SG10202103618XA - Binding molecules directed against influenza hemagglutinin and uses thereof - Google Patents
Binding molecules directed against influenza hemagglutinin and uses thereofInfo
- Publication number
- SG10202103618XA SG10202103618XA SG10202103618XA SG10202103618XA SG10202103618XA SG 10202103618X A SG10202103618X A SG 10202103618XA SG 10202103618X A SG10202103618X A SG 10202103618XA SG 10202103618X A SG10202103618X A SG 10202103618XA SG 10202103618X A SG10202103618X A SG 10202103618XA
- Authority
- SG
- Singapore
- Prior art keywords
- directed against
- binding molecules
- influenza hemagglutinin
- against influenza
- molecules directed
- Prior art date
Links
- 101710154606 Hemagglutinin Proteins 0.000 title 1
- 101710093908 Outer capsid protein VP4 Proteins 0.000 title 1
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 title 1
- 101710176177 Protein A56 Proteins 0.000 title 1
- 239000000185 hemagglutinin Substances 0.000 title 1
- 206010022000 influenza Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1018—Orthomyxoviridae, e.g. influenza virus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/22—Immunoglobulins specific features characterized by taxonomic origin from camelids, e.g. camel, llama or dromedary
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/526—CH3 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/64—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a combination of variable region and constant region components
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/11—Orthomyxoviridae, e.g. influenza virus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/26—Infectious diseases, e.g. generalised sepsis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP15153957 | 2015-02-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10202103618XA true SG10202103618XA (en) | 2021-05-28 |
Family
ID=52484335
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10202103618XA SG10202103618XA (en) | 2015-02-05 | 2016-02-05 | Binding molecules directed against influenza hemagglutinin and uses thereof |
SG11201705614QA SG11201705614QA (en) | 2015-02-05 | 2016-02-05 | Binding molecules directed against influenza hemagglutinin and uses thereof |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201705614QA SG11201705614QA (en) | 2015-02-05 | 2016-02-05 | Binding molecules directed against influenza hemagglutinin and uses thereof |
Country Status (17)
Country | Link |
---|---|
US (3) | US10370435B2 (zh) |
EP (1) | EP3253411A1 (zh) |
JP (2) | JP6772157B2 (zh) |
KR (1) | KR20170107562A (zh) |
CN (1) | CN107207611B (zh) |
AU (1) | AU2016214304B2 (zh) |
BR (1) | BR112017016417A2 (zh) |
CA (1) | CA2975655C (zh) |
EA (1) | EA038407B1 (zh) |
HK (1) | HK1243925A1 (zh) |
IL (1) | IL253653B (zh) |
MX (1) | MX2017010009A (zh) |
MY (1) | MY186585A (zh) |
PH (1) | PH12017501216A1 (zh) |
SG (2) | SG10202103618XA (zh) |
WO (1) | WO2016124768A1 (zh) |
