SG10201610356YA - Dual receptor antagonistic antigen-binding proteins and uses thereof - Google Patents
Dual receptor antagonistic antigen-binding proteins and uses thereofInfo
- Publication number
- SG10201610356YA SG10201610356YA SG10201610356YA SG10201610356YA SG10201610356YA SG 10201610356Y A SG10201610356Y A SG 10201610356YA SG 10201610356Y A SG10201610356Y A SG 10201610356YA SG 10201610356Y A SG10201610356Y A SG 10201610356YA SG 10201610356Y A SG10201610356Y A SG 10201610356YA
- Authority
- SG
- Singapore
- Prior art keywords
- binding proteins
- receptor antagonistic
- antagonistic antigen
- dual receptor
- dual
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261658237P | 2012-06-11 | 2012-06-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201610356YA true SG10201610356YA (en) | 2017-01-27 |
Family
ID=49758865
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201408228QA SG11201408228QA (en) | 2012-06-11 | 2013-06-11 | Dual receptor antagonistic antigen-binding proteins and uses thereof |
| SG10201610356YA SG10201610356YA (en) | 2012-06-11 | 2013-06-11 | Dual receptor antagonistic antigen-binding proteins and uses thereof |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201408228QA SG11201408228QA (en) | 2012-06-11 | 2013-06-11 | Dual receptor antagonistic antigen-binding proteins and uses thereof |
Country Status (21)
| Country | Link |
|---|---|
| US (5) | US9453080B2 (en) |
| EP (3) | EP3540070A1 (en) |
| JP (1) | JP2015525230A (en) |
| KR (1) | KR20150030706A (en) |
| CN (1) | CN104540961A (en) |
| AU (1) | AU2013274347B2 (en) |
| BR (1) | BR112014031028A2 (en) |
| CA (1) | CA2877669A1 (en) |
| CL (1) | CL2014003372A1 (en) |
| CO (1) | CO7240399A2 (en) |
| EA (1) | EA201492282A1 (en) |
| HK (1) | HK1208499A1 (en) |
| IL (1) | IL236133A0 (en) |
| MA (1) | MA37761A1 (en) |
| MX (1) | MX2014015195A (en) |
| NZ (1) | NZ703724A (en) |
| PE (1) | PE20150642A1 (en) |
| PH (1) | PH12014502754A1 (en) |
| SG (2) | SG11201408228QA (en) |
| TN (2) | TN2015000448A1 (en) |
| WO (1) | WO2013188448A2 (en) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112014031028A2 (en) * | 2012-06-11 | 2017-08-15 | Amgen Inc | ANTIGEN-BINDING PROTEIN ISOLATED, NUCLLEIC ACID ISOLATED, EXPRESSION VECTOR, HOST CELL, METHOD FOR PRODUCING AN ANTIGEN-BINDING PROTEIN, COMPOSITION, METHOD FOR REDUCING OR BLOCKING THE ACTIVITY OF MYOSTATIN, ACTIVIN A OR GDF-11, METHOD FOR ENHANCEMENT MUSCLE MASS FIRMNESS OR INCREASE THE MUSCLE MASS FIRMITY TO FAT MASS RATIO IN AN INDIVIDUAL IN NEED OF THE MENTIONED TREATMENT, METHOD FOR TREATMENT OR PREVENTION OF A HARMFUL DISEASE OF MUSCLE IN AN INDIVIDUAL SUFFERING FROM THE SAID DISORDER AND DUAL ANTAGONIST RECEPTOR ANTIBODY |
| PL2895503T3 (en) | 2012-09-13 | 2019-09-30 | Bristol-Myers Squibb Company | Fibronectin based scaffold domain proteins that bind to myostatin |
| CA2969800A1 (en) * | 2014-12-08 | 2016-06-16 | Novartis Ag | Myostatin or activin antagonists for the treatment of sarcopenia |
| GB201500464D0 (en) * | 2015-01-12 | 2015-02-25 | Crescendo Biolog Ltd | Method of producing optimised therapeutic molecules |
| WO2017147182A1 (en) * | 2016-02-22 | 2017-08-31 | Acceleron Pharma Inc. | Actrii antagonists for use in increasing immune activity |
| KR20230152153A (en) | 2016-03-10 | 2023-11-02 | 악셀레론 파마 인코포레이티드 | Activin type 2 receptor binding proteins and uses thereof |
| JP7139326B2 (en) | 2016-11-10 | 2022-09-20 | ケロス セラピューティクス インコーポレイテッド | ACTIVIN TYPE IIa RECEPTOR MUTANTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME MUTANTS |
