SG10201913570XA - Artificial match-type mirna for controlling gene expression and use therefor - Google Patents

Artificial match-type mirna for controlling gene expression and use therefor

Info

Publication number
SG10201913570XA
SG10201913570XA SG10201913570XA SG10201913570XA SG10201913570XA SG 10201913570X A SG10201913570X A SG 10201913570XA SG 10201913570X A SG10201913570X A SG 10201913570XA SG 10201913570X A SG10201913570X A SG 10201913570XA SG 10201913570X A SG10201913570X A SG 10201913570XA
Authority
SG
Singapore
Prior art keywords
gene expression
controlling gene
use therefor
type mirna
artificial match
Prior art date
Application number
SG10201913570XA
Inventor
Masahiko Kuroda
Shinichiro Ohno
Eriko Aoki
Yasuhiko Yoshida
Shiori Kato
Tadaaki Ohgi
Original Assignee
Bonac Corp
Univ Tokyo Medical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bonac Corp, Univ Tokyo Medical filed Critical Bonac Corp
Publication of SG10201913570XA publication Critical patent/SG10201913570XA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.
    • C12N2310/141—MicroRNAs, miRNAs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/31—Chemical structure of the backbone
    • C12N2310/318—Chemical structure of the backbone where the PO2 is completely replaced, e.g. MMI or formacetal
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/50—Physical structure
    • C12N2310/53—Physical structure partially self-complementary or closed
    • C12N2310/531—Stem-loop; Hairpin
SG10201913570XA 2013-12-27 2014-12-27 Artificial match-type mirna for controlling gene expression and use therefor SG10201913570XA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2013273033 2013-12-27

Publications (1)

Publication Number Publication Date
SG10201913570XA true SG10201913570XA (en) 2020-03-30

Family

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Family Applications (3)

Application Number Title Priority Date Filing Date
SG10201913570XA SG10201913570XA (en) 2013-12-27 2014-12-27 Artificial match-type mirna for controlling gene expression and use therefor
SG11201605247XA SG11201605247XA (en) 2013-12-27 2014-12-27 Artificial match-type mirna for controlling gene expression and use therefor
SG10201805087VA SG10201805087VA (en) 2013-12-27 2014-12-27 Artificial match-type mirna for controlling gene expression and use therefor

Family Applications After (2)

Application Number Title Priority Date Filing Date
SG11201605247XA SG11201605247XA (en) 2013-12-27 2014-12-27 Artificial match-type mirna for controlling gene expression and use therefor
SG10201805087VA SG10201805087VA (en) 2013-12-27 2014-12-27 Artificial match-type mirna for controlling gene expression and use therefor

Country Status (13)

Country Link
US (1) US10934542B2 (en)
EP (1) EP3088525A4 (en)
JP (2) JP6425142B2 (en)
KR (1) KR102357337B1 (en)
CN (2) CN106068324B (en)
AU (1) AU2014370829B2 (en)
BR (1) BR112016014986A2 (en)
CA (1) CA2935022A1 (en)
IL (2) IL246395B (en)
MX (1) MX2016008518A (en)
RU (1) RU2697094C2 (en)
SG (3) SG10201913570XA (en)
WO (1) WO2015099187A1 (en)

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Publication number Publication date
EP3088525A4 (en) 2017-08-09
IL271715B (en) 2022-03-01
SG11201605247XA (en) 2016-08-30
US20160319282A1 (en) 2016-11-03
AU2014370829A1 (en) 2016-08-11
CN112646812A (en) 2021-04-13
JP2018145199A (en) 2018-09-20
JP6653889B2 (en) 2020-02-26
US10934542B2 (en) 2021-03-02
CN106068324B (en) 2020-12-29
CN106068324A (en) 2016-11-02
JPWO2015099187A1 (en) 2017-03-23
MX2016008518A (en) 2017-01-26
KR20160121510A (en) 2016-10-19
WO2015099187A1 (en) 2015-07-02
AU2014370829B2 (en) 2021-03-11
SG10201805087VA (en) 2018-07-30
RU2016130611A3 (en) 2018-08-27
RU2697094C2 (en) 2019-08-12
RU2016130611A (en) 2018-01-31
IL246395B (en) 2020-01-30
CA2935022A1 (en) 2015-07-02
EP3088525A1 (en) 2016-11-02
KR102357337B1 (en) 2022-01-28
IL246395A0 (en) 2016-08-31
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