SE8901660D0 - APPLICATION OF GONADOLIBERIN DERIVATIVES FOR THE PREPARATION OF TUMOR INHIBITORING PHARMACEUTICAL COMPOSITIONS - Google Patents

APPLICATION OF GONADOLIBERIN DERIVATIVES FOR THE PREPARATION OF TUMOR INHIBITORING PHARMACEUTICAL COMPOSITIONS

Info

Publication number
SE8901660D0
SE8901660D0 SE8901660A SE8901660A SE8901660D0 SE 8901660 D0 SE8901660 D0 SE 8901660D0 SE 8901660 A SE8901660 A SE 8901660A SE 8901660 A SE8901660 A SE 8901660A SE 8901660 D0 SE8901660 D0 SE 8901660D0
Authority
SE
Sweden
Prior art keywords
group
stands
4alkyl
glycyl
pharmaceutical compositions
Prior art date
Application number
SE8901660A
Other languages
Swedish (sv)
Other versions
SE8901660L (en
Inventor
Ri G K
Original Assignee
Innofinance Altalanos Innovaci
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innofinance Altalanos Innovaci filed Critical Innofinance Altalanos Innovaci
Publication of SE8901660D0 publication Critical patent/SE8901660D0/en
Publication of SE8901660L publication Critical patent/SE8901660L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)

Abstract

Pharmaceutical compositions for treating hormone-dependent tumours without inducing hormonal castration contain a gonadoliberin derivative of general formula (I), Gip-His-Trp-Ser-Tyr-X1-X2-X3-Pro-X4 (I) wherein X1 stands for a glycyl group or a D-isomer of any native or synthetic aromatic D-amino acid group; X2 stands for an L-amino acid group bearing a C1-4alkyl or L-phenylalanyl or L-tryptophyl group; X3 stands for an L-amino-acid residue bearing a C1-4alkyl or C2-4alkanoyl amide side chain; and X4 means a glycyl amide or C1-4alkyl amide group, with the proviso that X3 means a group different from leucyl when X2 stands for a tryptophyl group and X1 is other than glycyl group, its addition salts formed with pharmaceutically acceptable acids or metal complexes.
SE8901660A 1988-05-10 1989-05-10 APPLICATION OF GONADOLIBERIN DERIVATIVES FOR THE PREPARATION OF TUMOR INHIBITORING PHARMACEUTICAL COMPOSITIONS SE8901660L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU882347A HU199694B (en) 1988-05-10 1988-05-10 Process for producing citostatic pharmaceutical compositions containing gonadoliberin derivatives

Publications (2)

Publication Number Publication Date
SE8901660D0 true SE8901660D0 (en) 1989-05-10
SE8901660L SE8901660L (en) 1989-11-11

Family

ID=10958948

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8901660A SE8901660L (en) 1988-05-10 1989-05-10 APPLICATION OF GONADOLIBERIN DERIVATIVES FOR THE PREPARATION OF TUMOR INHIBITORING PHARMACEUTICAL COMPOSITIONS

Country Status (16)

Country Link
JP (1) JPH0215097A (en)
KR (1) KR900017610A (en)
BE (1) BE1004932A3 (en)
CH (1) CH678013A5 (en)
DE (1) DE3915317A1 (en)
DK (1) DK228289A (en)
FI (1) FI892275A (en)
FR (1) FR2631237A1 (en)
GB (1) GB2218335B (en)
GR (1) GR890100315A (en)
HU (1) HU199694B (en)
IL (1) IL89998A0 (en)
IT (1) IT1229251B (en)
LU (1) LU87516A1 (en)
NL (1) NL8901159A (en)
SE (1) SE8901660L (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5760000A (en) * 1994-05-13 1998-06-02 University Technologies International,Inc. Inhibition of liver cancer by the use of GnRH and GnRH analogs
US6054432A (en) * 1996-09-12 2000-04-25 Asta Medica Aktiengesellschaft Means for treating prostate hypertrophy and prostate cancer

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4410514A (en) * 1982-12-06 1983-10-18 The Salk Institute For Biological Studies GnRH Agonists
HU189394B (en) * 1983-12-23 1986-06-30 Koezponti Valto- Es Hitelbank Rt Innovacios Alap,Hu Method for producing spermatozoa suitable for fertilization from mature fishes
IT1178775B (en) * 1983-12-23 1987-09-16 Konzponti Valto Es Hitelbank R GONADOLIBERINE DERIVATIVES AND PROCEDURE FOR THEIR PREPARATION
US4760053A (en) * 1984-08-02 1988-07-26 Fernand Labrie Combination therapy for selected sex steroid dependent cancers
ATE75947T1 (en) * 1984-08-02 1992-05-15 Labrie Fernand PHARMACEUTICAL COMPOSITION FOR COMBINATION THERAPY OF HORMONAL DEPENDENT CANCER.
HU193607B (en) * 1985-07-18 1987-11-30 Innofinance Altalanos Innovaci Process for production of sexual products applyable for natural or artificial insemination for mammates
US4721775A (en) * 1985-08-26 1988-01-26 Board Of Regents, The University Of Texas System Effective peptides related to the luteinizing hormone releasing hormone from L-amino acids
HU194913B (en) * 1986-01-03 1988-03-28 Innofinance Altalanos Innovaci Process for producing novel gonadoliberin derivatives containing in the sixth position aromatic amino carboxylic acid and medical preparations containing these compounds