| JOP20190152A1 (en) * | 2016-12-21 | 2019-06-20 | Novartis Ag | Myostatin, activin or activin receptor antagonists for use in treating obesity and related conditions |
| WO2018162931A1 (en) * | 2017-03-10 | 2018-09-13 | Ucl Business Plc | Method relating to myostatin pathway inhibition |
| US11104737B2 (en) | 2017-03-28 | 2021-08-31 | Rigel Pharmaceuticals, Inc. | ACVR2A-specific antibody and method of treatment of muscle atrophy |
| US11484573B2 (en) | 2017-11-09 | 2022-11-01 | Keros Therapeutics, Inc. | Activin receptor type IIa variants and methods of use thereof |
| JP7510875B2 (en) | 2018-01-12 | 2024-07-04 | ケロス セラピューティクス インコーポレイテッド | Activin type IIB receptor mutants and pharmaceutical compositions containing the same |
| WO2020243448A1 (en) * | 2019-05-30 | 2020-12-03 | Acceleron Pharma Inc. | Actrii-binding proteins and uses thereof |
| EP4121088A4 (en) * | 2020-03-20 | 2024-07-03 | Keros Therapeutics Inc | Methods of using activin receptor type iib variants |
| WO2021189006A1 (en) * | 2020-03-20 | 2021-09-23 | Keros Therapeutics, Inc. | Methods of using activin receptor type iia variants |
Family Cites Families (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| FR2413974A1 (en) | 1978-01-06 | 1979-08-03 | David Bernard | DRYER FOR SCREEN-PRINTED SHEETS |
| JPS6023084B2 (en) | 1979-07-11 | 1985-06-05 | 味の素株式会社 | blood substitute |
| US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4640835A (en) | 1981-10-30 | 1987-02-03 | Nippon Chemiphar Company, Ltd. | Plasminogen activator derivatives |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4496689A (en) | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
| US4740461A (en) | 1983-12-27 | 1988-04-26 | Genetics Institute, Inc. | Vectors and methods for transformation of eucaryotic cells |
| DE3675588D1 (en) | 1985-06-19 | 1990-12-20 | Ajinomoto Kk | HAEMOGLOBIN TIED TO A POLY (ALKENYLENE OXIDE). |
| US4676980A (en) | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
| US4791192A (en) | 1986-06-26 | 1988-12-13 | Takeda Chemical Industries, Ltd. | Chemically modified protein with polyethyleneglycol |
| US4959455A (en) | 1986-07-14 | 1990-09-25 | Genetics Institute, Inc. | Primate hematopoietic growth factors IL-3 and pharmaceutical compositions |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| ATE87659T1 (en) | 1986-09-02 | 1993-04-15 | Enzon Lab Inc | BINDING MOLECULES WITH SINGLE POLYPEPTIDE CHAIN. |
| US5260203A (en) | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
| US4912040A (en) | 1986-11-14 | 1990-03-27 | Genetics Institute, Inc. | Eucaryotic expression system |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5175384A (en) | 1988-12-05 | 1992-12-29 | Genpharm International | Transgenic mice depleted in mature t-cells and methods for making transgenic mice |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| ATE144793T1 (en) | 1989-06-29 | 1996-11-15 | Medarex Inc | BISPECIFIC REAGENTS FOR AIDS THERAPY |
| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| FR2664073A1 (en) | 1990-06-29 | 1992-01-03 | Thomson Csf | MEANS FOR MARKING OBJECTS, METHOD FOR PRODUCING THE SAME, AND DEVICE FOR READING. |
| AU8295491A (en) | 1990-06-29 | 1992-01-23 | Biosource Technologies Incorporated | Melanin production by transformed microorganisms |
| US5814318A (en) | 1990-08-29 | 1998-09-29 | Genpharm International Inc. | Transgenic non-human animals for producing heterologous antibodies |
| DK0814159T3 (en) | 1990-08-29 | 2005-10-24 | Genpharm Int | Transgenic, non-human animals capable of forming heterologous antibodies |
