SE9202218D0 - Pharmacologically active alfa-(tertiary-aminomethyl)-benzenemethanol derivatives, pharmaceutical composition containing them, therapeutical use thereof and processes for their preparation - Google Patents

Pharmacologically active alfa-(tertiary-aminomethyl)-benzenemethanol derivatives, pharmaceutical composition containing them, therapeutical use thereof and processes for their preparation

Info

Publication number
SE9202218D0
SE9202218D0 SE9202218A SE9202218A SE9202218D0 SE 9202218 D0 SE9202218 D0 SE 9202218D0 SE 9202218 A SE9202218 A SE 9202218A SE 9202218 A SE9202218 A SE 9202218A SE 9202218 D0 SE9202218 D0 SE 9202218D0
Authority
SE
Sweden
Prior art keywords
processes
preparation
pharmaceutical composition
composition containing
pharmacologically active
Prior art date
Application number
SE9202218A
Other languages
English (en)
Swedish (sv)
Inventor
N-E Willman
Original Assignee
Kabi Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Pharmacia Ab filed Critical Kabi Pharmacia Ab
Priority to SE9202218A priority Critical patent/SE9202218D0/xx
Publication of SE9202218D0 publication Critical patent/SE9202218D0/xx
Priority to ZA935045A priority patent/ZA935045B/xx
Priority to TW082105750A priority patent/TW261605B/zh
Priority to SK76-95A priority patent/SK7695A3/sk
Priority to PCT/SE1993/000635 priority patent/WO1994002442A1/en
Priority to RU95104934A priority patent/RU2111205C1/ru
Priority to AU45950/93A priority patent/AU672989B2/en
Priority to DE69318715T priority patent/DE69318715D1/de
Priority to US08/374,611 priority patent/US5527821A/en
Priority to AT93916373T priority patent/ATE166339T1/de
Priority to CA002140781A priority patent/CA2140781C/en
Priority to EP93916373A priority patent/EP0651735B1/en
Priority to NZ254309A priority patent/NZ254309A/en
Priority to HU9500175A priority patent/HUT72632A/hu
Priority to BR9306870A priority patent/BR9306870A/pt
Priority to JP6504379A priority patent/JPH07509699A/ja
Priority to KR1019950700237A priority patent/KR950702522A/ko
Priority to CZ95133A priority patent/CZ13395A3/cs
Priority to MX9304403A priority patent/MX9304403A/es
Priority to CN93108986A priority patent/CN1085543A/zh
Priority to NO950177A priority patent/NO301760B1/no
Priority to FI950209A priority patent/FI950209A0/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/30Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/64Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
    • C07C217/66Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms with singly-bound oxygen atoms and six-membered aromatic rings bound to the same carbon atom of the carbon chain
    • C07C217/70Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms with singly-bound oxygen atoms and six-membered aromatic rings bound to the same carbon atom of the carbon chain linked by carbon chains having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SE9202218A 1992-07-22 1992-07-22 Pharmacologically active alfa-(tertiary-aminomethyl)-benzenemethanol derivatives, pharmaceutical composition containing them, therapeutical use thereof and processes for their preparation SE9202218D0 (sv)

Priority Applications (22)

