SG10202011017RA - Filovirus consensus antigens, nucleic acid constructs and vacciens made therefrom, and methods of using same - Google Patents
Filovirus consensus antigens, nucleic acid constructs and vacciens made therefrom, and methods of using sameInfo
- Publication number
- SG10202011017RA SG10202011017RA SG10202011017RA SG10202011017RA SG10202011017RA SG 10202011017R A SG10202011017R A SG 10202011017RA SG 10202011017R A SG10202011017R A SG 10202011017RA SG 10202011017R A SG10202011017R A SG 10202011017RA SG 10202011017R A SG10202011017R A SG 10202011017RA
- Authority
- SG
- Singapore
- Prior art keywords
- vacciens
- methods
- nucleic acid
- same
- acid constructs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5434—IL-12
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5443—IL-15
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A61K2039/55527—Interleukins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A61K2039/55527—Interleukins
- A61K2039/55538—IL-12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/14011—Filoviridae
- C12N2760/14111—Ebolavirus, e.g. Zaire ebolavirus
- C12N2760/14122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/14011—Filoviridae
- C12N2760/14111—Ebolavirus, e.g. Zaire ebolavirus
- C12N2760/14134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662332372P | 2016-05-05 | 2016-05-05 | |
US201662402519P | 2016-09-30 | 2016-09-30 | |
US201762483979P | 2017-04-11 | 2017-04-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10202011017RA true SG10202011017RA (en) | 2020-12-30 |
Family
ID=60203604
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10202011017RA SG10202011017RA (en) | 2016-05-05 | 2017-05-05 | Filovirus consensus antigens, nucleic acid constructs and vacciens made therefrom, and methods of using same |
SG11201809780WA SG11201809780WA (en) | 2016-05-05 | 2017-05-05 | Filovirus consensus antigens, nucleic acid constructs and vacciens made therefrom, and methods of using same |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201809780WA SG11201809780WA (en) | 2016-05-05 | 2017-05-05 | Filovirus consensus antigens, nucleic acid constructs and vacciens made therefrom, and methods of using same |
Country Status (10)
Country | Link |
---|---|
US (2) | US11091518B2 (pt) |
EP (1) | EP3452068A4 (pt) |
JP (2) | JP7029756B2 (pt) |
CN (2) | CN117887735A (pt) |
AU (2) | AU2017261306B2 (pt) |
BR (1) | BR112018072719A2 (pt) |
CA (1) | CA3023098A1 (pt) |
MX (2) | MX2018013524A (pt) |
SG (2) | SG10202011017RA (pt) |
WO (1) | WO2017192947A1 (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG10202011017RA (en) * | 2016-05-05 | 2020-12-30 | Univ Pennsylvania | Filovirus consensus antigens, nucleic acid constructs and vacciens made therefrom, and methods of using same |
EP3548054A4 (en) * | 2016-12-02 | 2020-12-02 | The Trustees of the University of Pennsylvania | ANTI-DNA ANTIBODY CONSTRUCTIONS FOR USE AGAINST EBOLA VIRUS |
CN110655572B (zh) * | 2019-10-11 | 2022-08-16 | 中国科学院广州生物医药与健康研究院 | 一种抗丝状病毒gp蛋白的单克隆抗体及其应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8298820B2 (en) | 2010-01-26 | 2012-10-30 | The Trustees Of The University Of Pennsylvania | Influenza nucleic acid molecules and vaccines made therefrom |
KR20220012403A (ko) | 2012-04-12 | 2022-02-03 | 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 | 필로바이러스 공통 항원, 이로부터 제조된 핵산 구조체 및 백신, 및 이를 사용하는 방법 |
JP6817062B2 (ja) * | 2013-03-15 | 2021-01-20 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | 蹄疫ウイルス(fmdv)コンセンサスタンパク質、そのコード配列、およびそれから作成されるワクチン |
JP6462861B2 (ja) * | 2014-09-03 | 2019-01-30 | バヴァリアン ノルディック エー/エス | フィロウイルス感染に対する防御免疫の誘導を目的とする方法及び組成物 |
WO2016054003A1 (en) * | 2014-10-01 | 2016-04-07 | The Trustees Of The University Of Pennsylvania | Vaccines having an antigen and interleukin-21 as an adjuvant |
SG10202011017RA (en) * | 2016-05-05 | 2020-12-30 | Univ Pennsylvania | Filovirus consensus antigens, nucleic acid constructs and vacciens made therefrom, and methods of using same |
-
2017
- 2017-05-05 SG SG10202011017RA patent/SG10202011017RA/en unknown
- 2017-05-05 JP JP2019510571A patent/JP7029756B2/ja active Active
- 2017-05-05 EP EP17793414.8A patent/EP3452068A4/en active Pending
- 2017-05-05 CN CN202410055051.8A patent/CN117887735A/zh active Pending
- 2017-05-05 US US16/098,912 patent/US11091518B2/en active Active
- 2017-05-05 AU AU2017261306A patent/AU2017261306B2/en active Active
- 2017-05-05 SG SG11201809780WA patent/SG11201809780WA/en unknown
- 2017-05-05 MX MX2018013524A patent/MX2018013524A/es unknown
- 2017-05-05 CN CN201780042299.9A patent/CN110072536B/zh active Active
- 2017-05-05 CA CA3023098A patent/CA3023098A1/en active Pending
- 2017-05-05 WO PCT/US2017/031215 patent/WO2017192947A1/en unknown
- 2017-05-05 BR BR112018072719-9A patent/BR112018072719A2/pt unknown
-
2018
- 2018-11-05 MX MX2023003934A patent/MX2023003934A/es unknown
-
2021
- 2021-08-17 US US17/404,143 patent/US20210388033A1/en active Pending
-
2022
- 2022-02-10 JP JP2022019743A patent/JP2022078067A/ja active Pending
-
2024
- 2024-05-27 AU AU2024203524A patent/AU2024203524A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
CA3023098A1 (en) | 2017-11-09 |
AU2024203524A1 (en) | 2024-06-20 |
US20210388033A1 (en) | 2021-12-16 |
SG11201809780WA (en) | 2018-12-28 |
KR20190037200A (ko) | 2019-04-05 |
MX2018013524A (es) | 2019-06-10 |
EP3452068A1 (en) | 2019-03-13 |
BR112018072719A2 (pt) | 2019-02-19 |
US20190153040A1 (en) | 2019-05-23 |
CN110072536B (zh) | 2024-02-02 |
CN117887735A (zh) | 2024-04-16 |
US11091518B2 (en) | 2021-08-17 |
WO2017192947A1 (en) | 2017-11-09 |
JP7029756B2 (ja) | 2022-03-04 |
AU2017261306B2 (en) | 2024-02-29 |
CN110072536A (zh) | 2019-07-30 |
EP3452068A4 (en) | 2020-01-22 |
AU2017261306A1 (en) | 2018-12-20 |
MX2023003934A (es) | 2023-04-26 |
JP2022078067A (ja) | 2022-05-24 |
JP2019516400A (ja) | 2019-06-20 |
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