SE9801424D0 - Expression methods - Google Patents

Expression methods

Info

Publication number
SE9801424D0
SE9801424D0 SE9801424A SE9801424A SE9801424D0 SE 9801424 D0 SE9801424 D0 SE 9801424D0 SE 9801424 A SE9801424 A SE 9801424A SE 9801424 A SE9801424 A SE 9801424A SE 9801424 D0 SE9801424 D0 SE 9801424D0
Authority
SE
Sweden
Prior art keywords
bssl
relates
human
methods
transgenic
Prior art date
Application number
SE9801424A
Other languages
English (en)
Inventor
Michael Dalrymple
Lennart Lundberg
Mats Stroemqivst
Original Assignee
Astra Ab
Ppl Therapeutics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab, Ppl Therapeutics filed Critical Astra Ab
Priority to SE9801424A priority Critical patent/SE9801424D0/sv
Publication of SE9801424D0 publication Critical patent/SE9801424D0/sv
Priority to PCT/SE1999/000648 priority patent/WO1999054443A1/en
Priority to CA002325871A priority patent/CA2325871A1/en
Priority to US09/355,295 priority patent/US6525241B1/en
Priority to JP2000544775A priority patent/JP2002512021A/ja
Priority to AU44011/99A priority patent/AU758725B2/en
Priority to EP99927011A priority patent/EP1071755A1/en
Priority to NZ507331A priority patent/NZ507331A/xx
Priority to KR1020007011732A priority patent/KR20010042918A/ko
Priority to CN99807612A priority patent/CN1306568A/zh
Priority to NO20005297A priority patent/NO20005297L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A01K67/0278—Knock-in vertebrates, e.g. humanised vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00—Modified animals
    • A01K2207/15—Humanized animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/103—Ovine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/01—Animal expressing industrially exogenous proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Environmental Sciences (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Diabetes (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
SE9801424A 1998-04-22 1998-04-22 Expression methods SE9801424D0 (sv)

Priority Applications (11)

Application Number Priority Date Filing Date Title
SE9801424A SE9801424D0 (sv) 1998-04-22 1998-04-22 Expression methods
CN99807612A CN1306568A (zh) 1998-04-22 1999-04-21 可得自转基因羊的胆汁盐活化的人脂肪酶(bssl)
JP2000544775A JP2002512021A (ja) 1998-04-22 1999-04-21 トランスジェニックヒツジから得られるヒト胆汁酸塩−刺激リパーゼ（ｂｓｓｌ）
CA002325871A CA2325871A1 (en) 1998-04-22 1999-04-21 Human bile salt-stimulated lipase (bssl) obtainable from transgenic sheep
US09/355,295 US6525241B1 (en) 1998-04-22 1999-04-21 Expression methods
PCT/SE1999/000648 WO1999054443A1 (en) 1998-04-22 1999-04-21 Human bile salt-stimulated lipase (bssl) obtainable from transgenic sheep
AU44011/99A AU758725B2 (en) 1998-04-22 1999-04-21 Human bile salt-stimulated lipase (BSSL) obtainable from transgenic sheep
EP99927011A EP1071755A1 (en) 1998-04-22 1999-04-21 Human bile salt-stimulated lipase (bssl) obtainable from transgenic sheep
NZ507331A NZ507331A (en) 1998-04-22 1999-04-21 Glycosylated bile salt-stimulated lipase (BSSL) obtainable from transgenic sheep
KR1020007011732A KR20010042918A (ko) 1998-04-22 1999-04-21 유전자 이식된 양에서 수득한 인간 담즙산염-자극리파아제 (ｂｓｓｌ)
NO20005297A NO20005297L (no) 1998-04-22 2000-10-20 Human gallesaltstimulert lipase (BSSL) erholdbar fra transgen sau

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9801424A SE9801424D0 (sv) 1998-04-22 1998-04-22 Expression methods

Publications (1)

Publication Number Publication Date
SE9801424D0 true SE9801424D0 (sv) 1998-04-22

Family

ID=20411065

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9801424A SE9801424D0 (sv) 1998-04-22 1998-04-22 Expression methods

Country Status (11)

Country Link
US (1) US6525241B1 (sv)
EP (1) EP1071755A1 (sv)
JP (1) JP2002512021A (sv)
KR (1) KR20010042918A (sv)
CN (1) CN1306568A (sv)
AU (1) AU758725B2 (sv)
CA (1) CA2325871A1 (sv)
NO (1) NO20005297L (sv)
NZ (1) NZ507331A (sv)
SE (1) SE9801424D0 (sv)
WO (1) WO1999054443A1 (sv)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001055440A1 (en) * 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies
AU2001283062A1 (en) 2000-08-02 2002-02-13 The Johns Hopkins University Endothelial cell expression patterns
JP3930334B2 (ja) * 2001-03-21 2007-06-13 株式会社資生堂 分光反射率測定装置
CA2812852A1 (en) 2010-10-21 2012-04-26 Swedish Orphan Biovitrum Ab (Publ) Method to increase the absorption of unsaturated fatty acids by human infants
JP5850940B2 (ja) * 2010-10-21 2016-02-03 スウェディッシュ オーファン バイオビトラム パブリーク アクチエボラグ ヒト乳児の発育速度を増大させる方法
RU2013156071A (ru) * 2011-05-18 2015-06-27 Сведиш Орфан Биовитрум Аб (Пабл) СПОСОБ ОЧИСТКИ БЕЛКОВ ПРИ НИЗКОМ pH
CN103088000A (zh) * 2012-03-23 2013-05-08 北京济福霖生物技术有限公司 在哺乳动物乳腺中过表达胆盐激活脂酶的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP930935A2 (en) * 1992-06-11 1994-12-31 Astra Ab New dna sequences
IS4130A (is) * 1993-03-01 1994-09-02 Ab Astra Ný fjölpeptíð

Also Published As

Publication number Publication date
CN1306568A (zh) 2001-08-01
AU4401199A (en) 1999-11-08
WO1999054443A1 (en) 1999-10-28
NO20005297L (no) 2000-11-13
US6525241B1 (en) 2003-02-25
JP2002512021A (ja) 2002-04-23
CA2325871A1 (en) 1999-10-28
NZ507331A (en) 2003-01-31
KR20010042918A (ko) 2001-05-25
AU758725B2 (en) 2003-03-27
NO20005297D0 (no) 2000-10-20
EP1071755A1 (en) 2001-01-31

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