SG10201707233UA - Monoclonal antibody, inhibiting the enzymatic activity of vascular endothelial lipase - Google Patents

Monoclonal antibody, inhibiting the enzymatic activity of vascular endothelial lipase

Info

Publication number
SG10201707233UA
SG10201707233UA SG10201707233UA SG10201707233UA SG10201707233UA SG 10201707233U A SG10201707233U A SG 10201707233UA SG 10201707233U A SG10201707233U A SG 10201707233UA SG 10201707233U A SG10201707233U A SG 10201707233UA SG 10201707233U A SG10201707233U A SG 10201707233UA
Authority
SG
Singapore
Prior art keywords
inhibiting
monoclonal antibody
enzymatic activity
vascular endothelial
endothelial lipase
Prior art date
Application number
SG10201707233UA
Other languages
English (en)
Inventor
Shoichi Naito
Junji Onoda
Tasuku Tsukamoto
Katsutoshi Yamada
Shoji Yamane
Yoshito Numata
Kazuhiko Maekawa
Tatsuya Takahashi
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51536833&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG10201707233U(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of SG10201707233UA publication Critical patent/SG10201707233UA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/01—Carboxylic ester hydrolases (3.1.1)
    • C12Y301/01004—Phospholipase A2 (3.1.1.4)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG10201707233UA 2013-03-14 2014-03-12 Monoclonal antibody, inhibiting the enzymatic activity of vascular endothelial lipase SG10201707233UA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2013051995 2013-03-14

Publications (1)

Publication Number Publication Date
SG10201707233UA true SG10201707233UA (en) 2017-10-30

Family

ID=51536833

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201707233UA SG10201707233UA (en) 2013-03-14 2014-03-12 Monoclonal antibody, inhibiting the enzymatic activity of vascular endothelial lipase
SG11201507105RA SG11201507105RA (en) 2013-03-14 2014-03-12 Monoclonal antibody, inhibiting the enzymatic activity of vascular endothelial lipase

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201507105RA SG11201507105RA (en) 2013-03-14 2014-03-12 Monoclonal antibody, inhibiting the enzymatic activity of vascular endothelial lipase

Country Status (17)

Country Link
US (3) US9701757B2 (fr)
EP (1) EP2975060A4 (fr)
JP (1) JP6304775B2 (fr)
KR (1) KR102034478B1 (fr)
CN (1) CN105377896B (fr)
AU (1) AU2014230640B2 (fr)
BR (1) BR112015022009A2 (fr)
CA (1) CA2905597C (fr)
CL (1) CL2015002642A1 (fr)
IL (1) IL241097B (fr)
MX (1) MX365484B (fr)
MY (1) MY166357A (fr)
PH (1) PH12015502092A1 (fr)
RU (1) RU2662673C2 (fr)
SG (2) SG10201707233UA (fr)
WO (1) WO2014142182A1 (fr)
ZA (1) ZA201506536B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI688575B (zh) * 2014-09-11 2020-03-21 日商塩野義製藥股份有限公司 阻礙血管內皮脂酶之酵素活性的人類化單株抗體
CN107735105B (zh) * 2015-06-30 2022-09-16 西雅图基因公司 抗ntb-a抗体和相关组合物以及方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648267A (en) 1992-11-13 1997-07-15 Idec Pharmaceuticals Corporation Impaired dominant selectable marker sequence and intronic insertion strategies for enhancement of expression of gene product and expression vector systems comprising same
WO1999032611A1 (fr) * 1997-12-19 1999-07-01 Progenitor, Inc. Lipase exprimee dans des cellules endotheliales et procedes d'utilisation associes
MXPA01009727A (es) * 1999-03-26 2002-07-22 Aventis Pharma Inc Composiciones y metodos para afectar los niveles de colesterol asociado a lipoproteina de alta densidad (hdl) y a apolipoproteina a1, colesterol asociado a lipoproteina de muy baja densidad (vldl) y colesterol asociado a lipoproteina de baja densidad
NZ565878A (en) * 2005-07-21 2010-04-30 Reliance Life Sciences Pvt Ltd 2,5-substituted 3-undecyl-1,4-benzoquinones
US9296825B2 (en) 2011-10-12 2016-03-29 Shionogi & Co., Ltd. Monoclonal antibody against EL which inhibits enzyme activity of EL

Also Published As

Publication number Publication date
ZA201506536B (en) 2017-11-29
MX2015011923A (es) 2015-12-01
US10239955B2 (en) 2019-03-26
JP6304775B2 (ja) 2018-04-04
MY166357A (en) 2018-06-25
KR102034478B1 (ko) 2019-10-21
RU2662673C2 (ru) 2018-07-26
JPWO2014142182A1 (ja) 2017-02-16
CN105377896A (zh) 2016-03-02
US20190211114A1 (en) 2019-07-11
EP2975060A4 (fr) 2017-02-22
CA2905597C (fr) 2019-09-24
IL241097B (en) 2018-10-31
MX365484B (es) 2019-06-05
AU2014230640B2 (en) 2018-08-16
EP2975060A1 (fr) 2016-01-20
WO2014142182A1 (fr) 2014-09-18
US20160009819A1 (en) 2016-01-14
RU2015143477A (ru) 2017-04-20
PH12015502092A1 (en) 2016-01-18
CL2015002642A1 (es) 2016-03-18
IL241097A0 (en) 2015-11-30
SG11201507105RA (en) 2015-10-29
US20170275378A1 (en) 2017-09-28
AU2014230640A1 (en) 2015-09-17
US10745491B2 (en) 2020-08-18
KR20150127248A (ko) 2015-11-16
CN105377896B (zh) 2020-06-23
CA2905597A1 (fr) 2014-09-18
US9701757B2 (en) 2017-07-11
BR112015022009A2 (pt) 2017-08-29

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