SE9903998D0 - New compounds - Google Patents

New compounds

Info

Publication number
SE9903998D0
SE9903998D0 SE9903998A SE9903998A SE9903998D0 SE 9903998 D0 SE9903998 D0 SE 9903998D0 SE 9903998 A SE9903998 A SE 9903998A SE 9903998 A SE9903998 A SE 9903998A SE 9903998 D0 SE9903998 D0 SE 9903998D0
Authority
SE
Sweden
Prior art keywords
sup
new compounds
compounds
nicotinic
reductions
Prior art date
Application number
SE9903998A
Other languages
English (en)
Swedish (sv)
Inventor
David Gurley
James Rosamond
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9903998A priority Critical patent/SE9903998D0/xx
Publication of SE9903998D0 publication Critical patent/SE9903998D0/xx
Priority to US10/111,029 priority patent/US7064143B1/en
Priority to JP2001534774A priority patent/JP2003513073A/ja
Priority to IL14909600A priority patent/IL149096A0/xx
Priority to KR1020027005705A priority patent/KR20020063175A/ko
Priority to AU14263/01A priority patent/AU783602B2/en
Priority to EP00976499A priority patent/EP1230218A1/en
Priority to CN008154406A priority patent/CN1216864C/zh
Priority to MXPA02004240A priority patent/MXPA02004240A/es
Priority to PCT/SE2000/002147 priority patent/WO2001032622A1/en
Priority to CA002387741A priority patent/CA2387741A1/en
Priority to CO00083137A priority patent/CO5280079A1/es
Priority to NZ518449A priority patent/NZ518449A/en
Priority to BR0015193-9A priority patent/BR0015193A/pt
Priority to ZA200203181A priority patent/ZA200203181B/xx
Priority to NO20022105A priority patent/NO323077B1/no
Priority to US11/178,668 priority patent/US7402604B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Pyridine Compounds (AREA)
SE9903998A 1999-11-03 1999-11-03 New compounds SE9903998D0 (sv)

Priority Applications (17)

Application Number Priority Date Filing Date Title
SE9903998A SE9903998D0 (sv) 1999-11-03 1999-11-03 New compounds
BR0015193-9A BR0015193A (pt) 1999-11-03 2000-11-01 Composto, composição farmacêutica, uso de um composto, e, método para tratamento de uma condição associada com trasmissão reduzida de nicotina, para tratamento ou profilaxia de distúrbios psicóticos ou distúrbios de deterioração intelectual e para tratamento ou profilaxia de doenças ou condições humanas
EP00976499A EP1230218A1 (en) 1999-11-03 2000-11-01 Positive modulators of nicotinic receptor agonists
MXPA02004240A MXPA02004240A (es) 1999-11-03 2000-11-01 Moduladores positivos de agonistas de receptores nicotinicos.
IL14909600A IL149096A0 (en) 1999-11-03 2000-11-01 Positive modulators of nicotinic receptor agonists
KR1020027005705A KR20020063175A (ko) 1999-11-03 2000-11-01 니코틴 수용체 작용물질의 양성 조절자
AU14263/01A AU783602B2 (en) 1999-11-03 2000-11-01 Positive modulators of nicotinic receptor agonists
US10/111,029 US7064143B1 (en) 1999-11-03 2000-11-01 Positive modulators of nicotinic receptor agonists
CN008154406A CN1216864C (zh) 1999-11-03 2000-11-01 烟碱性受体激动剂的正调节剂
JP2001534774A JP2003513073A (ja) 1999-11-03 2000-11-01 ニコチン受容体作用薬の正のモジュレーター
PCT/SE2000/002147 WO2001032622A1 (en) 1999-11-03 2000-11-01 Positive modulators of nicotinic receptor agonists
CA002387741A CA2387741A1 (en) 1999-11-03 2000-11-01 Positive modulators of nicotinic receptor agonists
CO00083137A CO5280079A1 (es) 1999-11-03 2000-11-01 Nuevos compuestos
NZ518449A NZ518449A (en) 1999-11-03 2000-11-01 Positive modulators of nicotinic receptor agonists
ZA200203181A ZA200203181B (en) 1999-11-03 2002-04-22 Positive modulators of nicotinic receptor agonists.
NO20022105A NO323077B1 (no) 1999-11-03 2002-05-02 Forbindelse, farmasoytisk preparat, nevnte forbindelse eller preparat for medisinsk bruk samt anvendelse av nevnte forbindelse for fremstilling av et medikament for medisinsk behandling.
US11/178,668 US7402604B2 (en) 1999-11-03 2005-07-11 Positive modulators of nicotinic receptor agonists

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9903998A SE9903998D0 (sv) 1999-11-03 1999-11-03 New compounds

Publications (1)

Publication Number Publication Date
SE9903998D0 true SE9903998D0 (sv) 1999-11-03

Family

ID=20417608

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9903998A SE9903998D0 (sv) 1999-11-03 1999-11-03 New compounds

Country Status (16)