Also Published As

Publication number Publication date
FR2631237A1 (en) 1989-11-17
CH678013A5 (en) 1991-07-31
GR890100315A (en) 1990-03-12
IT8920435A0 (en) 1989-05-11
HUT49813A (en) 1989-11-28
NL8901159A (en) 1989-12-01
LU87516A1 (en) 1990-12-11
GB8910724D0 (en) 1989-06-28
DK228289A (en) 1989-11-11
DK228289D0 (en) 1989-05-10
HU199694B (en) 1990-03-28
IT1229251B (en) 1991-07-26
JPH0215097A (en) 1990-01-18
KR900017610A (en) 1990-12-19
DE3915317A1 (en) 1989-11-23
GB2218335B (en) 1991-09-25
SE8901660L (en) 1989-11-11
FI892275A0 (en) 1989-05-10
BE1004932A3 (en) 1993-03-02
GB2218335A (en) 1989-11-15
FI892275A (en) 1989-11-11
IL89998A0 (en) 1989-12-15

Similar Documents

Publication Publication Date Title
BG103335A (en) Application of fumaric acid derivatives
CA2134348A1 (en) Polysaccharide derivatives and drug carriers
FI945912A0 (en) Proteinoid carriers and methods for their preparation and their use
MD1233B1 (en) Erythromycin derivatives, process for their preparation and pharmaceutical composition on base thereof
KR900002801A (en) Pharmaceutical preparations for treating diabetes
ES2178000T3 (en) COMPOSITIONS AND METHODS TO TREAT INFECTIONS USING INDOLICIDINE ANALOGS.
BR9815159A (en) Preparation of site-specific polyethylene glycol-grf conjugates
ES2032382T3 (en) METHOD FOR PREPARING A MEDICATION FOR THE PREVENTION OR TREATMENT OF ENDOMETRIOSIS.
ATE513847T1 (en) BIOACTIVE PEPTIDES
CY1109107T1 (en) Peptides and / or Proteins both and their use for the preparation of a therapeutic and / or prophylactic drug
ES2107470T3 (en) PRODUCT THAT CONTAINS GROWTH FACTOR AND GLUTAMINE AND USE OF GROWTH FACTOR FOR THE TREATMENT OF INTESTINAL MUCOSA.
BR0009472A (en) Lhrh antagonists with improved solubility properties
AU7683296A (en) Peptide conjugates derived from thymic hormones, their use as medicament and compositions containing them
AU7683196A (en) Peptide conjugates, use thereof as a drug, and compositions containing same
BR9809103A (en) Stable pharmaceutical form of administration for peptides, proteins and nucleic acids
SE8901660L (en) APPLICATION OF GONADOLIBERIN DERIVATIVES FOR THE PREPARATION OF TUMOR INHIBITORING PHARMACEUTICAL COMPOSITIONS
SE8700016L (en) GONADOLIBER INGREDIENTS CONTAINING AN AROMATIC AMINOCARBOXYLIC ACID, 6 PHARMACEUTICAL AND VETERINARY MEDICINAL COMPOSITIONS CONTAINING THEM AND PROCEDURE FOR THE PREPARATION OF THE SAME
EP0272684A3 (en) Derivatives of n-(methylsulphonylphenylethyl)-2-propenamides and their use as antibiotics
DK628388D0 (en) VINCRIST CONTAINING PRODUCT
ES2184121T3 (en) FORMULATION FOR THE TREATMENT AND / OR PROFILAXIS OF DEMENTIA.
DE3882233T2 (en) VESSEL-ACTIVE PEPTIDES.
CY1106169T1 (en) COMPOSITION OF PROPIONYL L-CARNITINE AND GLYCINE FOR THE PREVENTION AND/OR TREATMENT OF CYTOTOXIC EFFECTS INDUCED BY THE USE OF IMMUNOSUPPRESSANT AGENTS
IT1241459B (en) Pharmaceutical compositions for the rectal administration of calcitonin.
IT1254688B (en) Targeted release pharmaceutical compositions for oral administration containing ursodeoxycholic acid and chenodeoxycholic acid
SE9003040D0 (en) ANALOGUES OF CYCLOLINOPEPTIDE AND THE USE THEREOF

Legal Events

Date Code Title Description
NAV Patent application has lapsed

Ref document number: 8901660-4

Effective date: 19940527