SG11201406105UA - Immunofluorescence and fluorescent-based nucleic acid analysis on a single sample - Google Patents

Immunofluorescence and fluorescent-based nucleic acid analysis on a single sample

Info

Publication number
SG11201406105UA
SG11201406105UA SG11201406105UA SG11201406105UA SG11201406105UA SG 11201406105U A SG11201406105U A SG 11201406105UA SG 11201406105U A SG11201406105U A SG 11201406105UA SG 11201406105U A SG11201406105U A SG 11201406105UA SG 11201406105U A SG11201406105U A SG 11201406105UA
Authority
SG
Singapore
Prior art keywords
immunofluorescence
fluorescent
nucleic acid
acid analysis
single sample
Prior art date
Application number
SG11201406105UA
Other languages
English (en)
Inventor
Antti E Seppo
Fiona Ginty
Kevin B Kenny
David Lavan Henderson
Michael J Gerdes
Moreno Adriana I Larriera
Xiaofeng Liu
Alex D Corwin
Stephen E Zingelewicz
Thomas Ha
Natalie R Jun
Ainura Kyshtoobayeve
Denise A Hollman-Hewgley
Ying Li
Original Assignee
Clarient Diagnostic Services Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clarient Diagnostic Services Inc filed Critical Clarient Diagnostic Services Inc
Publication of SG11201406105UA publication Critical patent/SG11201406105UA/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57423—Specifically defined cancers of lung
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57415—Specifically defined cancers of breast
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
SG11201406105UA 2012-03-30 2013-03-21 Immunofluorescence and fluorescent-based nucleic acid analysis on a single sample SG11201406105UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261618132P 2012-03-30 2012-03-30
PCT/US2013/033249 WO2013148448A1 (en) 2012-03-30 2013-03-21 Immunoflu0rescence and fluorescent-based nucleic acid analysis on a single sample

Publications (1)

Publication Number Publication Date
SG11201406105UA true SG11201406105UA (en) 2014-10-30

Family

ID=48050953

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201406105UA SG11201406105UA (en) 2012-03-30 2013-03-21 Immunofluorescence and fluorescent-based nucleic acid analysis on a single sample

Country Status (12)

Country Link
US (1) US20150065371A1 (ru)
EP (1) EP2831591B1 (ru)
JP (1) JP6225163B2 (ru)
KR (1) KR20140142715A (ru)
CN (1) CN104520713A (ru)
AU (1) AU2013240127B2 (ru)
CA (1) CA2867508C (ru)
IN (1) IN2014DN07531A (ru)
NZ (1) NZ630091A (ru)
RU (1) RU2014137129A (ru)
SG (1) SG11201406105UA (ru)
WO (1) WO2013148448A1 (ru)

