SG10201704774VA - Novel recombinant factor c and method for producing the same, and method for measuring endotoxin - Google Patents
Novel recombinant factor c and method for producing the same, and method for measuring endotoxinInfo
- Publication number
- SG10201704774VA SG10201704774VA SG10201704774VA SG10201704774VA SG10201704774VA SG 10201704774V A SG10201704774V A SG 10201704774VA SG 10201704774V A SG10201704774V A SG 10201704774VA SG 10201704774V A SG10201704774V A SG 10201704774VA SG 10201704774V A SG10201704774V A SG 10201704774VA
- Authority
- SG
- Singapore
- Prior art keywords
- producing
- same
- recombinant factor
- novel recombinant
- measuring endotoxin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6402—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
- C12N9/6405—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals not being snakes
- C12N9/6408—Serine endopeptidases (3.4.21)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21084—Serine endopeptidases (3.4.21) limulus clotting factor C (3.4.21.84)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/579—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving limulus lysate
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96402—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals
- G01N2333/96405—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals in general
- G01N2333/96408—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals in general with EC number
- G01N2333/96411—Serine endopeptidases (3.4.21)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012269840 | 2012-12-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201704774VA true SG10201704774VA (en) | 2017-07-28 |
Family
ID=50934367
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201704774VA SG10201704774VA (en) | 2012-12-10 | 2013-12-10 | Novel recombinant factor c and method for producing the same, and method for measuring endotoxin |
| SG11201504564TA SG11201504564TA (en) | 2012-12-10 | 2013-12-10 | Novel recombinant factor c and method for producing the same, and method for measuring endotoxin |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201504564TA SG11201504564TA (en) | 2012-12-10 | 2013-12-10 | Novel recombinant factor c and method for producing the same, and method for measuring endotoxin |
Country Status (7)
| Country | Link |
|---|---|
| US (6) | US10144923B2 (ja) |
| EP (4) | EP3441466B1 (ja) |
| JP (2) | JP6511685B2 (ja) |
| CN (3) | CN108642030A (ja) |
| ES (2) | ES2738593T3 (ja) |
| SG (2) | SG10201704774VA (ja) |
| WO (1) | WO2014092079A1 (ja) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6511685B2 (ja) * | 2012-12-10 | 2019-05-15 | 生化学工業株式会社 | 新規組換えファクターｃ、その製造法、およびエンドトキシンの測定法 |
| EP3343217A4 (en) * | 2015-08-24 | 2018-09-26 | Shimadzu Corporation | Separation/purification apparatus |
| WO2017141961A1 (ja) | 2016-02-16 | 2017-08-24 | 生化学工業株式会社 | フェニレンジアミン誘導体を用いた電気化学測定 |
| EP3530670B1 (en) * | 2016-10-18 | 2024-02-28 | Seikagaku Corporation | Method for producing endotoxin detecting agent comprising recombinant limulus factor c and use thereof |
| CN110366592B (zh) * | 2017-03-01 | 2024-01-23 | 生化学工业株式会社 | 鲎b因子改变体 |
| WO2019073846A1 (ja) | 2017-10-10 | 2019-04-18 | 大日本印刷株式会社 | 薬剤収容容器、閉鎖部材、薬剤収容容器の製造方法、および微生物夾雑物検査方法、ならびに緩衝液調製用固形剤 |
| WO2020071229A1 (ja) | 2018-10-03 | 2020-04-09 | 生化学工業株式会社 | エンドトキシン測定剤の感度の増強方法 |
| CN110628917B (zh) * | 2019-09-27 | 2022-06-14 | 北部湾大学 | 一种中国鲎ssr引物组及其应用 |
| WO2021210669A1 (ja) | 2020-04-16 | 2021-10-21 | キッコーマン株式会社 | 加水分解酵素を利用した微量物質の測定方法 |
| CN112359059B (zh) * | 2020-11-10 | 2021-11-30 | 北部湾大学 | 用于表达rFC蛋白的84E突变载体及其制备方法和应用 |
| US20240125789A1 (en) * | 2021-02-12 | 2024-04-18 | Charles River Laboratories, Inc. | Hybrid amebocyte lysate and uses thereof |
| EP4382597A1 (en) | 2021-08-04 | 2024-06-12 | Seikagaku Corporation | Reagent for measuring ?-glucan, method for producing same and use thereof |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3242733B2 (ja) | 1993-02-26 | 2001-12-25 | 生化学工業株式会社 | エンドトキシン特異的測定剤 |
| JP2006087435A (ja) | 1993-06-29 | 2006-04-06 | Seikagaku Kogyo Co Ltd | 新規ポリペプチド及びそれをコードするｄｎａ |
| US5795962A (en) | 1993-06-29 | 1998-08-18 | Seikagaku Kogyo Kabushiki Kaisha | Horseshoe crab amebocyte lysate factor G subunit A |