Country Link
US (2) US7064143B1 (https=)
EP (1) EP1230218A1 (https=)
JP (1) JP2003513073A (https=)
KR (1) KR20020063175A (https=)
CN (1) CN1216864C (https=)
AU (1) AU783602B2 (https=)
BR (1) BR0015193A (https=)
CA (1) CA2387741A1 (https=)
CO (1) CO5280079A1 (https=)
IL (1) IL149096A0 (https=)
MX (1) MXPA02004240A (https=)
NO (1) NO323077B1 (https=)
NZ (1) NZ518449A (https=)
SE (1) SE9903998D0 (https=)
WO (1) WO2001032622A1 (https=)
ZA (1) ZA200203181B (https=)

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WO2003039540A2 (en) * 2001-11-09 2003-05-15 Sepracor Inc. D-amino acid oxidase inhibitors for learning and memory
DE10164139A1 (de) 2001-12-27 2003-07-10 Bayer Ag 2-Heteroarylcarbonsäureamide
GB0205165D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205162D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205166D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205170D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205175D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205176D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
JP2006501246A (ja) 2002-08-30 2006-01-12 メモリー・ファーマシューティカルズ・コーポレイション 神経変性疾患の治療において有用なアナバセイン誘導体
MXPA05003317A (es) 2002-09-25 2005-07-05 Memory Pharm Corp Indazoles, benzotiazoles y benzoisotiazoles asi como preparacion y usos de los mismos.
GB0222912D0 (en) 2002-10-03 2002-11-13 Astrazeneca Ab Novel process and intermediates
GB0222909D0 (en) 2002-10-03 2002-11-13 Astrazeneca Ab Novel process and intermediates
US7405210B2 (en) 2003-05-21 2008-07-29 Osi Pharmaceuticals, Inc. Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase
JP2007517056A (ja) 2003-12-29 2007-06-28 セプラコア インコーポレーテッド ピロール及びピラゾールｄａａｏ阻害剤
JP2007527904A (ja) 2004-03-08 2007-10-04 プロシディオン・リミテッド グリコーゲンホスホリラーゼ阻害剤としてのピロロピリジン−２−カルボン酸ヒドラジド化合物
NZ550534A (en) 2004-03-25 2009-07-31 Memory Pharm Corp Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof
ES2340180T3 (es) 2004-06-01 2010-05-31 F.Hoffmann-La Roche Ag 3-amino-1-arilpropil-indoles como inhibidores de reabsorcion de monoaminas.
JP5254616B2 (ja) 2004-09-13 2013-08-07 クロノ セラピューティクス、インコーポレイテッド 生物学的同調性（ｂｉｏｓｙｎｃｈｒｏｎｏｕｓ）経皮的薬物送達
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
US7223786B2 (en) 2004-11-15 2007-05-29 Bristol-Myers Squibb Company 2-aminonaphthalene derivatives and related glycogen phosphorylase inhibitors
WO2006055462A1 (en) 2004-11-15 2006-05-26 Bristol-Myers Squibb Company 2-amino-4-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors
WO2006053274A2 (en) 2004-11-15 2006-05-18 Bristol-Myers Squibb Company 2-amino-1-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors
US7365061B2 (en) 2004-11-15 2008-04-29 Bristol-Myers Squibb Company 2-Amino-3-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors
ES2324173T3 (es) 2004-12-02 2009-07-31 Prosidion Limited Amidas del acido pirrolopiridin-2-carboxilico.
FR2888847B1 (fr) 2005-07-22 2007-08-31 Sanofi Aventis Sa Derives de n-(heteriaryl)-1-heteorarylalkyl-1h-indole-2- carboxamides, leur preparation et application en therapeutique
KR20080080593A (ko) 2005-11-30 2008-09-04 에프. 호프만-라 로슈 아게 3-아미노-1-아릴프로필 인돌의 합성 방법
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JP2009517430A (ja) 2005-11-30 2009-04-30 エフ．ホフマン−ラ ロシュ アーゲー ３−アミノ−１−アリールプロピルインドール類及びアザ置換インドール類
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EP1944288A1 (en) * 2007-01-09 2008-07-16 Bayer Schering Pharma Aktiengesellschaft Radiolabelling via fluorination of aziridines
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US8383657B2 (en) 2007-12-21 2013-02-26 Abbott Laboratories Thiazolylidine urea and amide derivatives and methods of use thereof
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EP3801732A4 (en) 2018-05-29 2022-04-27 Morningside Venture Investments Limited METHODS AND SYSTEMS FOR DRUG DELIVERY
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SE9903997D0 (sv) * 1999-11-03 1999-11-03 Astra Ab New compounds

Also Published As

Publication number Publication date
NO20022105L (no) 2002-07-02
CN1216864C (zh) 2005-08-31
JP2003513073A (ja) 2003-04-08
WO2001032622A1 (en) 2001-05-10
EP1230218A1 (en) 2002-08-14
US7064143B1 (en) 2006-06-20
US7402604B2 (en) 2008-07-22
IL149096A0 (en) 2002-11-10
ZA200203181B (en) 2003-07-22
CO5280079A1 (es) 2003-05-30
MXPA02004240A (es) 2002-10-17
NZ518449A (en) 2004-07-30
CN1387513A (zh) 2002-12-25
CA2387741A1 (en) 2001-05-10
KR20020063175A (ko) 2002-08-01
BR0015193A (pt) 2002-06-18
NO323077B1 (no) 2006-12-27
US20050245595A1 (en) 2005-11-03
AU1426301A (en) 2001-05-14
NO20022105D0 (no) 2002-05-02
AU783602B2 (en) 2005-11-10

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