ZA (1) | ZA201705300B (zh) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10053513B2 (en) | 2009-11-30 | 2018-08-21 | Janssen Biotech, Inc. | Antibody Fc mutants with ablated effector functions |
SG10202103618XA (en) | 2015-02-05 | 2021-05-28 | Janssen Vaccines & Prevention Bv | Binding molecules directed against influenza hemagglutinin and uses thereof |
CA2985081A1 (en) | 2015-05-13 | 2016-12-15 | The Trustees Of The University Of Pennsylvania | Aav-mediated expression of anti-influenza antibodies and methods of use thereof |
MX2017014908A (es) | 2015-05-21 | 2018-08-15 | Harpoon Therapeutics Inc | Proteinas de union triespecificas y metodos de uso. |
US10100106B2 (en) | 2016-05-20 | 2018-10-16 | Harpoon Therapeutics, Inc. | Single domain serum albumin binding protein |
US11623958B2 (en) | 2016-05-20 | 2023-04-11 | Harpoon Therapeutics, Inc. | Single chain variable fragment CD3 binding proteins |
WO2018078008A1 (en) | 2016-10-27 | 2018-05-03 | Janssen Vaccines & Prevention B.V. | Influenza virus neutralizing compounds |
US10844134B2 (en) | 2016-11-23 | 2020-11-24 | Harpoon Therapeutics, Inc. | PSMA targeting trispecific proteins and methods of use |
CA3044659A1 (en) | 2016-11-23 | 2018-05-31 | Harpoon Therapeutics, Inc. | Prostate specific membrane antigen binding protein |
CN106822887A (zh) * | 2017-01-26 | 2017-06-13 | 中国科学院微生物研究所 | 一种流感病毒四价亚单位疫苗及其应用 |
CN110573523A (zh) | 2017-02-28 | 2019-12-13 | 宾夕法尼亚州大学信托人 | 基于aav载体的流感疫苗 |
JOP20190200A1 (ar) | 2017-02-28 | 2019-08-27 | Univ Pennsylvania | تركيبات نافعة في معالجة ضمور العضل النخاعي |
US11535668B2 (en) | 2017-02-28 | 2022-12-27 | Harpoon Therapeutics, Inc. | Inducible monovalent antigen binding protein |
SI3589730T1 (sl) | 2017-02-28 | 2024-04-30 | The Trustees Of The University Of Pennsylvania | Adeno-povezan virus (AAV) clade F vektor in njihova uporaba |
JP7090347B2 (ja) | 2017-05-12 | 2022-06-24 | ハープーン セラピューティクス,インク. | メソテリン結合タンパク質 |
KR20200026810A (ko) | 2017-05-12 | 2020-03-11 | 하푼 테라퓨틱스, 인크. | Msln 표적화 삼중 특이적 단백질 및 사용 방법 |
BR112020007249B1 (pt) | 2017-10-13 | 2022-11-22 | Harpoon Therapeutics, Inc | Roteína de ligação a antígeno de maturação de célula b, proteína de ligação multiespecífica e uso das referidas proteínas |
JP7084990B2 (ja) | 2017-10-13 | 2022-06-15 | ハープーン セラピューティクス,インク. | 三重特異性タンパク質と使用方法 |
JP7162190B2 (ja) * | 2018-07-17 | 2022-10-28 | パナソニックIpマネジメント株式会社 | インフルエンザウィルス核内蛋白質に結合する抗体、複合体、それを用いた検出装置及び検出方法 |
WO2020061482A1 (en) * | 2018-09-21 | 2020-03-26 | Harpoon Therapeutics, Inc. | Egfr binding proteins and methods of use |
WO2020069028A1 (en) | 2018-09-25 | 2020-04-02 | Harpoon Therapeutics, Inc. | Dll3 binding proteins and methods of use |
CA3170833A1 (en) | 2020-02-21 | 2021-08-26 | Harpoon Therapeutics, Inc. | Flt3 binding proteins and methods of use |
CA3197537A1 (en) * | 2020-11-23 | 2022-05-27 | Davide Corti | Antibodies against influenza a viruses |
US20240166739A1 (en) * | 2021-03-31 | 2024-05-23 | Kisoji Biotechnology Inc. | Binding agents targeting tumors and/or immune cells |
