SE9701228D0 - Rekombinanta protein-C-och protein-S-varianter - Google Patents
Rekombinanta protein-C-och protein-S-varianterInfo
- Publication number
- SE9701228D0 SE9701228D0 SE9701228A SE9701228A SE9701228D0 SE 9701228 D0 SE9701228 D0 SE 9701228D0 SE 9701228 A SE9701228 A SE 9701228A SE 9701228 A SE9701228 A SE 9701228A SE 9701228 D0 SE9701228 D0 SE 9701228D0
- Authority
- SE
- Sweden
- Prior art keywords
- protein
- component
- wild
- amino acid
- variants
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6464—Protein C (3.4.21.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9701228A SE9701228D0 (sv) | 1997-04-03 | 1997-04-03 | Rekombinanta protein-C-och protein-S-varianter |
EP98915077A EP0996637A1 (en) | 1997-04-03 | 1998-03-18 | Recombinant protein c and protein s variants |
JP54152998A JP2002501373A (ja) | 1997-04-03 | 1998-03-18 | 組換えプロテインc及びプロテインs変異体 |
PCT/SE1998/000490 WO1998044000A1 (en) | 1997-04-03 | 1998-03-18 | Recombinant protein c and protein s variants |
NZ337800A NZ337800A (en) | 1997-04-03 | 1998-03-18 | Recombinant protein C and protein S variants |
CA002283934A CA2283934A1 (en) | 1997-04-03 | 1998-03-18 | Recombinant protein c and protein s variants |
AU69345/98A AU741798B2 (en) | 1997-04-03 | 1998-03-18 | Recombinant protein C and protein S variants |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9701228A SE9701228D0 (sv) | 1997-04-03 | 1997-04-03 | Rekombinanta protein-C-och protein-S-varianter |
Publications (1)
Publication Number | Publication Date |
---|---|
SE9701228D0 true SE9701228D0 (sv) | 1997-04-03 |
Family
ID=20406428
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9701228A SE9701228D0 (sv) | 1997-04-03 | 1997-04-03 | Rekombinanta protein-C-och protein-S-varianter |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0996637A1 (sv) |
JP (1) | JP2002501373A (sv) |
AU (1) | AU741798B2 (sv) |
CA (1) | CA2283934A1 (sv) |
NZ (1) | NZ337800A (sv) |
SE (1) | SE9701228D0 (sv) |
WO (1) | WO1998044000A1 (sv) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6998122B1 (en) | 1999-04-30 | 2006-02-14 | Eli Lilly And Company | Protein C derivatives |
DE60108076T2 (de) | 2000-02-02 | 2006-03-16 | Eli Lilly And Co., Indianapolis | Protein c derivate |
US6630138B2 (en) | 2000-02-11 | 2003-10-07 | Eli Lilly And Company | Protein C derivatives |
US6933367B2 (en) | 2000-10-18 | 2005-08-23 | Maxygen Aps | Protein C or activated protein C-like molecules |
AU2003212739B2 (en) * | 2002-03-01 | 2008-01-17 | T.A.C. Thrombosis And Coagulation Aktiebolag | Recombinant protein C variants |
WO2003106666A2 (en) * | 2002-06-14 | 2003-12-24 | Maxygen Aps | Protein c variants with altered properties |
WO2023119230A1 (en) | 2021-12-22 | 2023-06-29 | L'oreal | Coagulation pathway and nicotinamide-adenine dinucleotide pathway modulating compositions and methods of their use |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE464135B (sv) * | 1989-07-14 | 1991-03-11 | Kabivitrum Ab | Foerfarande foer bestaemning av funktionell aktivitet av fritt protein s eller protein c i ett plasmaprov |
IL97311A0 (en) * | 1990-02-23 | 1992-05-25 | Lilly Co Eli | Vectors and compounds for expression of glycosylation mutants of human protein c |
US5405946A (en) * | 1992-12-02 | 1995-04-11 | The Scripps Research Institute | Recombinant protein S variants deficient in C4BP binding activity, compositions and therapeutic methods |
JPH08511948A (ja) * | 1993-06-30 | 1996-12-17 | リークスウニフエルジタイト・ライデン | C4bp結合活性が不足しているがapc補因子活性を有するプロテインs欠失変異体、組成物及び治療法 |
-
1997
- 1997-04-03 SE SE9701228A patent/SE9701228D0/sv unknown
-
1998
- 1998-03-18 EP EP98915077A patent/EP0996637A1/en not_active Withdrawn
- 1998-03-18 AU AU69345/98A patent/AU741798B2/en not_active Ceased
- 1998-03-18 CA CA002283934A patent/CA2283934A1/en not_active Abandoned
- 1998-03-18 WO PCT/SE1998/000490 patent/WO1998044000A1/en not_active Application Discontinuation
- 1998-03-18 NZ NZ337800A patent/NZ337800A/xx unknown
- 1998-03-18 JP JP54152998A patent/JP2002501373A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2002501373A (ja) | 2002-01-15 |
WO1998044000A1 (en) | 1998-10-08 |
AU741798B2 (en) | 2001-12-13 |
EP0996637A1 (en) | 2000-05-03 |
NZ337800A (en) | 2001-03-30 |
AU6934598A (en) | 1998-10-22 |
CA2283934A1 (en) | 1998-10-08 |
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