SG10201801098PA - Fluorescence Detection Instrument - Google Patents

Fluorescence Detection Instrument

Info

Publication number
SG10201801098PA
SG10201801098PA SG10201801098PA SG10201801098PA SG10201801098PA SG 10201801098P A SG10201801098P A SG 10201801098PA SG 10201801098P A SG10201801098P A SG 10201801098PA SG 10201801098P A SG10201801098P A SG 10201801098PA SG 10201801098P A SG10201801098P A SG 10201801098PA
Authority
SG
Singapore
Prior art keywords
module
heating
plural
holders
actuation
Prior art date
Application number
SG10201801098PA
Other languages
English (en)
Inventor
Bo Ma
Jei-Yin Yiu
Song-Bin Huang
Yu-Kai Kao
Chun-Jung Li
Po-Yao Huang
Original Assignee
Delta Electronics Int’L Singapore Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delta Electronics Int’L Singapore Pte Ltd filed Critical Delta Electronics Int’L Singapore Pte Ltd
Priority to SG10201801098PA priority Critical patent/SG10201801098PA/en
Priority to TW107106718A priority patent/TWI654311B/zh
Priority to US15/909,069 priority patent/US10620123B2/en
Priority to CN201810171977.8A priority patent/CN110132909B/zh
Publication of SG10201801098PA publication Critical patent/SG10201801098PA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6851Quantitative amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N21/0332Cuvette constructions with temperature control
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6486Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0654Lenses; Optical fibres
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0681Filter
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1838Means for temperature control using fluid heat transfer medium
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00Supporting devices; Holding devices
    • B01L9/06Test-tube stands; Test-tube holders
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N2021/6417Spectrofluorimetric devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/04Batch operation; multisample devices
    • G01N2201/0407Batch operation; multisample devices with multiple optical units, e.g. one per sample
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/06Illumination; Optics
    • G01N2201/068Optics, miscellaneous

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Clinical Laboratory Science (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
SG10201801098PA 2018-02-08 2018-02-08 Fluorescence Detection Instrument SG10201801098PA (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
SG10201801098PA SG10201801098PA (en) 2018-02-08 2018-02-08 Fluorescence Detection Instrument
TW107106718A TWI654311B (zh) 2018-02-08 2018-03-01 螢光偵測裝置
US15/909,069 US10620123B2 (en) 2018-02-08 2018-03-01 Fluorescence detection instrument
CN201810171977.8A CN110132909B (zh) 2018-02-08 2018-03-01 荧光检测装置

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SG10201801098PA SG10201801098PA (en) 2018-02-08 2018-02-08 Fluorescence Detection Instrument

Publications (1)

Publication Number Publication Date
SG10201801098PA true SG10201801098PA (en) 2019-09-27

Family

ID=66590821

Family Applications (1)

Application Number Title Priority Date Filing Date
SG10201801098PA SG10201801098PA (en) 2018-02-08 2018-02-08 Fluorescence Detection Instrument

Country Status (4)

Country Link
US (1) US10620123B2 (zh)
CN (1) CN110132909B (zh)
SG (1) SG10201801098PA (zh)
TW (1) TWI654311B (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3100340B1 (fr) * 2019-09-04 2021-07-30 Arteion Dispositif d’entraînement pour un appareil d’analyse automatique pour diagnostic in vitro
CN112881719B (zh) * 2019-11-30 2024-01-16 深圳市帝迈生物技术有限公司 血液分析仪、检测装置
CN112300924A (zh) * 2020-08-25 2021-02-02 墨卓生物科技(上海)有限公司 一体式pcr仪及其控制方法
CN114381361B (zh) * 2020-10-19 2024-02-13 台达电子国际(新加坡)私人有限公司 光活化装置及其控制方法
DE112021004082T5 (de) * 2020-12-14 2023-06-01 Suzhou Gendx Biotech Co., Ltd. Tragbare Fluoreszenzdetektionsvorrichtung
CN113391058A (zh) * 2021-05-25 2021-09-14 安徽惠邦生物工程有限公司 一种干式尿液分析仪的智能上加热模块
CN114705665A (zh) * 2022-06-02 2022-07-05 圣湘生物科技股份有限公司 荧光检测装置及荧光检测方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103499466B (zh) * 2006-01-18 2017-04-12 阿戈斯治疗公司 用于处理封闭容器中的样品的系统和方法以及相关装置
US7933011B2 (en) * 2007-07-12 2011-04-26 Smiths Detection Inc. Fiber optic detection system
FR2933192B1 (fr) * 2008-06-25 2010-09-17 Horiba Abx Sas Dispositif et procede de mesure electro optique destines a la classification et au comptage d'elements microscopiques.
JP6027321B2 (ja) 2012-03-06 2016-11-16 公益財団法人神奈川科学技術アカデミー 高速遺伝子増幅検出装置
CN105092544A (zh) * 2014-05-12 2015-11-25 绍兴安尼特微电子科技有限公司 一种荧光定量pcr检测仪光学激发和检测系统
CN104388307B (zh) * 2014-11-24 2016-05-25 中国科学院苏州生物医学工程技术研究所 一种液滴式样品荧光检测系统和方法
CN105524826A (zh) * 2016-01-12 2016-04-27 天津喜诺生物医药有限公司 一种qpcr多通道移动光源的检测装置
EP3460038B1 (en) 2016-05-18 2024-04-10 Go!Foton, Inc. Reaction treatment device, and method for controlling reaction treatment device
CN106525803B (zh) * 2016-12-12 2023-07-04 中国科学院苏州生物医学工程技术研究所 生物成像仪
CN106770114B (zh) * 2016-12-23 2018-03-13 西安交通大学 一种高通量测序碱基荧光识别系统装置与方法
CN106754292B (zh) 2017-01-12 2017-10-31 武汉菲思特生物科技有限公司 用于焦磷酸测序的dna单链分离器及分离方法

Also Published As

Publication number Publication date
US10620123B2 (en) 2020-04-14
TW201934759A (zh) 2019-09-01
CN110132909B (zh) 2023-03-24
CN110132909A (zh) 2019-08-16
US20190242822A1 (en) 2019-08-08
TWI654311B (zh) 2019-03-21

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