| US5612205A (en) | 1990-08-29 | 1997-03-18 | Genpharm International, Incorporated | Homologous recombination in mammalian cells |
| US5789650A (en) | 1990-08-29 | 1998-08-04 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5770429A (en) | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5877397A (en) | 1990-08-29 | 1999-03-02 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US6255458B1 (en) | 1990-08-29 | 2001-07-03 | Genpharm International | High affinity human antibodies and human antibodies against digoxin |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5874299A (en) | 1990-08-29 | 1999-02-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US6300129B1 (en) | 1990-08-29 | 2001-10-09 | Genpharm International | Transgenic non-human animals for producing heterologous antibodies |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| WO1992020373A1 (en) | 1991-05-14 | 1992-11-26 | Repligen Corporation | Heteroconjugate antibodies for treatment of hiv infection |
| WO1992022670A1 (en) | 1991-06-12 | 1992-12-23 | Genpharm International, Inc. | Early detection of transgenic embryos |
| WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| AU2235992A (en) | 1991-06-14 | 1993-01-12 | Genpharm International, Inc. | Transgenic immunodeficient non-human animals |
| WO1993004169A1 (en) | 1991-08-20 | 1993-03-04 | Genpharm International, Inc. | Gene targeting in animal cells using isogenic dna constructs |
| ES2136092T3 (en) | 1991-09-23 | 1999-11-16 | Medical Res Council | PROCEDURES FOR THE PRODUCTION OF HUMANIZED ANTIBODIES. |
| WO1993008829A1 (en) | 1991-11-04 | 1993-05-13 | The Regents Of The University Of California | Compositions that mediate killing of hiv-infected cells |
| ES2202310T3 (en) | 1991-12-13 | 2004-04-01 | Xoma Corporation | METHODS AND MATERIALS FOR THE PREPARATION OF VARIABLE DOMAINS OF MODIFIED ANTIBODIES AND THEIR THERAPEUTIC USES. |
| US5869619A (en) | 1991-12-13 | 1999-02-09 | Xoma Corporation | Modified antibody variable domains |
| CA2124967C (en) | 1991-12-17 | 2008-04-08 | Nils Lonberg | Transgenic non-human animals capable of producing heterologous antibodies |
| AU4541093A (en) | 1992-06-18 | 1994-01-24 | Genpharm International, Inc. | Methods for producing transgenic non-human animals harboring a yeast artificial chromosome |
| US6066718A (en) | 1992-09-25 | 2000-05-23 | Novartis Corporation | Reshaped monoclonal antibodies against an immunoglobulin isotype |
| US5981175A (en) | 1993-01-07 | 1999-11-09 | Genpharm Internation, Inc. | Methods for producing recombinant mammalian cells harboring a yeast artificial chromosome |
| CA2161351C (en) | 1993-04-26 | 2010-12-21 | Nils Lonberg | Transgenic non-human animals capable of producing heterologous antibodies |
| US5625825A (en) | 1993-10-21 | 1997-04-29 | Lsi Logic Corporation | Random number generating apparatus for an interface unit of a carrier sense with multiple access and collision detect (CSMA/CD) ethernet data network |
| US5643763A (en) | 1994-11-04 | 1997-07-01 | Genpharm International, Inc. | Method for making recombinant yeast artificial chromosomes by minimizing diploid doubling during mating |
| US6133426A (en) | 1997-02-21 | 2000-10-17 | Genentech, Inc. | Humanized anti-IL-8 monoclonal antibodies |
| US6660843B1 (en) | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
| EP1278778A2 (en) | 2000-05-03 | 2003-01-29 | Amgen Inc., | Modified peptides, comprising an fc domain, as therapeutic agents |
| DK2332977T3 (en) * | 2004-07-23 | 2016-02-29 | Acceleron Pharma Inc | ActRII receptor polypeptides |
