SG10201606883QA - Benzofuran compounds for the treatment of hepatitis c virus infections - Google Patents
Benzofuran compounds for the treatment of hepatitis c virus infectionsInfo
- Publication number
- SG10201606883QA SG10201606883QA SG10201606883QA SG10201606883QA SG10201606883QA SG 10201606883Q A SG10201606883Q A SG 10201606883QA SG 10201606883Q A SG10201606883Q A SG 10201606883QA SG 10201606883Q A SG10201606883Q A SG 10201606883QA SG 10201606883Q A SG10201606883Q A SG 10201606883QA
- Authority
- SG
- Singapore
- Prior art keywords
- hepatitis
- treatment
- virus infections
- benzofuran compounds
- benzofuran
- Prior art date
Links
- 150000001907 coumarones Chemical class 0.000 title 1
- 208000010710 hepatitis C virus infection Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/027—Organoboranes and organoborohydrides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/04—Esters of boric acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161525440P | 2011-08-19 | 2011-08-19 | |
| US201261650681P | 2012-05-23 | 2012-05-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201606883QA true SG10201606883QA (en) | 2016-10-28 |
Family
ID=47746761
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201606883QA SG10201606883QA (en) | 2011-08-19 | 2012-08-10 | Benzofuran compounds for the treatment of hepatitis c virus infections |
Country Status (37)
| Country | Link |
|---|---|
| US (2) | US8927593B2 (de) |
| EP (2) | EP2744332B1 (de) |
| JP (2) | JP6367712B2 (de) |
| KR (1) | KR101913800B1 (de) |
| CN (1) | CN103732065B (de) |
| AR (1) | AR087563A1 (de) |
| AU (1) | AU2012299295B2 (de) |
| BR (1) | BR112014002845A2 (de) |
| CA (1) | CA2844086A1 (de) |
| CL (2) | CL2014000393A1 (de) |
| CO (1) | CO6862153A2 (de) |
| CR (1) | CR20140078A (de) |
| CY (1) | CY1118399T1 (de) |
| DK (1) | DK2744332T3 (de) |
| DO (1) | DOP2014000034A (de) |
| EA (1) | EA032841B1 (de) |
| ES (1) | ES2611731T3 (de) |
| HR (1) | HRP20161743T1 (de) |
| HU (1) | HUE030300T2 (de) |
| IL (1) | IL230487B (de) |
| IN (1) | IN2014CN00572A (de) |
| JO (1) | JO3281B1 (de) |
| LT (1) | LT2744332T (de) |
| MA (1) | MA35443B1 (de) |
| ME (1) | ME02588B (de) |
| MX (1) | MX354676B (de) |
| PE (1) | PE20141201A1 (de) |
| PL (1) | PL2744332T3 (de) |
| PT (1) | PT2744332T (de) |
| RS (1) | RS55462B1 (de) |
| SG (1) | SG10201606883QA (de) |
| SI (1) | SI2744332T1 (de) |
| SM (1) | SMT201700028B (de) |
| TW (1) | TWI538915B (de) |
| UY (1) | UY34274A (de) |
| WO (1) | WO2013028371A1 (de) |
| ZA (1) | ZA201401020B (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201606646RA (en) | 2011-08-17 | 2016-09-29 | Glaxosmithkline Llc | Therapeutic methods |
| IN2014CN00572A (de) | 2011-08-19 | 2015-04-03 | Glaxo Group Ltd | |
| MX2017006138A (es) | 2014-11-10 | 2017-11-16 | Glaxosmithkline Intellectual Property (No 2) Ltd | Composiciones farmaceuticas de accion prolongada para hepatitis c. |
| SG11201703646SA (en) * | 2014-11-10 | 2017-06-29 | Glaxosmithkline Intellectual Property (No 2) Ltd | Combination long acting compositions and methods for hepatitis c |
| KR20180006522A (ko) | 2016-07-07 | 2018-01-18 | 삼성디스플레이 주식회사 | 액정 조성물 및 이를 포함하는 액정 표시 장치 |