WO2024073435A2 (en) * | 2022-09-27 | 2024-04-04 | Anwita Biosciences, Inc. | Anti-lag-3/il-2 fusion proteins, encoding polynucleotides, pharmaceutical compositions, and therapeutic applications |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ207394A (en) | 1983-03-08 | 1987-03-06 | Commw Serum Lab Commission | Detecting or determining sequence of amino acids |
NL9101953A (nl) | 1991-11-21 | 1993-06-16 | Seed Capital Investments | Testinrichting omvattende een plaat met een veelvoud van putjes met een bijbehorende doseerinrichting, alsmede een kit die deze inrichtingen omvat en toepassing van de inrichtingen. |
JP4210036B2 (ja) | 1999-04-15 | 2009-01-14 | クルセル ホランド ベー ヴェー | ヒト細胞における組み換え蛋白質の生産 |
GB0522460D0 (en) | 2005-11-03 | 2005-12-14 | Prendergast Patrick T | Composition and method for the treatment of avian influenza |
EP2059532B1 (en) | 2006-09-07 | 2012-12-26 | Crucell Holland B.V. | Human binding molecules capable of neutralizing influenza virus h5n1 and uses thereof |
EP2274334A2 (en) * | 2008-03-28 | 2011-01-19 | Sea Lane Biotechnologies,llc. | Neutralizing molecules to viral antigens |
JP5809557B2 (ja) * | 2008-06-05 | 2015-11-11 | アブリンクス エン.ヴェー. | ウイルスのエンベロープタンパク質に指向性を有するアミノ酸配列、及びウイルス疾患の治療のためのこれを含むポリペプチド |
US8871207B2 (en) | 2008-07-25 | 2014-10-28 | Humabs, LLC | Neutralizing anti-influenza A virus antibodies and uses thereof |
US8734803B2 (en) * | 2008-09-28 | 2014-05-27 | Ibio Inc. | Humanized neuraminidase antibody and methods of use thereof |
US8563305B2 (en) | 2009-04-30 | 2013-10-22 | Oklahoma Medical Research Foundation | Rapid generation of antibodies |
CN102276719B (zh) * | 2010-06-09 | 2014-12-24 | 中国科学院生物物理研究所 | 禽流感病毒单域抗体、五聚抗体及其制备和应用 |
CN102023212B (zh) | 2010-09-28 | 2014-04-02 | 汕头大学医学院 | 一种流感病毒神经氨酸酶抗体的快速检测方法 |
EP2731967B1 (en) * | 2011-07-14 | 2016-10-12 | Janssen Vaccines & Prevention B.V. | Human binding molecules capable of neutralizing influenza a viruses of phylogenetic group 1 and phylogenetic group 2 and influenza b viruses |
EP3812397A1 (en) * | 2011-07-18 | 2021-04-28 | Institute for Research in Biomedicine | Neutralizing anti-influenza a virus antibodies and uses thereof |
GB201115214D0 (en) | 2011-09-02 | 2011-10-19 | Health Prot Agency | Influenza virus antibody compositions |
KR102050615B1 (ko) | 2012-03-08 | 2019-11-29 | 얀센 백신스 앤드 프리벤션 비.브이. | 인플루엔자 b 바이러스들에 결합하고 중화할 수 있는 인간 결합 분자 및 그 용도 |
US9969794B2 (en) | 2012-05-10 | 2018-05-15 | Visterra, Inc. | HA binding agents |
WO2013169377A1 (en) | 2012-05-10 | 2013-11-14 | Massachusetts Institute Of Technology | Agents for influenza neutralization |
WO2014161483A1 (zh) * | 2013-04-02 | 2014-10-09 | 厦门大学 | 识别流感病毒血凝素蛋白ha1结构域的广谱单克隆抗体 |
SG10202103618XA (en) * | 2015-02-05 | 2021-05-28 | Janssen Vaccines & Prevention Bv | Binding molecules directed against influenza hemagglutinin and uses thereof |
-
2016
- 2016-02-05 SG SG10202103618XA patent/SG10202103618XA/en unknown
- 2016-02-05 KR KR1020177024174A patent/KR20170107562A/ko not_active Application Discontinuation