| US20100120627A1 (en) * | 2006-08-02 | 2010-05-13 | Abdelmajid Belouchi | Genemap of the human genes associated with psoriasis |
| WO2013106175A1 (en) | 2011-12-19 | 2013-07-18 | Amgen Inc. | Variant activin receptor polypeptides, alone or in combination with chemotherapy, and uses thereof |
| TWI573802B (en) | 2007-03-06 | 2017-03-11 | 安美基公司 | Variant activin receptor polypeptides and uses thereof |
| SG171813A1 (en) | 2008-11-26 | 2011-07-28 | Amgen Inc | Variants of activin iib receptor polypeptides and uses thereof |
| MY153078A (en) * | 2009-04-27 | 2014-12-31 | Novartis Ag | Compositions and methods for increasing muscle growth |
| US8524217B2 (en) * | 2010-05-11 | 2013-09-03 | Merck Sharp & Dohme Corp. | MCP1-Ig fusion variants |
| BR112014031028A2 (en) * | 2012-06-11 | 2017-08-15 | Amgen Inc | ANTIGEN-BINDING PROTEIN ISOLATED, NUCLLEIC ACID ISOLATED, EXPRESSION VECTOR, HOST CELL, METHOD FOR PRODUCING AN ANTIGEN-BINDING PROTEIN, COMPOSITION, METHOD FOR REDUCING OR BLOCKING THE ACTIVITY OF MYOSTATIN, ACTIVIN A OR GDF-11, METHOD FOR ENHANCEMENT MUSCLE MASS FIRMNESS OR INCREASE THE MUSCLE MASS FIRMITY TO FAT MASS RATIO IN AN INDIVIDUAL IN NEED OF THE MENTIONED TREATMENT, METHOD FOR TREATMENT OR PREVENTION OF A HARMFUL DISEASE OF MUSCLE IN AN INDIVIDUAL SUFFERING FROM THE SAID DISORDER AND DUAL ANTAGONIST RECEPTOR ANTIBODY |
| JP6071725B2 (en) | 2013-04-23 | 2017-02-01 | カルソニックカンセイ株式会社 | Driving force control device for electric vehicles |
-
2013
- 2013-06-11 BR BR112014031028A patent/BR112014031028A2/en not_active IP Right Cessation
- 2013-06-11 WO PCT/US2013/045245 patent/WO2013188448A2/en active Application Filing
- 2013-06-11 MX MX2014015195A patent/MX2014015195A/en unknown
- 2013-06-11 EP EP19169804.2A patent/EP3540070A1/en active Pending
- 2013-06-11 MA MA37761A patent/MA37761A1/en unknown
- 2013-06-11 NZ NZ703724A patent/NZ703724A/en not_active IP Right Cessation
- 2013-06-11 EA EA201492282A patent/EA201492282A1/en unknown
- 2013-06-11 CN CN201380042597.XA patent/CN104540961A/en active Pending
- 2013-06-11 SG SG11201408228QA patent/SG11201408228QA/en unknown
- 2013-06-11 TN TN2015000448A patent/TN2015000448A1/en unknown
- 2013-06-11 US US14/407,421 patent/US9453080B2/en active Active
- 2013-06-11 CA CA2877669A patent/CA2877669A1/en not_active Abandoned
- 2013-06-11 JP JP2015517364A patent/JP2015525230A/en not_active Withdrawn
- 2013-06-11 EP EP13804428.4A patent/EP2859114B1/en active Active
- 2013-06-11 PE PE2014002415A patent/PE20150642A1/en not_active Application Discontinuation
- 2013-06-11 AU AU2013274347A patent/AU2013274347B2/en not_active Expired - Fee Related
- 2013-06-11 SG SG10201610356YA patent/SG10201610356YA/en unknown
- 2013-06-11 KR KR1020157000579A patent/KR20150030706A/en not_active Application Discontinuation
- 2013-06-11 EP EP18203126.0A patent/EP3498857A1/en active Pending
-
2014
- 2014-12-08 IL IL236133A patent/IL236133A0/en unknown
- 2014-12-09 PH PH12014502754A patent/PH12014502754A1/en unknown
- 2014-12-10 TN TN2014000513A patent/TN2014000513A1/en unknown
- 2014-12-11 CL CL2014003372A patent/CL2014003372A1/en unknown
-
2015
- 2015-01-08 CO CO15003908A patent/CO7240399A2/en unknown
- 2015-09-14 HK HK15108981.7A patent/HK1208499A1/en unknown
-
2016
- 2016-08-25 US US15/247,792 patent/US10266598B2/en active Active
-
2019
- 2019-03-05 US US16/293,254 patent/US10981999B2/en active Active
-
2021
- 2021-03-18 US US17/205,144 patent/US20210340262A1/en not_active Abandoned
-
2023
- 2023-10-19 US US18/381,745 patent/US20240327526A1/en active Pending
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