-21 2024-04-09 Axcess Global Sciences, Llc Non-vasoconstricting energy-promoting compositions containing ketone bodies
EP4114203A1 (en) 2020-03-05 2023-01-11 VitaNav, Inc. COMPOSITION OF (D)-ß-HYDROXYBUTYRIC ACID, (D)-ß-HYDROXYVALERIC ACID, AND (D)-1,3 BUTANEDIOL AS A NUTRITIONAL SUPPLEMENT AND THERAPEUTIC AGENT
US12396974B2 (en) 2020-03-27 2025-08-26 KetoneAid Ketone ester as a therapeutic treatment of Covid-19 and related viral infections
JP7737231B2 (ja) * 2020-03-31 2025-09-10 大阪瓦斯株式会社 ジオール化合物およびその重合体ならびにそれらの製造方法
US12186297B2 (en) 2020-08-26 2025-01-07 Axcess Global Sciences, Llc Compositions and methods for increasing lean-to-fat mass ratio
CA3219283A1 (en) 2021-07-17 2023-01-26 Elena GROSS Combination of a ketone body or ketogenic compound with an analgesic or antioxidant
US20240336646A1 (en) * 2021-11-12 2024-10-10 Arxada Ag Polyol-Derived Compounds
US11807600B2 (en) 2021-11-12 2023-11-07 Samuel J. Rozzoni Synthesis of novel ketone body analogs for use as a nutritional supplement
GB202219317D0 (en) * 2022-12-20 2023-02-01 Amazentis Sa Methods for improving mitophagy in subjects

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995009144A1 (en) * 1993-09-30 1995-04-06 Eastman Chemical Company Nutritive water soluble glycerol esters of hydroxy butyric acid
JP4598203B2 (ja) 1995-12-01 2010-12-15 ビーティージー・インターナショナル・リミテッド 脳機能改善剤
WO2004105742A1 (en) * 2003-06-02 2004-12-09 Isis Innovation Limited Treatment of muscle fatigue
US20060280721A1 (en) * 2003-06-03 2006-12-14 The Gov Of Usa Represented By Secretary Of Dpt Of Nutritional supplements and therapeutic compositions comprising (r)-3- hydroxybutyrate derivatives
US7117715B2 (en) * 2004-07-09 2006-10-10 Owens-Brockway Glass Container Inc. Servo mechanism test stand
US7947736B2 (en) * 2004-07-16 2011-05-24 Btg International Limited Oligomeric compounds
US8642654B2 (en) * 2009-04-16 2014-02-04 Isis Innovation Limited Hydroxybutyrate ester and medical use thereof
NO2328858T3 (enExample) * 2008-08-21 2018-03-10
GB201002983D0 (en) * 2010-02-22 2010-04-07 Tdeltas Ltd Nutritinal composition

Also Published As

Publication number Publication date
EP2833882A1 (en) 2015-02-11
HK1206999A1 (en) 2016-01-22
AU2013244931B2 (en) 2018-01-18
JP2015514104A (ja) 2015-05-18
JP6241956B2 (ja) 2017-12-06
CA2873092A1 (en) 2013-10-10
CA2873092C (en) 2020-08-04
EP2833882B1 (en) 2019-07-24
ES2748050T3 (es) 2020-03-12
US20150164855A1 (en) 2015-06-18
GB201206192D0 (en) 2012-05-23
WO2013150153A1 (en) 2013-10-10
AU2013244931A1 (en) 2014-11-20

Similar Documents

Publication Publication Date Title
SG11201406343PA (en) Ketone bodies and ketone body esters for maintaining or improving muscle power output
GB2517088B (en) Ketone body and ketone body ester for reducing muscle breakdown
GB2500915B (en) Arrangement and method
IL225246A0 (en) Methods for speeding up the restoration of skin normality and for treatment of impetigo
GB201215962D0 (en) Power tailgate system and method
IL233674A0 (en) Preparations and methods for using phorbol esters for stroke treatment
HUE042637T2 (hu) Laminátumok és azok elõállítására szolgáló módszerek
GB201218862D0 (en) Bicyclic heterocycle compounds and their uses in therapy
AP2014008172A0 (en) Nanocomposite and method of making the same
GB201218850D0 (en) Bicyclic heterocycle compounds and their uses in therapy
EP2631068A4 (en) LAMINATED BODY AND MANUFACTURING METHOD THEREOF
GB201218864D0 (en) Bicyclic heterocycle compounds and their uses in therapy
GB2508041B (en) Rack and power control method thereof
GB201218831D0 (en) Permenter and the method of fermentation
EP2857289A4 (en) STRUCTURAL BODY OF A SHOCK CABINET AND MANUFACTURING METHOD FOR STRUCTURAL BODY OF A SHOCK CABINET
PL2919736T3 (pl) Wyroby chłonne obejmujące laminat i sposoby ich wytwarzania
EP2852571A4 (en) COMPOSITIONS AND METHOD FOR THE TREATMENT OF MUCOSITIS
IL238274A0 (en) Methods and preparations for local increase of body fat
AU343512S (en) Human model
GB2510238B8 (en) Power converter and its control method
EP2849712A4 (en) METHOD AND DEVICES FOR PROVIDING MECHANICAL STIMULATION TO A BODY
ZA201405932B (en) Energy plant and parts of an energy plant
SG11201503663SA (en) Settling tank and method of operating the same
EP2931140A4 (en) Tissue repair equipment and methods
ZA201500547B (en) Alpha-1-microglobulin for use in the treatment of mitochondria-related diseases