WO2004099408A8 - 新規蛋白質およびそれをコードするｄｎａ - Google Patents

新規蛋白質およびそれをコードするｄｎａ

Info

Publication number
WO2004099408A8
WO2004099408A8 PCT/JP2004/006515 JP2004006515W WO2004099408A8 WO 2004099408 A8 WO2004099408 A8 WO 2004099408A8 JP 2004006515 W JP2004006515 W JP 2004006515W WO 2004099408 A8 WO2004099408 A8 WO 2004099408A8
Authority
WO
WIPO (PCT)
Prior art keywords
protein
amino acid
acid sequence
activity
seq
Prior art date
Application number
PCT/JP2004/006515
Other languages
English (en)
French (fr)
Other versions
WO2004099408A1 (ja
Inventor
Takao Isogai
Tomoyasu Sugiyama
Tetsuji Otsuki
Ai Wakamatsu
Takahide Kaji
Toshimitsu Kishimoto
Wakako Watanabe
Hideo Kubodera
Original Assignee
Res Ass For Biotechnology
Takao Isogai
Tomoyasu Sugiyama
Tetsuji Otsuki
Ai Wakamatsu
Takahide Kaji
Toshimitsu Kishimoto
Wakako Watanabe
Hideo Kubodera
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Ass For Biotechnology, Takao Isogai, Tomoyasu Sugiyama, Tetsuji Otsuki, Ai Wakamatsu, Takahide Kaji, Toshimitsu Kishimoto, Wakako Watanabe, Hideo Kubodera filed Critical Res Ass For Biotechnology
Publication of WO2004099408A1 publication Critical patent/WO2004099408A1/ja
Publication of WO2004099408A8 publication Critical patent/WO2004099408A8/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

　本発明の目的は、完全長ｃＤＮＡライブラリーに含まれるｃＤＮＡクローンの塩基配列を解析し、このうちスプライシングバリアントを含む全長として配列が新規なｃＤＮＡについては、これがコードする蛋白質の生理活性を特定し、該生理活性に基づく蛋白質およびそれをコードするＤＮＡの利用方法を提案することである。本発明によれば、以下の（ａ）～（ｃ）のいずれかの蛋白質が提供される。（ａ）配列番号６または７に記載のアミノ酸配列からなる蛋白質、（ｂ）配列番号６または７に記載のアミノ酸配列において１もしくは数個のアミノ酸が欠失、置換および／または付加されたアミノ酸配列からなり、かつキナーゼ活性および／またはアポトーシス亢進活性を有する蛋白質。（ｃ）配列番号６または７に記載のアミノ酸配列における部分アミノ酸配列からなり、かつキナーゼ活性および／またはアポトーシス亢進活性を有する蛋白質。
PCT/JP2004/006515 2003-05-09 2004-05-07 新規蛋白質およびそれをコードするｄｎａ WO2004099408A1 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003-131392 2003-05-09
JP2003131392 2003-05-09

Publications (2)

Publication Number Publication Date
WO2004099408A1 WO2004099408A1 (ja) 2004-11-18
WO2004099408A8 true WO2004099408A8 (ja) 2005-02-03

Family

ID=33432131

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2004/006515 WO2004099408A1 (ja) 2003-05-09 2004-05-07 新規蛋白質およびそれをコードするｄｎａ

Country Status (1)

Country Link
WO (1) WO2004099408A1 (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2093298A3 (en) 2003-10-10 2009-09-23 Deutsches Krebsforschungszentrum Compositions for diagnosis and therapy of diseases associated with aberrant expression of Futrins (R-Spondins)
CA2664828A1 (en) 2006-10-20 2008-04-24 Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechts Rspondins as modulators of angiogenesis and vasculogenesis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1278859A2 (en) * 2000-04-10 2003-01-29 Sugen, Inc. Human protein kinases and protein kinase-like enzymes
JP2005512501A (ja) * 2000-12-06 2005-05-12 インサイト・ゲノミックス・インコーポレイテッド キナーゼおよびホスファターゼ
EP1485474A2 (en) * 2001-12-07 2004-12-15 Incyte Genomics, Inc. Kinases and phosphatases

Also Published As

Publication number Publication date
WO2004099408A1 (ja) 2004-11-18

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