BE1002736A4 - ANTIHYPERTENSIVE PHARMACEUTICAL COMPOSITION COMBINING BENAZEPRIL AND A THIAZIDE DIURETIC. - Google Patents

ANTIHYPERTENSIVE PHARMACEUTICAL COMPOSITION COMBINING BENAZEPRIL AND A THIAZIDE DIURETIC. Download PDF

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Publication number
BE1002736A4
BE1002736A4 BE9000074A BE9000074A BE1002736A4 BE 1002736 A4 BE1002736 A4 BE 1002736A4 BE 9000074 A BE9000074 A BE 9000074A BE 9000074 A BE9000074 A BE 9000074A BE 1002736 A4 BE1002736 A4 BE 1002736A4
Authority
BE
Belgium
Prior art keywords
pharmaceutical composition
thiazide diuretic
benazepril
composition combining
antihypertensive pharmaceutical
Prior art date
Application number
BE9000074A
Other languages
French (fr)
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Application granted granted Critical
Publication of BE1002736A4 publication Critical patent/BE1002736A4/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

L'invention concerne une composition pharmaceutique antihypertensive associant le bénazépril ou un sel pharmaceutiquement acceptable de celui-ci et un diurétique thiazidique. Une composition particulièrement préférée contient environ 4 à 6 mg de chlorhydrate de bénazépril et environ 5 à 7,5 mg d'hydrochlorothiazide par forme unitaire d'administration.The invention relates to an antihypertensive pharmaceutical composition combining benazepril or a pharmaceutically acceptable salt thereof and a thiazide diuretic. A particularly preferred composition contains about 4 to 6 mg of benazepril hydrochloride and about 5 to 7.5 mg of hydrochlorothiazide per unit administration form.

BE9000074A 1989-01-23 1990-01-22 ANTIHYPERTENSIVE PHARMACEUTICAL COMPOSITION COMBINING BENAZEPRIL AND A THIAZIDE DIURETIC. BE1002736A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30038389A 1989-01-23 1989-01-23

Publications (1)

Publication Number Publication Date
BE1002736A4 true BE1002736A4 (en) 1991-05-21

Family

ID=23158879

Family Applications (1)

Application Number Title Priority Date Filing Date
BE9000074A BE1002736A4 (en) 1989-01-23 1990-01-22 ANTIHYPERTENSIVE PHARMACEUTICAL COMPOSITION COMBINING BENAZEPRIL AND A THIAZIDE DIURETIC.

Country Status (24)

Country Link
JP (1) JP3009694B2 (en)
KR (1) KR0141479B1 (en)
AT (1) AT401728B (en)
AU (1) AU629288B2 (en)
BE (1) BE1002736A4 (en)
CA (1) CA2008126C (en)
CH (1) CH680568A5 (en)
CY (1) CY1835A (en)
DE (2) DE4001496C2 (en)
DK (1) DK175204B1 (en)
FR (1) FR2641971B1 (en)
GB (1) GB2227172B (en)
HK (1) HK98995A (en)
IE (1) IE61784B1 (en)
IL (1) IL93117A0 (en)
IT (1) IT1239744B (en)
LU (1) LU87660A1 (en)
MX (1) MX9203362A (en)
NL (1) NL194958C (en)
NZ (1) NZ232182A (en)
SA (1) SA90100151B1 (en)
SE (1) SE506179C2 (en)
SG (1) SG176194G (en)
ZA (1) ZA90429B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100221695B1 (en) * 1991-08-12 1999-09-15 그린 마틴, 브라이언 쥐 테슬리 Pharmaceutical spheroid formulation
DK9200258U4 (en) * 1992-03-11 1993-07-23 Merck & Co Inc Pharmaceutical preparation containing enalapril for use in hypertension
GB9613470D0 (en) * 1996-06-27 1996-08-28 Ciba Geigy Ag Small solid oral dosage form
CN102579346B (en) * 2012-03-02 2013-09-25 海南美兰史克制药有限公司 Liposome solid preparation of benazepril/hydrochlorothiazide medicine combination

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4217347A (en) * 1977-12-27 1980-08-12 E. R. Squibb & Sons, Inc. Method of treating hypertension and medicaments therefor
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
US4410520A (en) * 1981-11-09 1983-10-18 Ciba-Geigy Corporation 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids
ZA833903B (en) * 1982-06-01 1984-11-28 Merck & Co Inc Benzofused lactams as antihypertensives
US4520021A (en) * 1982-07-02 1985-05-28 Merck & Co., Inc. Substituted caprolactam derivatives as antihypertensives

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 109, no. 11, 12 septembre 1988, page 20, abrégé no. 85755s, Columbus, Ohio, US; I. DE LEPELEIRE et al.: "Interaction between furosemide and the converting enzyme inhibitor benazepril in healthy volunteers", & EUR. J. CLIN. PHARMACOL. 1988, 34(5), 465-8 *
CHEMICAL ABSTRACTS, vol. 110, no. 23, 5 juin 1989, page 39, abrégé no. 205308t, Columbus, Ohio, US; J.J. WHALEN et al.: "Definition of the effective dose of the converting-enzyme inhibitor benazepril", & AM. HEART J. 1989, 117(3), 728-34 *

Also Published As

Publication number Publication date
JP3009694B2 (en) 2000-02-14
ZA90429B (en) 1990-09-26
LU87660A1 (en) 1991-02-18
KR0141479B1 (en) 1998-06-01
CH680568A5 (en) 1992-09-30
AU629288B2 (en) 1992-10-01
IE900233L (en) 1990-07-23
GB2227172B (en) 1992-06-10
IT1239744B (en) 1993-11-15
DE10199041I1 (en) 2002-01-10
IE61784B1 (en) 1994-11-30
FR2641971A1 (en) 1990-07-27
NL9000158A (en) 1990-08-16
DK175204B1 (en) 2004-07-12
SE9000050L (en) 1990-07-24
HK98995A (en) 1995-06-30
DK17490A (en) 1990-07-24
AT401728B (en) 1996-11-25
DE4001496C2 (en) 2001-05-10
KR900011465A (en) 1990-08-01
IT9047548A1 (en) 1991-07-19
GB2227172A (en) 1990-07-25
NL194958C (en) 2003-09-02
MX9203362A (en) 1992-07-01
AU4870390A (en) 1990-07-26
CA2008126A1 (en) 1990-07-23
DE4001496A1 (en) 1990-07-26
FR2641971B1 (en) 1991-11-22
SE506179C2 (en) 1997-11-17
SG176194G (en) 1995-05-12
IL93117A0 (en) 1990-11-05
DK17490D0 (en) 1990-01-22
NL194958B (en) 2003-05-01
IT9047548A0 (en) 1990-01-19
CA2008126C (en) 1999-11-09
GB9001054D0 (en) 1990-03-14
ATA13590A (en) 1996-04-15
CY1835A (en) 1995-12-01
NZ232182A (en) 1991-06-25
JPH02233616A (en) 1990-09-17
SA90100151B1 (en) 2006-10-02

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Legal Events

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CA Change of address of the owner of the patent
CH Change of patent owner
RE20 Patent expired

Owner name: *NOVARTIS A.G.

Effective date: 20100122