| US5716834A (en) * | 1994-08-19 | 1998-02-10 | National University Of Singapore | Cloned factor C cDNA of the Singapore horseshoe crab, Carcinoscorpius rotundicauda and purification of factor C proenzyme |
| SG94673A1 (en) | 1996-02-03 | 2003-03-18 | Univ Singapore | Expression of carcinoscorpius rotundicauda factor c in eukaryotes |
| WO1999015676A1 (en) * | 1997-09-19 | 1999-04-01 | National University Of Singapore | A novel generation of cloned horseshoe crab recombinant factor c for detection and removal of endotoxin |
| US6645724B1 (en) | 1997-09-19 | 2003-11-11 | National University Of Singapore | Assays for endotoxin |
| US6733997B1 (en) * | 1998-10-30 | 2004-05-11 | National University Of Singapore | Isolated nucleic acids encoding a secretory signal for expression and secretion of heterologous recombinant proteins |
| WO2002046437A2 (en) | 2000-12-05 | 2002-06-13 | The Penn State Research Foundation | Methods and compositions for highly efficient production of heterologous proteins in yeast |
| PT1409984E (pt) | 2001-06-28 | 2009-10-29 | Lonza Walkersville Inc | Processos e reagentes para a detecção de endotoxinas |
| AU2005306356A1 (en) | 2004-11-19 | 2006-05-26 | Biogen Idec Ma Inc. | Methods for producing mammalian cells |
| EP2495322A1 (en) * | 2006-07-07 | 2012-09-05 | Seikagaku Corporation | Pro-clotting enzyme, and method for detection of (1 --> 3) -ß-D-glucan using the same |
| EP1953222A1 (en) | 2007-01-24 | 2008-08-06 | Boehringer Ingelheim Pharma GmbH & Co. KG | Improvement of cell growth |
| TWI532495B (zh) | 2009-10-05 | 2016-05-11 | 菲瑞茵國際中心股份有限公司 | 藥學製劑 |
| AU2011350456B2 (en) | 2010-12-28 | 2016-05-26 | Chugai Seiyaku Kabushiki Kaisha | Animal cell culturing method |
| SG192578A1 (en) | 2011-02-28 | 2013-09-30 | Seikagaku Kogyo Co Ltd | An agent for measuring endotoxin |
| JP6511685B2 (ja) | 2012-12-10 | 2019-05-15 | 生化学工業株式会社 | 新規組換えファクターｃ、その製造法、およびエンドトキシンの測定法 |
-
2013
- 2013-12-10 JP JP2014552048A patent/JP6511685B2/ja active Active
- 2013-12-10 US US14/650,767 patent/US10144923B2/en active Active
- 2013-12-10 CN CN201810483329.6A patent/CN108642030A/zh active Pending
- 2013-12-10 CN CN201810481773.4A patent/CN108646019B/zh active Active
- 2013-12-10 EP EP18190686.8A patent/EP3441466B1/en active Active
- 2013-12-10 SG SG10201704774VA patent/SG10201704774VA/en unknown
- 2013-12-10 WO PCT/JP2013/083082 patent/WO2014092079A1/ja active Application Filing
- 2013-12-10 EP EP13862466.3A patent/EP2930241B1/en active Active
- 2013-12-10 ES ES13862466T patent/ES2738593T3/es active Active
- 2013-12-10 SG SG11201504564TA patent/SG11201504564TA/en unknown
- 2013-12-10 CN CN201380064649.3A patent/CN104919046A/zh active Pending
- 2013-12-10 EP EP22215393.4A patent/EP4219705A1/en active Pending
- 2013-12-10 ES ES18190686T patent/ES2784510T3/es active Active
- 2013-12-10 EP EP19216609.8A patent/EP3663400A1/en active Pending
-
2018
- 2018-05-18 US US15/983,725 patent/US10982202B2/en active Active
- 2018-09-28 JP JP2018183630A patent/JP6626174B2/ja active Active
-
2019
- 2019-04-30 US US16/399,386 patent/US11236318B2/en active Active
- 2019-04-30 US US16/399,575 patent/US20190256835A1/en not_active Abandoned
-
2021
- 2021-12-17 US US17/554,128 patent/US20220145280A1/en active Pending
-
2023
- 2023-07-03 US US18/346,420 patent/US20230357742A1/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| CN108646019A (zh) | 2018-10-12 |
| US20150307864A1 (en) | 2015-10-29 |
| WO2014092079A1 (ja) | 2014-06-19 |
| EP2930241A4 (en) | 2016-08-03 |
| US20230357742A1 (en) | 2023-11-09 |
| SG11201504564TA (en) | 2015-08-28 |
| EP3441466A1 (en) | 2019-02-13 |
| EP3663400A1 (en) | 2020-06-10 |
| JPWO2014092079A1 (ja) | 2017-01-12 |
| EP3441466B1 (en) | 2020-02-05 |
| CN104919046A (zh) | 2015-09-16 |
| US20190270977A1 (en) | 2019-09-05 |
| ES2784510T3 (es) | 2020-09-28 |
| EP2930241A1 (en) | 2015-10-14 |
| ES2738593T3 (es) | 2020-01-23 |
| JP6511685B2 (ja) | 2019-05-15 |
| EP4219705A1 (en) | 2023-08-02 |
| CN108642030A (zh) | 2018-10-12 |
| US20190256835A1 (en) | 2019-08-22 |
| US10144923B2 (en) | 2018-12-04 |
| US10982202B2 (en) | 2021-04-20 |
| US20180258414A1 (en) | 2018-09-13 |
| EP2930241B1 (en) | 2019-06-26 |
| JP2019000122A (ja) | 2019-01-10 |
| CN108646019B (zh) | 2021-06-25 |
| US11236318B2 (en) | 2022-02-01 |
| US20220145280A1 (en) | 2022-05-12 |
| JP6626174B2 (ja) | 2019-12-25 |
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