Application Number Priority Date Filing Date Title
SE9202218A SE9202218D0 (sv) 1992-07-22 1992-07-22 Pharmacologically active alfa-(tertiary-aminomethyl)-benzenemethanol derivatives, pharmaceutical composition containing them, therapeutical use thereof and processes for their preparation
ZA935045A ZA935045B (en) 1992-07-22 1993-07-13 Pharmacologically active alfa-(tertiary-aminomethyl)-ben-zenemethanol derivatives
TW082105750A TW261605B (no) 1992-07-22 1993-07-17
CZ95133A CZ13395A3 (en) 1992-07-22 1993-07-20 Pharmacologically active alpha-(tert-aminomethyl(benzenemethanol derivatives
CA002140781A CA2140781C (en) 1992-07-22 1993-07-20 Pharmocologically active .alpha.-¬tertiary-aminomethyl|- benzenemethanol derivatives
NZ254309A NZ254309A (en) 1992-07-22 1993-07-20 Alpha-[tert.-aminomethyl)-benzenemethanol derivatives for treating urinary incontinence
RU95104934A RU2111205C1 (ru) 1992-07-22 1993-07-20 ПРОИЗВОДНЫЕ α -(ТРЕТИЧНОГО АМИНОМЕТИЛ)БЕНЗОЛМЕТАНОЛА И ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ИХ ОСНОВЕ
AU45950/93A AU672989B2 (en) 1992-07-22 1993-07-20 Pharmacologically active alpha-(tertiary-aminomethyl)-benzenemethanol derivatives
DE69318715T DE69318715D1 (de) 1992-07-22 1993-07-20 Pharmakologisch aktive alpha-(tertiär-aminoethyl)-phenylmethanol-derivate
US08/374,611 US5527821A (en) 1992-07-22 1993-07-20 Pharmacologically active alpha-[tertiary-aminomethyl]-benzenemethanol derivatives
AT93916373T ATE166339T1 (de) 1992-07-22 1993-07-20 Pharmakologisch aktive alpha-(tertiär-aminoethyl)-phenylmethanol-deriv te
SK76-95A SK7695A3 (en) 1992-07-22 1993-07-20 Pharmacologicaly active alpha-(tertiary-aminomethyl)-benzene methanol derivatives
EP93916373A EP0651735B1 (en) 1992-07-22 1993-07-20 Pharmacologically active alpha-(tertiary-aminomethyl)-phenylmethanol derivatives
PCT/SE1993/000635 WO1994002442A1 (en) 1992-07-22 1993-07-20 PHARMACOLOGICALLY ACTIVE α-[TERTIARY-AMINOMETHYL]-BENZENEMETHANOL DERIVATIVES
HU9500175A HUT72632A (en) 1992-07-22 1993-07-20 Pharmacologically active alpha-[tertiary-aminomethyl]-benzenemethanol derivatives, pharmaceutical compositions containing them and process for their preparation
BR9306870A BR9306870A (pt) 1992-07-22 1993-07-20 Derivados farmacologicamente ativos de (aminometila terciária) - benzenometanol
JP6504379A JPH07509699A (ja) 1992-07-22 1993-07-20 薬理学的に活性なα−〔第3−アミノメチル〕−ベンゼンメタノール誘導体
KR1019950700237A KR950702522A (ko) 1992-07-22 1993-07-20 약리학적으로 활성인 α-[t-아미노메틸]벤젠메탄올 유도체(PHARMACOLOGICALLY ACTIVE α-[TERTIARY-AMINOMETHYL]-BENENEMETHANOL DERIATIVES)
MX9304403A MX9304403A (es) 1992-07-22 1993-07-21 Derivados farmacologicamente activos de ó-(aminometilo terciario)-bencenmetanol
CN93108986A CN1085543A (zh) 1992-07-22 1993-07-22 有药理活性的α-[叔-氨基甲基]-苯甲醇衍生物
NO950177A NO301760B1 (no) 1992-07-22 1995-01-17 Farmakologisk aktive <alfa>-[tertiær-aminometyl]-benzenmetanolderivater, farmasöytiske preparater inneholdende disse samt anvendelse av forbindelsene for fremstilling av farmasöytiske preparater
FI950209A FI950209A0 (fi) 1992-07-22 1995-01-18 Farmakologisesti aktiiviset alfa-(tertiaarinen-amino-metyyli)-bentseenimetanolijohdannaiset

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9202218A SE9202218D0 (sv) 1992-07-22 1992-07-22 Pharmacologically active alfa-(tertiary-aminomethyl)-benzenemethanol derivatives, pharmaceutical composition containing them, therapeutical use thereof and processes for their preparation

Publications (1)

Publication Number Publication Date
SE9202218D0 true SE9202218D0 (sv) 1992-07-22

Family

ID=20386825

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9202218A SE9202218D0 (sv) 1992-07-22 1992-07-22 Pharmacologically active alfa-(tertiary-aminomethyl)-benzenemethanol derivatives, pharmaceutical composition containing them, therapeutical use thereof and processes for their preparation