| US11738088B2 (en) | 2016-08-01 | 2023-08-29 | University of Pittsburgh—of the Commonwealth System of Higher Education | Boryl ethers, carbonates, and cyclic acetals as oxidatively-triggered drug delivery vehicles |
| EP3589630B1 (de) * | 2017-03-02 | 2021-07-07 | Assembly Biosciences, Inc. | Cyclische sulfamidverbindungen und verfahren zur verwendung davon |
| EP3740489A1 (de) * | 2018-01-17 | 2020-11-25 | GlaxoSmithKline Intellectual Property Development Limited | Pi4kiiibeta-hemmer |
| CA3155559A1 (en) * | 2019-10-25 | 2021-04-29 | Sachiko Koike | Novel substituted condensed ring compound |
| CN111026203B (zh) * | 2019-12-02 | 2021-01-26 | 宁波德晶元科技有限公司 | 一种适用于真空热水壶的加热控制方法与系统 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6083903A (en) | 1994-10-28 | 2000-07-04 | Leukosite, Inc. | Boronic ester and acid compounds, synthesis and uses |
| CA2376965A1 (en) | 1999-07-07 | 2001-01-11 | Timothy Patrick Forsyth | Peptide boronic acid inhibitors of hepatitis c virus protease |
| JP4162491B2 (ja) | 2001-01-25 | 2008-10-08 | アメリカ合衆国 | ボロン酸化合物製剤 |
| CN1731993A (zh) | 2002-11-01 | 2006-02-08 | 维洛药品公司 | 苯并呋喃化合物、组合物以及治疗和预防丙型肝炎病毒感染及相关疾病的方法 |
| CA2631024A1 (en) | 2005-12-01 | 2008-05-02 | Wyeth | Anthranilic acid derivatives useful in treating infection with hepatitis c virus |
| KR101819869B1 (ko) | 2006-02-16 | 2018-01-17 | 아나코르 파마슈티칼스 인코포레이티드 | 항염증제로서 보론함유 소분자 |
| US8106031B2 (en) * | 2006-05-02 | 2012-01-31 | Anacor Pharmaceuticals, Inc. | Hydrolytically-resistant boron-containing therapeutics and methods of use |
| US20070286822A1 (en) | 2006-06-12 | 2007-12-13 | Anacor Pharmaceuticals Inc. | Compounds for the Treatment of Periodontal Disease |
| EP2532643A1 (de) * | 2007-06-08 | 2012-12-12 | MannKind Corporation | IRE-1a-Inhibitoren |
| GB0719366D0 (en) * | 2007-10-03 | 2007-11-14 | Smithkline Beecham Corp | Compounds |
| RU2010137635A (ru) * | 2008-02-14 | 2012-03-20 | Ф.Хоффманн-Ля Рош Аг (Ch) | Гетероциклические антивирусные соединения |
| EP2187893A4 (de) | 2008-03-06 | 2012-02-22 | Anacor Pharmaceuticals Inc | Kleine boronhaltige moleküle als entzündungshemmende wirkstoffe |
| WO2009137500A1 (en) * | 2008-05-05 | 2009-11-12 | Wyeth | 6-substituted benzofuran compounds to treat infection with hepatitis c virus |
| WO2009137493A1 (en) | 2008-05-05 | 2009-11-12 | Wyeth | 2-substituted benzofuran compounds to treat infection with hepatitis c virus |
| TW201008933A (en) | 2008-08-29 | 2010-03-01 | Hutchison Medipharma Entpr Ltd | Pyrimidine compounds |
| EP2348863A4 (de) | 2008-09-04 | 2012-03-07 | Anacor Pharmaceuticals Inc | Borhaltige kleine moleküle |
| WO2011050284A1 (en) * | 2009-10-23 | 2011-04-28 | Glaxosmithkline Llc | Pyrazolylpyridine antiviral agents |
| TW201138786A (en) | 2010-02-19 | 2011-11-16 | Glaxo Group Ltd | Therapeutic compounds |
| TW201136919A (en) | 2010-03-02 | 2011-11-01 | Merck Sharp & Amp Dohme Corp | Inhibitors of hepatitis C virus NS5B polymerase |
| WO2011106986A1 (en) | 2010-03-02 | 2011-09-09 | Merck Sharp & Dohme Corp. | Inhibitors of hepatitis c virus ns5b polymerase |
| WO2011106929A1 (en) | 2010-03-02 | 2011-09-09 | Merck Sharp & Dohme Corp. | Inhibitors of hepatitis c virus ns5b polymerase |
| AU2011329485A1 (en) | 2010-11-18 | 2013-04-18 | Glaxo Group Limited | Compounds |
| AU2011329486A1 (en) | 2010-11-18 | 2013-04-18 | Glaxo Group Limited | Compounds |
