SE9000050L - LOW-DOSAGE COMPOSITION OF BENAZEPRIL / TIAZID DIETERIC - Google Patents

LOW-DOSAGE COMPOSITION OF BENAZEPRIL / TIAZID DIETERIC

Info

Publication number
SE9000050L
SE9000050L SE9000050A SE9000050A SE9000050L SE 9000050 L SE9000050 L SE 9000050L SE 9000050 A SE9000050 A SE 9000050A SE 9000050 A SE9000050 A SE 9000050A SE 9000050 L SE9000050 L SE 9000050L
Authority
SE
Sweden
Prior art keywords
bezenapril
diuretic agent
tiazid
dieteric
benazepril
Prior art date
Application number
SE9000050A
Other languages
Swedish (sv)
Other versions
SE506179C2 (en
Inventor
A Rosselet
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of SE9000050L publication Critical patent/SE9000050L/en
Publication of SE506179C2 publication Critical patent/SE506179C2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

PURPOSE: To prepare a composition, comprising bezenapril or its salt and a thiazide diuretic agent and capable of treating a lesser degree to a medium degree of hypertension in a lower dose than that when used alone. CONSTITUTION: This composition comprises bezenapril in about 4-6mg, preferably about 5mg dose at a time or its pharmaceutically permissible salt and a thiazide diuretic agent in an amount of 80-120%, preferably 100% based on 1/8 of the minimal antihyopertensive initial dose recommended when used alone. Bendroflumethiazide, Chlorthalidone, Chlorothiazide, hydrochlorothiazide, hydroflumethiazide, methylchlorothiazide, polythiazide, trichloromethiazide, benzthiazide and dichloroazide are cited as the thiazide diuretic agent. The most preferred composition comprises bezenapril hydrochloride and hydrochlorothiazide at about 0.8-1 weight ratio.
SE9000050A 1989-01-23 1990-01-08 Pharmaceutical low composition of benazepril and a thiazide diuretic SE506179C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30038389A 1989-01-23 1989-01-23

Publications (2)

Publication Number Publication Date
SE9000050L true SE9000050L (en) 1990-07-24
SE506179C2 SE506179C2 (en) 1997-11-17

Family

ID=23158879

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9000050A SE506179C2 (en) 1989-01-23 1990-01-08 Pharmaceutical low composition of benazepril and a thiazide diuretic

Country Status (24)

Country Link
JP (1) JP3009694B2 (en)
KR (1) KR0141479B1 (en)
AT (1) AT401728B (en)
AU (1) AU629288B2 (en)
BE (1) BE1002736A4 (en)
CA (1) CA2008126C (en)
CH (1) CH680568A5 (en)
CY (1) CY1835A (en)
DE (2) DE4001496C2 (en)
DK (1) DK175204B1 (en)
FR (1) FR2641971B1 (en)
GB (1) GB2227172B (en)
HK (1) HK98995A (en)
IE (1) IE61784B1 (en)
IL (1) IL93117A0 (en)
IT (1) IT1239744B (en)
LU (1) LU87660A1 (en)
MX (1) MX9203362A (en)
NL (1) NL194958C (en)
NZ (1) NZ232182A (en)
SA (1) SA90100151B1 (en)
SE (1) SE506179C2 (en)
SG (1) SG176194G (en)
ZA (1) ZA90429B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100221695B1 (en) * 1991-08-12 1999-09-15 그린 마틴, 브라이언 쥐 테슬리 Pharmaceutical spheroid formulation
DK9200258U4 (en) * 1992-03-11 1993-07-23 Merck & Co Inc Pharmaceutical preparation containing enalapril for use in hypertension
GB9613470D0 (en) * 1996-06-27 1996-08-28 Ciba Geigy Ag Small solid oral dosage form
CN102579346B (en) * 2012-03-02 2013-09-25 海南美兰史克制药有限公司 Liposome solid preparation of benazepril/hydrochlorothiazide medicine combination

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4217347A (en) * 1977-12-27 1980-08-12 E. R. Squibb & Sons, Inc. Method of treating hypertension and medicaments therefor
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
US4410520A (en) * 1981-11-09 1983-10-18 Ciba-Geigy Corporation 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids
ZA833903B (en) * 1982-06-01 1984-11-28 Merck & Co Inc Benzofused lactams as antihypertensives
US4520021A (en) * 1982-07-02 1985-05-28 Merck & Co., Inc. Substituted caprolactam derivatives as antihypertensives