- 2016-02-05 BR BR112017016417-5A patent/BR112017016417A2/pt active Search and Examination
- 2016-02-05 AU AU2016214304A patent/AU2016214304B2/en active Active
- 2016-02-05 SG SG11201705614QA patent/SG11201705614QA/en unknown
- 2016-02-05 CN CN201680008842.9A patent/CN107207611B/zh active Active
- 2016-02-05 WO PCT/EP2016/052556 patent/WO2016124768A1/en active Application Filing
- 2016-02-05 MX MX2017010009A patent/MX2017010009A/es unknown
- 2016-02-05 MY MYPI2017702861A patent/MY186585A/en unknown
- 2016-02-05 EP EP16703151.7A patent/EP3253411A1/en not_active Ceased
- 2016-02-05 US US15/548,843 patent/US10370435B2/en active Active
- 2016-02-05 JP JP2017541117A patent/JP6772157B2/ja active Active
- 2016-02-05 CA CA2975655A patent/CA2975655C/en active Active
- 2016-02-05 EA EA201791735A patent/EA038407B1/ru unknown
-
2017
- 2017-06-29 PH PH12017501216A patent/PH12017501216A1/en unknown
- 2017-07-25 IL IL253653A patent/IL253653B/en unknown
- 2017-08-04 ZA ZA2017/05300A patent/ZA201705300B/en unknown
-
2018
- 2018-03-12 HK HK18103393.7A patent/HK1243925A1/zh unknown
-
2019
- 2019-06-27 US US16/455,151 patent/US10703804B2/en active Active
-
2020
- 2020-06-05 JP JP2020098605A patent/JP2020171288A/ja active Pending
- 2020-06-05 US US16/946,092 patent/US11136379B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
JP6772157B2 (ja) | 2020-10-21 |
MX2017010009A (es) | 2017-10-24 |
HK1243925A1 (zh) | 2018-07-27 |
EP3253411A1 (en) | 2017-12-13 |
ZA201705300B (en) | 2021-05-26 |
AU2016214304B2 (en) | 2021-11-11 |
JP2020171288A (ja) | 2020-10-22 |
PH12017501216A1 (en) | 2018-01-15 |
US20180016323A1 (en) | 2018-01-18 |
BR112017016417A2 (pt) | 2018-03-27 |
KR20170107562A (ko) | 2017-09-25 |
IL253653B (en) | 2021-10-31 |
SG11201705614QA (en) | 2017-08-30 |
WO2016124768A1 (en) | 2016-08-11 |
MY186585A (en) | 2021-07-28 |
AU2016214304A1 (en) | 2017-07-20 |
CN107207611B (zh) | 2021-11-09 |
US10703804B2 (en) | 2020-07-07 |
US11136379B2 (en) | 2021-10-05 |
US20200299364A1 (en) | 2020-09-24 |
US20190359693A1 (en) | 2019-11-28 |
CA2975655A1 (en) | 2016-08-11 |
EA201791735A1 (ru) | 2017-11-30 |
EA038407B1 (ru) | 2021-08-24 |
JP2018505677A (ja) | 2018-03-01 |
CN107207611A (zh) | 2017-09-26 |
US10370435B2 (en) | 2019-08-06 |
CA2975655C (en) | 2023-09-19 |
IL253653A0 (en) | 2017-09-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1243925A1 (zh) | 針對流感血球凝集素的結合分子及其用途 | |
EP3331549A4 (en) | Improved microbe-binding molecules and uses thereof | |
IL251891A0 (en) | CD73-specific binding molecules and uses thereof | |
GB201615617D0 (en) | Small molecules | |
GB201521858D0 (en) | Small molecules | |
IL251512A0 (en) | Mist sprayer and its uses | |
HK1248721A1 (zh) | 抗體分子及其用途 | |
HK1253092A1 (zh) | 中和抗流感結合分子及其用途 | |
HK1252026A1 (zh) | 藥物組合及其應用 | |
HK1258038A1 (zh) | 索拉貝隆兩性離子及其應用 | |
HK1247122A1 (zh) | 組合及其用途 | |
IL254241A0 (en) | Etv2 and its uses | |
IL264473A (en) | GPR156 variants and their uses | |
IL255024A0 (en) | Hydroxamic acids and their uses | |
GB201404438D0 (en) | Polyamine compounds and uses thereof |