SG10201801804YA - Systems and methods for improved focus tracking using a hybrid mode light source - Google Patents

Systems and methods for improved focus tracking using a hybrid mode light source

Info

Publication number
SG10201801804YA
SG10201801804YA SG10201801804YA SG10201801804YA SG10201801804YA SG 10201801804Y A SG10201801804Y A SG 10201801804YA SG 10201801804Y A SG10201801804Y A SG 10201801804YA SG 10201801804Y A SG10201801804Y A SG 10201801804YA SG 10201801804Y A SG10201801804Y A SG 10201801804YA
Authority
SG
Singapore
Prior art keywords
focus tracking
light source
systems
methods
tracking beam
Prior art date
Application number
SG10201801804YA
Inventor
Danilo Condello
Simon Prince
David Hargis
Jeffrey Bendick
Christophe Sigel
Original Assignee
Illumina Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Illumina Inc filed Critical Illumina Inc
Publication of SG10201801804YA publication Critical patent/SG10201801804YA/en

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G02B21/241—Devices for focusing
    • G02B21/245—Devices for focusing using auxiliary sources, detectors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N23/00—Cameras or camera modules comprising electronic image sensors; Control thereof
    • H04N23/70—Circuitry for compensating brightness variation in the scene
    • H04N23/74—Circuitry for compensating brightness variation in the scene by influencing the scene brightness using illuminating means
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/06—Means for illuminating specimens
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G02B21/248—Base structure objective (or ocular) turrets
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/361—Optical details, e.g. image relay to the camera or image sensor
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/0075—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00 with means for altering, e.g. increasing, the depth of field or depth of focus
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/10—Beam splitting or combining systems
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B7/00—Mountings, adjusting means, or light-tight connections, for optical elements
    • G02B7/28—Systems for automatic generation of focusing signals
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01S—DEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
    • H01S5/00—Semiconductor lasers
    • H01S5/06—Arrangements for controlling the laser output parameters, e.g. by operating on the active medium
    • H01S5/065—Mode locking; Mode suppression; Mode selection ; Self pulsating
    • H01S5/0651—Mode control
    • H01S5/0653—Mode suppression, e.g. specific multimode

Abstract

SYSTEMS AND METHODS FOR IMPROVED FOCUS TRACKING USING A HYBRID MODE LIGHT SOURCE Systems and methods disclosed herein include an imaging system that may include a laser diode source; an objective lens positioned to direct a focus tracking beam from the light source onto a location in a sample container and to receive the focus tracking beam reflected from the sample; and an image sensor that may include a plurality of pixel locations to receive focus tracking beam that is reflected off of the location in the sample container, where the reflected focus tracking beam may create a spot on the image sensor. Some examples may further include a laser diode light source that may be operated at a power level that is above a power level for operation at an Amplified Spontaneous Emission (“ASE”) mode, but below a power level for single mode operation. [Figure 1]
SG10201801804YA 2017-03-07 2018-03-06 Systems and methods for improved focus tracking using a hybrid mode light source SG10201801804YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762468360P 2017-03-07 2017-03-07
NL2018853A NL2018853B1 (en) 2017-05-05 2017-05-05 Systems and methods for improved focus tracking using a hybrid mode light source

Publications (1)

Publication Number Publication Date
SG10201801804YA true SG10201801804YA (en) 2018-10-30

Family

ID=59974827

Family Applications (1)

Application Number Title Priority Date Filing Date
SG10201801804YA SG10201801804YA (en) 2017-03-07 2018-03-06 Systems and methods for improved focus tracking using a hybrid mode light source

Country Status (14)

Country Link
US (2) US10666872B2 (en)
EP (1) EP3373400A1 (en)
JP (2) JP6629369B2 (en)
KR (2) KR102060682B1 (en)
CN (2) CN108572140B (en)
AU (1) AU2018201428B2 (en)
CA (1) CA2997298C (en)
IL (2) IL257829A (en)
MY (1) MY189171A (en)
NL (1) NL2018853B1 (en)
NZ (1) NZ740301A (en)
SA (1) SA118390418B1 (en)
SG (1) SG10201801804YA (en)
TW (1) TWI707161B (en)

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Also Published As

Publication number Publication date
CA2997298C (en) 2019-10-01
KR20180102510A (en) 2018-09-17
MY189171A (en) 2022-01-31
IL257829A (en) 2018-04-30
SA118390418B1 (en) 2021-09-08
NZ740301A (en) 2019-09-27
EP3373400A1 (en) 2018-09-12
JP2020060770A (en) 2020-04-16
US20200259988A1 (en) 2020-08-13
KR20200000836A (en) 2020-01-03
AU2018201428A1 (en) 2018-09-27
IL279118A (en) 2021-01-31
CN108572140A (en) 2018-09-25
CN112525821A (en) 2021-03-19
KR102060682B1 (en) 2019-12-30
KR102365609B1 (en) 2022-02-18
IL279118B (en) 2022-04-01
CN108572140B (en) 2020-12-22
CA2997298A1 (en) 2018-09-07
BR102018004080A8 (en) 2022-11-16
AU2018201428B2 (en) 2019-02-28
TW201833627A (en) 2018-09-16
US10666872B2 (en) 2020-05-26
TWI707161B (en) 2020-10-11
BR102018004080A2 (en) 2018-12-04
NL2018853B1 (en) 2018-11-14
JP6629369B2 (en) 2020-01-15
US20180262670A1 (en) 2018-09-13
US11190706B2 (en) 2021-11-30
JP2018156070A (en) 2018-10-04

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