WO2002040516A3 - DAS HELICOBACTER CYSTEIN RICH PROTEIN A (HcpA) UND SEINE ANWENDUNGEN - Google Patents

DAS HELICOBACTER CYSTEIN RICH PROTEIN A (HcpA) UND SEINE ANWENDUNGEN Download PDF

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Publication number
WO2002040516A3
WO2002040516A3 PCT/DE2001/004303 DE0104303W WO0240516A3 WO 2002040516 A3 WO2002040516 A3 WO 2002040516A3 DE 0104303 W DE0104303 W DE 0104303W WO 0240516 A3 WO0240516 A3 WO 0240516A3
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WO
WIPO (PCT)
Prior art keywords
hcpa
helicobacter
nucleic acid
rich protein
cysteine rich
Prior art date
Application number
PCT/DE2001/004303
Other languages
English (en)
French (fr)
Other versions
WO2002040516A2 (de
Inventor
Ludwig Deml
Wulf Schneider
Norbert Lehn
Original Assignee
Ludwig Deml
Wulf Schneider
Norbert Lehn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ludwig Deml, Wulf Schneider, Norbert Lehn filed Critical Ludwig Deml
Priority to EP01996552A priority Critical patent/EP1337647A2/de
Priority to DE10194938T priority patent/DE10194938D2/de
Priority to AU2002218985A priority patent/AU2002218985A1/en
Publication of WO2002040516A2 publication Critical patent/WO2002040516A2/de
Publication of WO2002040516A3 publication Critical patent/WO2002040516A3/de

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/205—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/86—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides, e.g. penicillinase (3.5.2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11—Medicinal preparations comprising living procariotic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Die vorliegende Erfindung betrifft Polynukleotide, umfassend eine Nukleinsäuresequenz gemäss SEQ ID NO: 1, 3, 5, 7 oder 9, oder dessen Fragment oder Derivat, oder ein Polynukleotid, das mit der Nukleinsäuresequenz gemäss SEQ ID NO: 1, 3, 5, 7, 9 oder 11 hybridisiert, kodierend das Helicobacter cystein rich Protein A (HcpA). Die vorliegende Erfindung betrifft ferner die Polypeptide, die von der Nukleinsäuresequenz oder Fragment oder Derivat der Nukleinsäuresequenz gemäss SEQ ID NO:1, 3, 5, 7, 9, oder 11 kodiert werden. Die vorliegende Erfindung betrifft ferner die Verwendung der Polynukleotide und Polypeptide.
PCT/DE2001/004303 2000-11-15 2001-11-15 DAS HELICOBACTER CYSTEIN RICH PROTEIN A (HcpA) UND SEINE ANWENDUNGEN WO2002040516A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP01996552A EP1337647A2 (de) 2000-11-15 2001-11-15 Das helicobacter cystein rich protein a (hcpa) und seine anwendungen
DE10194938T DE10194938D2 (de) 2000-11-15 2001-11-15 Das Helicobacter cystein rich Protein A(HcpA) und seine Anwendungen
AU2002218985A AU2002218985A1 (en) 2000-11-15 2001-11-15 Helicobacter cysteine rich protein a (hcpa) and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10056486 2000-11-15
DE10056486.0 2000-11-15

Publications (2)

Publication Number Publication Date
WO2002040516A2 WO2002040516A2 (de) 2002-05-23
WO2002040516A3 true WO2002040516A3 (de) 2002-08-08

Family

ID=7663317

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2001/004303 WO2002040516A2 (de) 2000-11-15 2001-11-15 DAS HELICOBACTER CYSTEIN RICH PROTEIN A (HcpA) UND SEINE ANWENDUNGEN

Country Status (4)

Country Link
EP (1) EP1337647A2 (de)
AU (1) AU2002218985A1 (de)
DE (1) DE10194938D2 (de)
WO (1) WO2002040516A2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006015445A1 (en) * 2004-08-13 2006-02-16 Marshall Barry J Bacterial delivery system
US8029777B2 (en) 2004-08-13 2011-10-04 Marshall Barry J Helicobacter system and uses thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997037044A1 (en) * 1996-03-29 1997-10-09 Astra Aktiebolag Nucleic acid and amino acid sequences relating to helicobacter pylori and vaccine compositions thereof
WO1998021225A1 (en) * 1996-11-14 1998-05-22 Merieux Oravax Helicobacter polypeptides and corresponding polynucleotide molecules
WO1998049314A2 (en) * 1997-04-25 1998-11-05 Genelabs Technologies, Inc. ANTIGENIC COMPOSITION AND METHOD OF DETECTION FOR $i(HELICOBACTER PYLORI)

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997037044A1 (en) * 1996-03-29 1997-10-09 Astra Aktiebolag Nucleic acid and amino acid sequences relating to helicobacter pylori and vaccine compositions thereof
WO1998021225A1 (en) * 1996-11-14 1998-05-22 Merieux Oravax Helicobacter polypeptides and corresponding polynucleotide molecules
WO1998049314A2 (en) * 1997-04-25 1998-11-05 Genelabs Technologies, Inc. ANTIGENIC COMPOSITION AND METHOD OF DETECTION FOR $i(HELICOBACTER PYLORI)

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CAO PING ET AL: "Extracellular release of antigenic proteins by Helicobacter pylori.", INFECTION AND IMMUNITY, vol. 66, no. 6, June 1998 (1998-06-01), pages 2984 - 2986, XP002198248, ISSN: 0019-9567 *
KARITA MIKIO ET AL: "Characterization of Helicobacter pylori dapE and construction of a conditionally lethal dapE mutant.", INFECTION AND IMMUNITY, vol. 65, no. 10, 1997, pages 4158 - 4164, XP002198249, ISSN: 0019-9567 *
MITTL PEER R E ET AL: "The cysteine-rich protein A from Helicobacter pylori is a beta-lactamase.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 275, no. 23, 9 June 2000 (2000-06-09), pages 17693 - 17699, XP002198247, ISSN: 0021-9258 *

Also Published As

Publication number Publication date
EP1337647A2 (de) 2003-08-27
AU2002218985A1 (en) 2002-05-27
DE10194938D2 (de) 2003-12-04
WO2002040516A2 (de) 2002-05-23

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