Country Status (22)

Country Link
US (1) US5527821A (no)
EP (1) EP0651735B1 (no)
JP (1) JPH07509699A (no)
KR (1) KR950702522A (no)
CN (1) CN1085543A (no)
AT (1) ATE166339T1 (no)
AU (1) AU672989B2 (no)
BR (1) BR9306870A (no)
CA (1) CA2140781C (no)
CZ (1) CZ13395A3 (no)
DE (1) DE69318715D1 (no)
FI (1) FI950209A0 (no)
HU (1) HUT72632A (no)
MX (1) MX9304403A (no)
NO (1) NO301760B1 (no)
NZ (1) NZ254309A (no)
RU (1) RU2111205C1 (no)
SE (1) SE9202218D0 (no)
SK (1) SK7695A3 (no)
TW (1) TW261605B (no)
WO (1) WO1994002442A1 (no)
ZA (1) ZA935045B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19609847A1 (de) * 1996-03-13 1997-09-18 Gruenenthal Gmbh Dimethyl-(3-aryl-but-3-enyl)-aminverbindungen als pharmazeutische Wirkstoffe
EP1005861B1 (en) * 1997-04-11 2005-06-29 Nippon Shinyaku Co., Ltd. Remedies for frequent urination and urinary incontinence
US6008412A (en) * 1997-10-14 1999-12-28 Eli Lilly And Company Process to make chiral compounds
US6323231B1 (en) 2000-02-17 2001-11-27 Abbott Laboratories Use of α1A adrenoceptor agonists with α1B and α1D antagonism for the treatment of stress urinary incontinence
US6503190B1 (en) 2000-09-29 2003-01-07 Ethicon Endo-Surgery, Inc. Vaginal pessary
TW200510298A (en) * 2003-06-13 2005-03-16 Theravance Inc Substituted pyrrolidine and related compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE210031C (no) *
US4349549A (en) * 1981-05-18 1982-09-14 Syntex (U.S.A.) Inc. Anti-hypertensive 1-substituted spiro(piperidine-oxobenzoxazine)s
PL140232B1 (en) * 1982-07-05 1987-04-30 Warszawskie Zaklady Farma Method of obtaining derivatives of 1-aryl-2-aminoestanole
EP0103830A3 (de) * 1982-09-22 1985-07-31 Bayer Ag Wachstumsfördernde Phenylethylamin-Derivate
EP0213108A3 (de) * 1985-06-26 1987-07-15 Kurt Dr. Burghart Pharmazeutische Zubereitung mit einem Antihypotonikum als wirksames Mittel
AU642582B2 (en) * 1991-02-25 1993-10-21 Eli Lilly And Company Treatment of lower urinary tract disorders

Also Published As

Publication number Publication date
TW261605B (no) 1995-11-01
CA2140781A1 (en) 1994-02-03
EP0651735B1 (en) 1998-05-20
KR950702522A (ko) 1995-07-29
FI950209A (fi) 1995-01-18
FI950209A0 (fi) 1995-01-18
ZA935045B (en) 1994-02-07
AU672989B2 (en) 1996-10-24
SK7695A3 (en) 1995-07-11
WO1994002442A1 (en) 1994-02-03
AU4595093A (en) 1994-02-14
NO950177L (no) 1995-01-17
CA2140781C (en) 1998-09-29
CZ13395A3 (en) 1995-11-15
RU2111205C1 (ru) 1998-05-20
NZ254309A (en) 1996-08-27
DE69318715D1 (de) 1998-06-25
RU95104934A (ru) 1997-04-10
ATE166339T1 (de) 1998-06-15
NO301760B1 (no) 1997-12-08
BR9306870A (pt) 1998-12-08
EP0651735A1 (en) 1995-05-10
HUT72632A (en) 1996-05-28
NO950177D0 (no) 1995-01-17
JPH07509699A (ja) 1995-10-26
MX9304403A (es) 1994-04-29
HU9500175D0 (en) 1995-03-28
CN1085543A (zh) 1994-04-20
US5527821A (en) 1996-06-18

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