| WO2013025975A1 (en) * | 2011-08-17 | 2013-02-21 | Glaxosmithkline Llc | Combination treatments for hepatitis c |
| SG10201606646RA (en) * | 2011-08-17 | 2016-09-29 | Glaxosmithkline Llc | Therapeutic methods |
| IN2014CN00572A (de) | 2011-08-19 | 2015-04-03 | Glaxo Group Ltd |
-
2012
- 2012-08-10 IN IN572CHN2014 patent/IN2014CN00572A/en unknown
- 2012-08-10 AU AU2012299295A patent/AU2012299295B2/en not_active Ceased
- 2012-08-10 CN CN201280040219.3A patent/CN103732065B/zh not_active Expired - Fee Related
- 2012-08-10 DK DK12826498.3T patent/DK2744332T3/en active
- 2012-08-10 EP EP12826498.3A patent/EP2744332B1/de active Active
- 2012-08-10 MX MX2014001989A patent/MX354676B/es active IP Right Grant
- 2012-08-10 ES ES12826498.3T patent/ES2611731T3/es active Active
- 2012-08-10 SI SI201230826A patent/SI2744332T1/sl unknown
- 2012-08-10 SG SG10201606883QA patent/SG10201606883QA/en unknown
- 2012-08-10 EP EP16195408.6A patent/EP3199531A1/de not_active Withdrawn
- 2012-08-10 RS RS20161131A patent/RS55462B1/sr unknown
- 2012-08-10 PE PE2014000197A patent/PE20141201A1/es not_active Application Discontinuation
- 2012-08-10 EA EA201490213A patent/EA032841B1/ru not_active IP Right Cessation
- 2012-08-10 PL PL12826498T patent/PL2744332T3/pl unknown
- 2012-08-10 HU HUE12826498A patent/HUE030300T2/en unknown
- 2012-08-10 LT LTEP12826498.3T patent/LT2744332T/lt unknown
- 2012-08-10 WO PCT/US2012/050268 patent/WO2013028371A1/en active Application Filing
- 2012-08-10 CA CA2844086A patent/CA2844086A1/en not_active Abandoned
- 2012-08-10 US US13/885,500 patent/US8927593B2/en not_active Expired - Fee Related
- 2012-08-10 PT PT128264983T patent/PT2744332T/pt unknown
- 2012-08-10 BR BR112014002845A patent/BR112014002845A2/pt not_active Application Discontinuation
- 2012-08-10 ME MEP-2016-287A patent/ME02588B/de unknown
- 2012-08-10 JP JP2014526090A patent/JP6367712B2/ja not_active Expired - Fee Related
- 2012-08-10 KR KR1020147007196A patent/KR101913800B1/ko active IP Right Grant
- 2012-08-16 JO JOP/2012/0233A patent/JO3281B1/ar active
- 2012-08-16 AR ARP120103008A patent/AR087563A1/es unknown
- 2012-08-17 UY UY0001034274A patent/UY34274A/es not_active Application Discontinuation
- 2012-08-17 TW TW101130017A patent/TWI538915B/zh not_active IP Right Cessation
-
2014
- 2014-01-16 IL IL230487A patent/IL230487B/en not_active IP Right Cessation
- 2014-01-23 CO CO14013113A patent/CO6862153A2/es active IP Right Grant
- 2014-02-10 ZA ZA201401020A patent/ZA201401020B/en unknown
- 2014-02-17 CL CL2014000393A patent/CL2014000393A1/es unknown
- 2014-02-18 CR CR20140078A patent/CR20140078A/es unknown
- 2014-02-19 DO DO2014000034A patent/DOP2014000034A/es unknown
- 2014-03-13 MA MA36832A patent/MA35443B1/fr unknown
- 2014-11-20 US US14/548,524 patent/US9682999B2/en not_active Expired - Fee Related
-
2016
- 2016-12-19 HR HRP20161743TT patent/HRP20161743T1/hr unknown
- 2016-12-22 JP JP2016249387A patent/JP2017125010A/ja active Pending
- 2016-12-27 CY CY20161101345T patent/CY1118399T1/el unknown
-
2017
- 2017-01-18 SM SM201700028T patent/SMT201700028B/it unknown
- 2017-02-03 CL CL2017000293A patent/CL2017000293A1/es unknown
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