AU6694800A - A method for the enrichment of heteroduplexes and its use in mutation detection - Google Patents

A method for the enrichment of heteroduplexes and its use in mutation detection

Info

Publication number
AU6694800A
AU6694800A AU66948/00A AU6694800A AU6694800A AU 6694800 A AU6694800 A AU 6694800A AU 66948/00 A AU66948/00 A AU 66948/00A AU 6694800 A AU6694800 A AU 6694800A AU 6694800 A AU6694800 A AU 6694800A
Authority
AU
Australia
Prior art keywords
heteroduplexes
enrichment
mutation detection
mutation
detection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU66948/00A
Inventor
Stefan Golz
Borries Kemper
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of AU6694800A publication Critical patent/AU6694800A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU66948/00A 1999-07-18 2000-07-18 A method for the enrichment of heteroduplexes and its use in mutation detection Abandoned AU6694800A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9902741 1999-07-18
SE9902741A SE9902741D0 (en) 1999-07-19 1999-07-19 Method for the enrichment of heteroduplexes and its use in mutation detection
PCT/EP2000/006829 WO2001005800A2 (en) 1999-07-18 2000-07-18 A method for the enrichment of heteroduplexes and its use in mutation detection

Publications (1)

Publication Number Publication Date
AU6694800A true AU6694800A (en) 2001-02-05

Family

ID=20416533

Family Applications (1)

Application Number Title Priority Date Filing Date
AU66948/00A Abandoned AU6694800A (en) 1999-07-18 2000-07-18 A method for the enrichment of heteroduplexes and its use in mutation detection

Country Status (3)

Country Link
AU (1) AU6694800A (en)
SE (1) SE9902741D0 (en)
WO (1) WO2001005800A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008083327A2 (en) 2006-12-29 2008-07-10 Applied Biosystems, Llc Enrichment through heteroduplexed molecules
US9279146B2 (en) * 2012-12-21 2016-03-08 Roche Molecular Systems, Inc. Compounds and methods for the enrichment of mutated nucleic acid from a mixture
US9873908B2 (en) * 2013-11-27 2018-01-23 Roche Molecular Systems, Inc. Methods for the enrichment of mutated nucleic acid from a mixture

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3919293A (en) * 1992-03-27 1993-11-08 University Of Maryland At Baltimore Detection of gene mutations with mismatch repair enzymes
DE69531612D1 (en) * 1994-04-25 2003-10-02 Avitech Diagnostics Inc DETERMINATION OF MUTATIONS BY CUTTING WITH RESOLVASE
EP0843736B1 (en) * 1995-05-11 1999-12-22 Ulf Landegren Detection of mismatches by resolvase cleavage on a solid support
WO1997009434A1 (en) * 1995-09-08 1997-03-13 University Of Dundee Dna structure-specific nucleases
DE19757144A1 (en) * 1997-12-20 1999-06-24 Boerries Prof Dr Rer Na Kemper Detection of genomic mutations

Also Published As

Publication number Publication date
WO2001005800A2 (en) 2001-01-25
SE9902741D0 (en) 1999-07-19
WO2001005800A3 (en) 2001-05-10

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase