SE9902741D0 - Method for the enrichment of heteroduplexes and its use in mutation detection - Google Patents

Method for the enrichment of heteroduplexes and its use in mutation detection

Info

Publication number
SE9902741D0
SE9902741D0 SE9902741A SE9902741A SE9902741D0 SE 9902741 D0 SE9902741 D0 SE 9902741D0 SE 9902741 A SE9902741 A SE 9902741A SE 9902741 A SE9902741 A SE 9902741A SE 9902741 D0 SE9902741 D0 SE 9902741D0
Authority
SE
Sweden
Prior art keywords
heteroduplexes
nucleic acid
protein
selectively
enrichment
Prior art date
Application number
SE9902741A
Other languages
English (en)
Inventor
Boerries Kemper
Stefan Golz
Original Assignee
Boerries Kemper
Stefan Golz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boerries Kemper, Stefan Golz filed Critical Boerries Kemper
Priority to SE9902741A priority Critical patent/SE9902741D0/sv
Publication of SE9902741D0 publication Critical patent/SE9902741D0/sv
Priority to PCT/EP2000/006829 priority patent/WO2001005800A2/en
Priority to AU66948/00A priority patent/AU6694800A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SE9902741A 1999-07-18 1999-07-19 Method for the enrichment of heteroduplexes and its use in mutation detection SE9902741D0 (sv)

Priority Applications (3)

Application Number Priority Date Filing Date Title
SE9902741A SE9902741D0 (sv) 1999-07-19 1999-07-19 Method for the enrichment of heteroduplexes and its use in mutation detection
PCT/EP2000/006829 WO2001005800A2 (en) 1999-07-18 2000-07-18 A method for the enrichment of heteroduplexes and its use in mutation detection
AU66948/00A AU6694800A (en) 1999-07-18 2000-07-18 A method for the enrichment of heteroduplexes and its use in mutation detection

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9902741A SE9902741D0 (sv) 1999-07-19 1999-07-19 Method for the enrichment of heteroduplexes and its use in mutation detection

Publications (1)

Publication Number Publication Date
SE9902741D0 true SE9902741D0 (sv) 1999-07-19

Family

ID=20416533

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9902741A SE9902741D0 (sv) 1999-07-18 1999-07-19 Method for the enrichment of heteroduplexes and its use in mutation detection

Country Status (3)

Country Link
AU (1) AU6694800A (sv)
SE (1) SE9902741D0 (sv)
WO (1) WO2001005800A2 (sv)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2102365A4 (en) * 2006-12-29 2010-06-09 Applied Biosystems Llc ENRICHMENT THROUGH HETERODUPLEX MOLECULES
US9279146B2 (en) * 2012-12-21 2016-03-08 Roche Molecular Systems, Inc. Compounds and methods for the enrichment of mutated nucleic acid from a mixture
US9873908B2 (en) 2013-11-27 2018-01-23 Roche Molecular Systems, Inc. Methods for the enrichment of mutated nucleic acid from a mixture

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993020233A1 (en) * 1992-03-27 1993-10-14 University Of Maryland At Baltimore Detection of gene mutations with mismatch repair enzymes
WO1995029251A1 (en) * 1994-04-25 1995-11-02 Applied Technology Genetics Corporation Detection of mutation by resolvase cleavage
WO1996035809A1 (en) * 1995-05-11 1996-11-14 Avitech Diagnostics Inc Detection of mismatches by resolvase cleavage on a solid support
WO1997009434A1 (en) * 1995-09-08 1997-03-13 University Of Dundee Dna structure-specific nucleases
DE19757144A1 (de) * 1997-12-20 1999-06-24 Boerries Prof Dr Rer Na Kemper Dualer enzymatischer Test zum Nachweis von Mutationen in DNA beliebiger Herkunft durch Endonuklease VII

Also Published As

Publication number Publication date
WO2001005800A2 (en) 2001-01-25
AU6694800A (en) 2001-02-05
WO2001005800A3 (en) 2001-05-10

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