SG10201509139QA - Novel iso-ergoline derivatives - Google Patents

Novel iso-ergoline derivatives

Info

Publication number
SG10201509139QA
SG10201509139QA SG10201509139QA SG10201509139QA SG10201509139QA SG 10201509139Q A SG10201509139Q A SG 10201509139QA SG 10201509139Q A SG10201509139Q A SG 10201509139QA SG 10201509139Q A SG10201509139Q A SG 10201509139QA SG 10201509139Q A SG10201509139Q A SG 10201509139QA
Authority
SG
Singapore
Prior art keywords
ergoline derivatives
novel iso
iso
novel
ergoline
Prior art date
Application number
SG10201509139QA
Other languages
English (en)
Inventor
Jian Zhang
Robert O Cook
Original Assignee
Map Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Map Pharmaceuticals Inc filed Critical Map Pharmaceuticals Inc
Publication of SG10201509139QA publication Critical patent/SG10201509139QA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/02—Ergot alkaloids of the cyclic peptide type

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG10201509139QA 2011-12-19 2012-06-22 Novel iso-ergoline derivatives SG10201509139QA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161577563P 2011-12-19 2011-12-19

Publications (1)

Publication Number Publication Date
SG10201509139QA true SG10201509139QA (en) 2015-12-30

Family

ID=48610738

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201403434YA SG11201403434YA (en) 2011-12-19 2012-06-22 Novel iso-ergoline derivatives
SG10201509139QA SG10201509139QA (en) 2011-12-19 2012-06-22 Novel iso-ergoline derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11201403434YA SG11201403434YA (en) 2011-12-19 2012-06-22 Novel iso-ergoline derivatives

Country Status (7)

Country Link
US (3) US8592445B2 (fr)
EP (1) EP2793580A4 (fr)
AU (1) AU2012355982A1 (fr)
CA (1) CA2859173A1 (fr)
IL (1) IL233001A0 (fr)
SG (2) SG11201403434YA (fr)
WO (1) WO2013095707A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2013015373A (es) * 2011-06-23 2014-02-11 Map Pharmaceuticals Inc Nuevos analogos de fluoroergolina.
SG11201403434YA (en) * 2011-12-19 2014-09-26 Map Pharmaceuticals Inc Novel iso-ergoline derivatives
BR112017015487A2 (pt) * 2015-01-20 2018-01-30 Xoc Pharmaceuticals Inc Composto; composição; método de tratamento e/ou prevenção de enxaqueca, als, doença de alzheimer, doença de parkinson, distúrbios extrapirimidais, depressão, náusea, êmese, síndrome das pernas inquietas, insônia, agressão, doença de huntington, doença cardiopulmonar, fibrogênese, hipertensão arterial pulmonar, ansiedade, dependências a drogas, distonia, parassonia ou hiperlactinemia em um indivíduo; métodos de agonização dos receptores d2, 5-ht1d, 5-ht1a e 5-ht2c, em um indivíduo; método de antagonização do receptor d3 em um indivíduo; métodos de agonização seletiva dos receptores 5 -ht1d, e 5-ht2c, método de fornecimento de atividade de antagonista funcional no receptor 5 -ht2b ou no receptor 5-ht7, ou em ambos, em um indivíduo; método de fornecimento de atividade de antagonista funcional nos receptores adrenérgicos em um indivíduo
JP2018502889A (ja) 2015-01-20 2018-02-01 エックスオーシー ファーマシューティカルズ インコーポレイテッドＸｏｃ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ イソエルゴリン化合物およびその使用
WO2018223065A1 (fr) 2017-06-01 2018-12-06 Xoc Pharmaceuticals, Inc. Dérivés d'ergoline destinés à être utilisés en médecine

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Also Published As

Publication number Publication date
US20130158064A1 (en) 2013-06-20
WO2013095707A1 (fr) 2013-06-27
EP2793580A1 (fr) 2014-10-29
EP2793580A4 (fr) 2015-05-20
CA2859173A1 (fr) 2013-06-27
US20140094483A1 (en) 2014-04-03
US8722699B2 (en) 2014-05-13
US8969374B2 (en) 2015-03-03
US8592445B2 (en) 2013-11-26
SG11201403434YA (en) 2014-09-26
US20140039188A1 (en) 2014-02-06
AU2012355982A1 (en) 2014-07-10
IL233001A0 (en) 2014-07-31

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