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WO2015124737A1 (en) 2014-02-24 2015-08-27 Ventana Medical Systems, Inc. Methods, kits, and systems for scoring the immune response to cancer by simultaneous detection of cd3, cd8, cd20 and foxp3
CN104980558B (zh) * 2014-04-01 2019-01-01 中国移动通信集团公司 一种信息处理的方法、装置、手机宠物客户端及移动终端
US20150286887A1 (en) * 2014-04-07 2015-10-08 Massachusetts Institute Of Technology Use of Microparticle Additives to Simultaneously Enable Artifact-Free Image Registration, Auto-Focusing, and Chromatic Aberration Correction in Microscopy
CA2995719A1 (en) * 2014-08-18 2016-02-25 Viewsiq Inc. System and method for embedded images in large field-of-view microscopic scans
CN107407638B (zh) 2014-12-03 2021-01-12 伊索普莱西斯公司 细胞分泌特征的分析和筛选
US11353448B2 (en) 2015-02-13 2022-06-07 California Institute Of Technology Methods and compositions for quantifying metabolites and proteins from single cells
US10706536B2 (en) * 2015-07-20 2020-07-07 Min Xu Photon structure and chemometrics pathologic system
WO2017110974A1 (ja) 2015-12-24 2017-06-29 コニカミノルタ株式会社 画像処理装置及びプログラム
CN107419001A (zh) * 2016-05-23 2017-12-01 益善生物技术股份有限公司 Brca1、pten基因异常检测试剂盒及检测方法
JP6231709B1 (ja) * 2016-05-31 2017-11-15 シスメックス株式会社 蛍光画像分析装置および分析方法
EP3469548B1 (en) * 2016-06-10 2020-05-13 H. Hoffnabb-La Roche Ag System for bright field image simulation
CN106290878A (zh) * 2016-09-10 2017-01-04 天津大学 基于量子点的胰腺癌肿瘤标志物ca242免疫层析试纸条的制备方法
CA3034924A1 (en) * 2016-09-26 2018-03-29 Cellular Research, Inc. Measurement of protein expression using reagents with barcoded oligonucleotide sequences
WO2018089910A2 (en) 2016-11-11 2018-05-17 IsoPlexis Corporation Compositions and methods for the simultaneous genomic, transcriptomic and proteomic analysis of single cells
WO2018098372A1 (en) 2016-11-22 2018-05-31 IsoPlexis Corporation Systems, devices and methods for cell capture and methods of manufacture thereof
JP7116175B2 (ja) * 2018-08-22 2022-08-09 オリンパス株式会社 画像処理装置、撮像システム、画像処理装置の作動方法、及び画像処理装置の作動プログラム
US10921223B2 (en) * 2018-10-12 2021-02-16 Shenzhen Prs Limited Process record slide for staining and method of using the same
CN110498858B (zh) * 2019-07-26 2024-01-23 深圳市达科为生物工程有限公司 一种动态检测单细胞外泌蛋白分泌情况的方法
WO2021127019A1 (en) 2019-12-17 2021-06-24 Applied Materials, Inc. System and method for acquisition and processing of multiplexed fluorescence in-situ hybridization images
US20220018778A1 (en) * 2020-07-20 2022-01-20 Akoya Biosciences, Inc. Processing and imaging tissue samples
JP7492650B2 (ja) 2020-08-13 2024-05-29 ベンタナ メディカル システムズ， インコーポレイテッド 多重免疫蛍光染色組織のデジタル画像における壊死領域の自動識別
CN112415198B (zh) * 2020-11-20 2022-11-11 四川大学华西医院 Gp1bb检测试剂在制备肺癌筛查试剂盒中的用途
CN113310963B (zh) * 2021-05-31 2023-12-01 四川大学华西医院 一种改进的中性粒细胞NETs免疫荧光检测方法
IL312540A (en) 2021-11-16 2024-07-01 Sotio Biotech Inc Treatment of patients with myxoid/round cell liposarcoma
WO2023147139A1 (en) * 2022-01-28 2023-08-03 University Of Southern California Identifying non-disease patients using a disease related assay and analysis in the liquid biopsy
WO2023147133A1 (en) * 2022-01-28 2023-08-03 University Of Southern California Liquid biopsy analytes to define cancer stages

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Also Published As

Publication number Publication date
EP2831591B1 (en) 2019-05-08
JP6225163B2 (ja) 2017-11-01
AU2013240127A1 (en) 2014-10-02
KR20140142715A (ko) 2014-12-12
CA2867508C (en) 2021-05-18
WO2013148448A1 (en) 2013-10-03
US20150065371A1 (en) 2015-03-05
AU2013240127B2 (en) 2018-07-12
JP2015514212A (ja) 2015-05-18
CA2867508A1 (en) 2013-10-03
RU2014137129A (ru) 2016-05-27
EP2831591A1 (en) 2015-02-04
IN2014DN07531A (ru) 2015-04-24
NZ630091A (en) 2016-03-31
CN104520713A (zh) 2015-04-15

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