Also Published As

Publication number Publication date
JP3009694B2 (en) 2000-02-14
ZA90429B (en) 1990-09-26
LU87660A1 (en) 1991-02-18
KR0141479B1 (en) 1998-06-01
CH680568A5 (en) 1992-09-30
AU629288B2 (en) 1992-10-01
IE900233L (en) 1990-07-23
GB2227172B (en) 1992-06-10
IT1239744B (en) 1993-11-15
DE10199041I1 (en) 2002-01-10
IE61784B1 (en) 1994-11-30
FR2641971A1 (en) 1990-07-27
NL9000158A (en) 1990-08-16
DK175204B1 (en) 2004-07-12
BE1002736A4 (en) 1991-05-21
HK98995A (en) 1995-06-30
DK17490A (en) 1990-07-24
AT401728B (en) 1996-11-25
DE4001496C2 (en) 2001-05-10
KR900011465A (en) 1990-08-01
IT9047548A1 (en) 1991-07-19
GB2227172A (en) 1990-07-25
NL194958C (en) 2003-09-02
MX9203362A (en) 1992-07-01
AU4870390A (en) 1990-07-26
CA2008126A1 (en) 1990-07-23
DE4001496A1 (en) 1990-07-26
FR2641971B1 (en) 1991-11-22
SE506179C2 (en) 1997-11-17
SG176194G (en) 1995-05-12
IL93117A0 (en) 1990-11-05
DK17490D0 (en) 1990-01-22
NL194958B (en) 2003-05-01
IT9047548A0 (en) 1990-01-19
CA2008126C (en) 1999-11-09
GB9001054D0 (en) 1990-03-14
ATA13590A (en) 1996-04-15
CY1835A (en) 1995-12-01
NZ232182A (en) 1991-06-25
JPH02233616A (en) 1990-09-17
SA90100151B1 (en) 2006-10-02

Similar Documents

Publication Publication Date Title
ES2184800T3 (en) USE OF ANTI-VEGF AGENTS IN THE TREATMENT OF ENDOMETRIOSIS.
TR199801179T2 (en) New taxoids, their preparations and drug compositions.
ID28003A (en) ADAMANTANA'S DEMONS
NO931635D0 (en) PROCEDURE FOR THE PREPARATION OF CHINAZOLINE DERIVATIVES
KR960013371A (en) Pharmaceutical mixture
TR199901172T2 (en) Newly substituted pyrazole derivatives.
PL323490A1 (en) Tetralinic compounds exibiting acitity against multgiple-drug refractoriness
CA2195425A1 (en) Use of a progesterone antagonist and of a gestagen for the treatment of endometriosis or leiomyomata uteri
TR200200795T2 (en) Piperazine derivatives as 5-HT1B antagonists
ES2074769T3 (en) PROCEDURE FOR THE PREPARATION OF A PHARMACEUTICAL PREPARATION WITH AT LEAST TWO DIFFERENT ACTIVE PRINCIPLES AND USE OF A PREPARATION OF THIS TYPE.
HU9602668D0 (en) Progesterone antagonists useful preparing medicaments for treating dysfunctional uterine bleeding
Kumar et al. Priapism as a rare presentation of chronic myeloid leukemia
SE9000050L (en) LOW-DOSAGE COMPOSITION OF BENAZEPRIL / TIAZID DIETERIC
NZ240481A (en) Aminosulphonyl urea derivatives and pharmaceutical compositions
ES2056978T3 (en) PROSTHETIC ARTICLE.
BR0207066A (en) 2h-1-benzopyran derivatives - processes for their preparation and pharmaceutical compositions from them
IT1255076B (en) BIODEGRADABLE MICROSPHERES FOR PHARMACEUTICAL AND COSMETIC USE
AU3777197A (en) Cyclosporin formulation
TR199801126T2 (en) Quick-release tablet containing tolfenamic acid or a pharmaceutically acceptable salt thereof.
ATE181324T1 (en) SECO-D STEROIDS ACTIVE IN THE CARDIOVASCULAR SYSTEM AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME
IE831030L (en) Benzopyrans and benzothiopyrans
GEP20032975B (en) Echinocandin Derivatives, Preparation Method and Pharmaceutical Composition
IE840977L (en) Pharmaceutical preparations
EP0145361A3 (en) Acetylene derivatives for the treatment of hypertension and angina
DE59903977D1 (en) IMIDAZOTRIAZOLOPYRIMIDINE AS A MEDICINAL PRODUCT WITH ADENOSIN ANTAGONISTIC EFFECT

Legal Events

Date Code Title Description
NUG Patent has lapsed